01-674-163
AIF Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-163-Each-of-1 | In Stock | ₹ 45,004.56 |
01-674-163 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,004.56
GST (18%): ₹ 8,100.821
Total Price: ₹ 53,105.381
Antigen
AIF
Classification
Polyclonal
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O95831
Gene Symbols
AIFM1
Immunogen
Synthetic peptide corresponding to residues 109-122 of human AIF.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
AIFM1
Gene Alias
Apoptosis-inducing factor 1 mitochondrial, Apoptosis-inducing factor 1, PDCD8
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
9131
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- A suggested positive control for this product is K562 cell lysate
- Apoptosis Inducing Factor (AIF) causes chromatin condensation and DNA fragmentation
- AIF was recently identified, and cloned
- Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation
- These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins
- Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria
- AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9
- AIF induces chromatin condensation and large scale DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection and apoptosis stimuli
- AIF is highly conserved between human and mouse and widely expressed
- Mutations in the AIF gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy
- Alternative splicing results in multiple transcript variants of AIF and a related pseudogene has been identified on chromosome 10.
Compare Similar Items
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Antigen: AIF
Classification: Polyclonal
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O95831
Gene Symbols: AIFM1
Immunogen: Synthetic peptide corresponding to residues 109-122 of human AIF.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: AIFM1
Gene Alias: Apoptosis-inducing factor 1 mitochondrial, Apoptosis-inducing factor 1, PDCD8
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9131
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
AIF
Classification:
Polyclonal
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O95831
Gene Symbols:
AIFM1
Immunogen:
Synthetic peptide corresponding to residues 109-122 of human AIF.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
AIFM1
Gene Alias:
Apoptosis-inducing factor 1 mitochondrial, Apoptosis-inducing factor 1, PDCD8
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9131
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: DNase II
Classification: Polyclonal
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O00115
Gene Symbols: DNASE2
Immunogen: Synthetic peptide corresponding to residues 347-360 of human DNase II precursor.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: DNASE2
Gene Alias: DNASE2A, DNL, DNL2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1777
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
DNase II
Classification:
Polyclonal
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O00115
Gene Symbols:
DNASE2
Immunogen:
Synthetic peptide corresponding to residues 347-360 of human DNase II precursor.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
DNASE2
Gene Alias:
DNASE2A, DNL, DNL2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1777
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Caspase 9
Classification: Polyclonal
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P55211
Gene Symbols: CASP9
Immunogen: Synthetic peptide corresponding to residues 299-318 of human caspase-9.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: CASP9
Gene Alias: RP11-265F14.3, APAF-3, APAF3, CASPASE-9c, ICE-LAP6, MCH6, cas9
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 842
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Caspase 9
Classification:
Polyclonal
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P55211
Gene Symbols:
CASP9
Immunogen:
Synthetic peptide corresponding to residues 299-318 of human caspase-9.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
CASP9
Gene Alias:
RP11-265F14.3, APAF-3, APAF3, CASPASE-9c, ICE-LAP6, MCH6, cas9
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
842
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Caspase 10
Classification: Polyclonal
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q92851
Gene Symbols: CASP10
Immunogen: Synthetic peptide corresponding to residues 505-521 of human FLICE2.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: CASP10
Gene Alias: ALPS2, FLICE2, MCH4
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 843
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Caspase 10
Classification:
Polyclonal
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q92851
Gene Symbols:
CASP10
Immunogen:
Synthetic peptide corresponding to residues 505-521 of human FLICE2.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
CASP10
Gene Alias:
ALPS2, FLICE2, MCH4
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
843
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid