01-674-166
Caspase 9 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-166-Each-of-1 | In Stock | ₹ 47,571.36 |
01-674-166 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,571.36
GST (18%): ₹ 8,562.845
Total Price: ₹ 56,134.205
Antigen
Caspase 9
Classification
Polyclonal
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P55211
Gene Symbols
CASP9
Immunogen
Synthetic peptide corresponding to residues 299-318 of human caspase-9.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
CASP9
Gene Alias
RP11-265F14.3, APAF-3, APAF3, CASPASE-9c, ICE-LAP6, MCH6, cas9
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
842
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- A suggested positive control for this product is HeLa whole cell lysate
- Caspase 9 (ICE-like apoptotic protease 6, ICE LAP6, apoptotic protease Mch6, apoptotic protease activating factor 3, Apaf3) is a member of the peptidase family C14 that contains a CARD domain
- Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates
- Caspase 9 is active as a heterotetramer, is present in the cytosol and, upon activation, translocates to the mitochondria
- Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6
- Further, Caspase 9 is involved in the activation cascade of caspases responsible for apoptosis execution
- Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3
- Caspase 9 promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner, and proteolytically cleaves poly(ADP- ribose) polymerase (PARP)
- Caspase 9 is expressed in variety of human tissues
- An isoform of rat Caspase-9 has been identified in which the C terminus of full-length Caspase-9 is replaced with an alternative peptide sequence
- Mutations in Caspase 9 affect brain development
- In mice, insufficient Caspase 9 have resulted in abnormal cerebrum development and neuron development
- In humans, dysfunctional Caspase 9 expression vary from tissue to tissue
- Low levels of Caspase 9 may play a role in cancer development and neurodegenerative diseases such as Alzheimer’s Disease (AD).
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Antigen: Caspase 9
Classification: Polyclonal
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P55211
Gene Symbols: CASP9
Immunogen: Synthetic peptide corresponding to residues 299-318 of human caspase-9.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: CASP9
Gene Alias: RP11-265F14.3, APAF-3, APAF3, CASPASE-9c, ICE-LAP6, MCH6, cas9
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 842
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Caspase 9
Classification:
Polyclonal
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P55211
Gene Symbols:
CASP9
Immunogen:
Synthetic peptide corresponding to residues 299-318 of human caspase-9.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
CASP9
Gene Alias:
RP11-265F14.3, APAF-3, APAF3, CASPASE-9c, ICE-LAP6, MCH6, cas9
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
842
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Caspase 10
Classification: Polyclonal
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q92851
Gene Symbols: CASP10
Immunogen: Synthetic peptide corresponding to residues 505-521 of human FLICE2.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: CASP10
Gene Alias: ALPS2, FLICE2, MCH4
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 843
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Caspase 10
Classification:
Polyclonal
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q92851
Gene Symbols:
CASP10
Immunogen:
Synthetic peptide corresponding to residues 505-521 of human FLICE2.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
CASP10
Gene Alias:
ALPS2, FLICE2, MCH4
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
843
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Caspase 12
Classification: Polyclonal
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q6UXS9, O08736, Q920D5
Gene Symbols: CASP12
Immunogen: Synthetic peptide corresponding to residues 100-116 of the murine caspase-12.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: CASP12
Gene Alias: __
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100506742, 12364, 156117
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Caspase 12
Classification:
Polyclonal
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q6UXS9, O08736, Q920D5
Gene Symbols:
CASP12
Immunogen:
Synthetic peptide corresponding to residues 100-116 of the murine caspase-12.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
CASP12
Gene Alias:
__
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100506742, 12364, 156117
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Amyloid Precursor Protein
Classification: Polyclonal
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P05067, P12023, P08592
Gene Symbols: APP
Immunogen: Synthetic peptide corresponding to residues 653-662 of human amyloid A4 protein precursor.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: APP
Gene Alias: Amyloid beta A4 protein, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP; Protease nexin-II, PN-II, APPI, PreA4, A4,
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11820, 351, 54226
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Amyloid Precursor Protein
Classification:
Polyclonal
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P05067, P12023, P08592
Gene Symbols:
APP
Immunogen:
Synthetic peptide corresponding to residues 653-662 of human amyloid A4 protein precursor.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
APP
Gene Alias:
Amyloid beta A4 protein, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP; Protease nexin-II, PN-II, APPI, PreA4, A4,
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11820, 351, 54226
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid