01-674-583
TMP21 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-583-Each-of-1 | In Stock | ₹ 44,705.10 |
01-674-583 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
TMP21
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TMED10
Gene Alias
1110014C03Rik; 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein; hypothetical protein; integral membrane protein p23; integral membrane protein Tmp21-I (p23); p23; p24 family protein delta-1; P24(DELTA); p24d1; p24delta; p24delta1; S31I125; S31III125; testicular tissue protein Li 206; tmed10; tmed10.L; TMP21; Tmp-21-I; transmembrane emp24 domain-containing protein 10; transmembrane emp24-like trafficking protein 10; transmembrane emp24-like trafficking protein 10 (yeast); transmembrane p24 trafficking protein 10; transmembrane p24 trafficking protein 10 L homeolog; transmembrane protein; transmembrane protein tmp21; transmembrane trafficking protein; transmembrane trafficking protein 21; XELAEV_18000191mg; Xp24d2; Xp24delta2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100009296, 10972, 379442, 529761, 68581, 84599
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.95 mg/mL
Formulation
PBS with 30% glycerol and 0.1% sodium azide
Gene Accession No.
P49755, Q28735, Q5E971, Q63584, Q9D1D4
Gene Symbols
TMED10, tmed10.L
Immunogen
Synthetic internal peptide corresponding to residues 50-150 of the human TMP21 protein.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bovine, Human, Mouse, Non-human Primate, Rabbit, Rat, X. laevis
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Suggested positive control: human liver protein
- TMP21 is a ubiquitously expressed protein that is involved in vesicular targeting and protein transport
- More recent experiments have shown that it is also a component in the presenilin complex and modulates the -gamma-secretase but not the epsilon-secretase cleavage activity of the amyloid precursor protein
- The presenilin complex is composed of the proteins APH1, nicastrin, and PEN2 in addition to presenilin-1
- Together, these proteins cleave the amyloid precursor protein at what is known as the -gamma- and epsilon-sites and can lead to the accumulation of the Abeta cleavage product that is associated with Alzheimer's disease
- Co-immunoprecipitation experiments using antibodies against these proteins also yielded TMP21 indicating that TMP21 may play a role in the regulation of this complex
- Suppression of TMP21 expression by siRNA in transfected cells caused increased -gamma-secretase activity but not epsilon-secretase activity, and increased Abeta production, demonstrating that TMP21 can modulate -gamma-secretase activity.
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Antigen: TMP21
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TMED10
Gene Alias: 1110014C03Rik; 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein; hypothetical protein; integral membrane protein p23; integral membrane protein Tmp21-I (p23); p23; p24 family protein delta-1; P24(DELTA); p24d1; p24delta; p24delta1; S31I125; S31III125; testicular tissue protein Li 206; tmed10; tmed10.L; TMP21; Tmp-21-I; transmembrane emp24 domain-containing protein 10; transmembrane emp24-like trafficking protein 10; transmembrane emp24-like trafficking protein 10 (yeast); transmembrane p24 trafficking protein 10; transmembrane p24 trafficking protein 10 L homeolog; transmembrane protein; transmembrane protein tmp21; transmembrane trafficking protein; transmembrane trafficking protein 21; XELAEV_18000191mg; Xp24d2; Xp24delta2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100009296, 10972, 379442, 529761, 68581, 84599
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.95 mg/mL
Formulation: PBS with 30% glycerol and 0.1% sodium azide
Gene Accession No.: P49755, Q28735, Q5E971, Q63584, Q9D1D4
Gene Symbols: TMED10, tmed10.L
Immunogen: Synthetic internal peptide corresponding to residues 50-150 of the human TMP21 protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Bovine, Human, Mouse, Non-human Primate, Rabbit, Rat, X. laevis
Product Type: Antibody
Isotype: IgG
Antigen:
TMP21
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TMED10
Gene Alias:
1110014C03Rik; 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein; hypothetical protein; integral membrane protein p23; integral membrane protein Tmp21-I (p23); p23; p24 family protein delta-1; P24(DELTA); p24d1; p24delta; p24delta1; S31I125; S31III125; testicular tissue protein Li 206; tmed10; tmed10.L; TMP21; Tmp-21-I; transmembrane emp24 domain-containing protein 10; transmembrane emp24-like trafficking protein 10; transmembrane emp24-like trafficking protein 10 (yeast); transmembrane p24 trafficking protein 10; transmembrane p24 trafficking protein 10 L homeolog; transmembrane protein; transmembrane protein tmp21; transmembrane trafficking protein; transmembrane trafficking protein 21; XELAEV_18000191mg; Xp24d2; Xp24delta2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100009296, 10972, 379442, 529761, 68581, 84599
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.95 mg/mL
Formulation:
PBS with 30% glycerol and 0.1% sodium azide
Gene Accession No.:
P49755, Q28735, Q5E971, Q63584, Q9D1D4
Gene Symbols:
TMED10, tmed10.L
Immunogen:
Synthetic internal peptide corresponding to residues 50-150 of the human TMP21 protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Mouse, Non-human Primate, Rabbit, Rat, X. laevis
Product Type:
Antibody
Isotype:
IgG
Antigen: Golgi protein 58k
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ftcd
Gene Alias: 58 kDa microtubule-binding protein; Formimidoyltetrahydrofolate cyclodeaminase; formimidoyltransferase cyclodeaminase; Formimidoyltransferase-cyclodeaminase; Formiminotetrahydrofolate cyclodeaminase; formiminotransferase cyclodeaminase; formiminotransferase-cyclodeaminase; FTCD; Glutamate formimidoyltransferase; Glutamate formiminotransferase; Glutamate formyltransferase; I79_006831; LCHC1
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 10841, 14317, 397517
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: O95954, P53603, Q91XD4
Gene Symbols: Ftcd
Immunogen: Internal sequence corresponding to amino acids CLREQGRGKDQPGRL.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Porcine
Product Type: Antibody
Isotype: IgG
Antigen:
Golgi protein 58k
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ftcd
Gene Alias:
58 kDa microtubule-binding protein; Formimidoyltetrahydrofolate cyclodeaminase; formimidoyltransferase cyclodeaminase; Formimidoyltransferase-cyclodeaminase; Formiminotetrahydrofolate cyclodeaminase; formiminotransferase cyclodeaminase; formiminotransferase-cyclodeaminase; FTCD; Glutamate formimidoyltransferase; Glutamate formiminotransferase; Glutamate formyltransferase; I79_006831; LCHC1
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
10841, 14317, 397517
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O95954, P53603, Q91XD4
Gene Symbols:
Ftcd
Immunogen:
Internal sequence corresponding to amino acids CLREQGRGKDQPGRL.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Porcine
Product Type:
Antibody
Isotype:
IgG
Antigen: ERAB
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HSD17B10
Gene Alias: 17-beta-HSD 10; 17-beta-hydroxysteroid dehydrogenase 10; 17bHSD10; 17b-HSD10; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3-hydroxyacyl-CoA dehydrogenase type-2; ABAD; AB-binding alcohol dehydrogenase; Ads9; amyloid beta-peptide binding protein; amyloid-beta peptide binding alcohol dehydrogenase; CAMR; DUPXp11.22; endoplasmic reticulum-associated amyloid beta-peptide-binding protein; ERAB; HADH2; HADH2 protein; HCD2; HSD17B10; hydroxyacyl-Coenzyme A dehydrogenase type II; hydroxyacyl-Coenzyme A dehydrogenase, type II; hydroxysteroid (17-beta) dehydrogenase 10; hydroxysteroid 17-beta dehydrogenase 10; hydroxysteroid dehydrogenase 10; MHBD; mitochondrial ribo; Mitochondrial ribonuclease P protein 2; mitochondrial RNas; mitochondrial RNase P protein 2; mitochondrial RNase P subunit 2; MRPP2; MRX17; MRX31; MRXS10; RP3-339A18.2; SCHAD; SDR5C1; Short chain dehydrogenase/reductase family 5C member 1; short
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 3028
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q99714
Gene Symbols: HSD17B10
Immunogen: Synthetic peptide corresponding to the C terminus amino acids CIRLDGAIRMQP.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ERAB
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HSD17B10
Gene Alias:
17-beta-HSD 10; 17-beta-hydroxysteroid dehydrogenase 10; 17bHSD10; 17b-HSD10; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3-hydroxyacyl-CoA dehydrogenase type-2; ABAD; AB-binding alcohol dehydrogenase; Ads9; amyloid beta-peptide binding protein; amyloid-beta peptide binding alcohol dehydrogenase; CAMR; DUPXp11.22; endoplasmic reticulum-associated amyloid beta-peptide-binding protein; ERAB; HADH2; HADH2 protein; HCD2; HSD17B10; hydroxyacyl-Coenzyme A dehydrogenase type II; hydroxyacyl-Coenzyme A dehydrogenase, type II; hydroxysteroid (17-beta) dehydrogenase 10; hydroxysteroid 17-beta dehydrogenase 10; hydroxysteroid dehydrogenase 10; MHBD; mitochondrial ribo; Mitochondrial ribonuclease P protein 2; mitochondrial RNas; mitochondrial RNase P protein 2; mitochondrial RNase P subunit 2; MRPP2; MRX17; MRX31; MRXS10; RP3-339A18.2; SCHAD; SDR5C1; Short chain dehydrogenase/reductase family 5C member 1; short
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
3028
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q99714
Gene Symbols:
HSD17B10
Immunogen:
Synthetic peptide corresponding to the C terminus amino acids CIRLDGAIRMQP.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ADAM17
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ADAM17
Gene Alias: a disintegrin and metallopeptidase domain 17; a disintegrin and metalloprotease domain 17; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 17; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADAM; ADAM 17; ADAM metallopeptidase domain 17; ADAM metallopeptidase domain 18; Adam17; ADAM18; ADAMs; CD156B; CD156b antigen; CSVP; Disintegrin and metalloproteinase domain-containing protein 17; metalloendopeptidases; NISBD; NISBD1; Snake venom-like protease; TACE; TNF-alpha convertase; TNF-alpha converting enzyme; TNF-alpha-converting enzyme; tumor necrosis factor, alpha, converting enzyme
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 6868
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: P78536
Gene Symbols: ADAM17
Immunogen: Synthetic peptide corresponding to the C terminus amino acids LQRQNRVDSKETEC.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ADAM17
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ADAM17
Gene Alias:
a disintegrin and metallopeptidase domain 17; a disintegrin and metalloprotease domain 17; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 17; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADAM; ADAM 17; ADAM metallopeptidase domain 17; ADAM metallopeptidase domain 18; Adam17; ADAM18; ADAMs; CD156B; CD156b antigen; CSVP; Disintegrin and metalloproteinase domain-containing protein 17; metalloendopeptidases; NISBD; NISBD1; Snake venom-like protease; TACE; TNF-alpha convertase; TNF-alpha converting enzyme; TNF-alpha-converting enzyme; tumor necrosis factor, alpha, converting enzyme
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
6868
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P78536
Gene Symbols:
ADAM17
Immunogen:
Synthetic peptide corresponding to the C terminus amino acids LQRQNRVDSKETEC.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG