01-674-652
MELK Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-652-Each-of-1 | In Stock | ₹ 44,705.10 |
01-674-652 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
MELK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MELK
Gene Alias
AI327312; hMELK; HPK38; Kiaa0175; Maternal embryonic leucine zipper kinase; Melk; mKIAA0175; MPK38; OTTHUMP00000046113; pEg3 kinase; Pk38; Protein kinase Eg3; protein kinase PK38; RP11-8N6.1; Tyrosine-protein kinase MELK
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
9833
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q14680
Gene Symbols
MELK
Immunogen
Synthetic peptide corresponding to the C terminus amino acids KRLVEDILSSCKV.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with bovine, canine and mouse based on sequence homology
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000
- MELK is a serine/threonione kinase which is related to the AMPK family that has been linked to the cell cycle
- MELK has also been shown to be overexpressed in cancer and has been identified has a potential target for cancer therapeutics
- MELK has a broad substrate specificity; phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622
- Acts as an activator of apoptosis by phosphorylating and activating MAP3K5/ASK1
- Acts as a regulator of cell cycle, notably by mediating phosphorylation of CDC25B, promoting localization of CDC25B to the centrosome and the spindle poles during mitosis
- Plays a key role in cell proliferation and carcinogenesis
- Required for proliferation of embryonic and postnatal multipotent neural progenitors
- Phosphorylates and inhibits BCL2L14, possibly leading to affect mammary carcinogenesis by mediating inhibition of the pro-apoptotic function of BCL2L14
- Also involved in the inhibition of spliceosome assembly during mitosis by phosphorylating ZNF622, thereby contributing to its redirection to the nucleus
- May also play a role in primitive hematopoiesis.
Compare Similar Items
Show Difference
Antigen: MELK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MELK
Gene Alias: AI327312; hMELK; HPK38; Kiaa0175; Maternal embryonic leucine zipper kinase; Melk; mKIAA0175; MPK38; OTTHUMP00000046113; pEg3 kinase; Pk38; Protein kinase Eg3; protein kinase PK38; RP11-8N6.1; Tyrosine-protein kinase MELK
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 9833
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q14680
Gene Symbols: MELK
Immunogen: Synthetic peptide corresponding to the C terminus amino acids KRLVEDILSSCKV.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MELK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MELK
Gene Alias:
AI327312; hMELK; HPK38; Kiaa0175; Maternal embryonic leucine zipper kinase; Melk; mKIAA0175; MPK38; OTTHUMP00000046113; pEg3 kinase; Pk38; Protein kinase Eg3; protein kinase PK38; RP11-8N6.1; Tyrosine-protein kinase MELK
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
9833
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q14680
Gene Symbols:
MELK
Immunogen:
Synthetic peptide corresponding to the C terminus amino acids KRLVEDILSSCKV.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: p47phox
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ncf1
Gene Alias: 47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NADPH oxidase organizer 2; NADPH oxidase subunit (47 kD); NADPH oxidase subunit (47kDa); Ncf1; NCF-1; NCF1A; NCF-47K; neutrop; neutrophil cytosol factor 1; neutrophil cytosolic factor 1; neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1); neutrophil NADPH oxidase factor 1; Nox organizer 2; NOXO2; nox-organizing protein 2; P47 phox; p47<phox>; p47phox; p47-phox; phagocyte oxidase 47 kDa; SH3 and PX domain-containing protein 1A; SH3PXD1A
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 100134857, 17969, 653361
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: P14598, Q09014
Gene Symbols: Ncf1
Immunogen: Synthetic peptide corresponding to the C terminus amino acids SESTKRKLASAV
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Porcine
Product Type: Antibody
Isotype: IgG
Antigen:
p47phox
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ncf1
Gene Alias:
47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NADPH oxidase organizer 2; NADPH oxidase subunit (47 kD); NADPH oxidase subunit (47kDa); Ncf1; NCF-1; NCF1A; NCF-47K; neutrop; neutrophil cytosol factor 1; neutrophil cytosolic factor 1; neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1); neutrophil NADPH oxidase factor 1; Nox organizer 2; NOXO2; nox-organizing protein 2; P47 phox; p47<phox>; p47phox; p47-phox; phagocyte oxidase 47 kDa; SH3 and PX domain-containing protein 1A; SH3PXD1A
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
100134857, 17969, 653361
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P14598, Q09014
Gene Symbols:
Ncf1
Immunogen:
Synthetic peptide corresponding to the C terminus amino acids SESTKRKLASAV
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Porcine
Product Type:
Antibody
Isotype:
IgG
Antigen: PAI1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Serpine1
Gene Alias: Endothelial plasminogen activator inhibitor; nexin, plasminogen activator inhibitor type 1; PAI; PAI1; PAI-1; PAI1 protein; PAI1A; Pai1aa; Planh; Planh1; plas; plasminogen activator inhibitor; plasminogen activator inhibitor 1; plasminogen activator inhibitor I; plasminogen activator inhibitor, type I; plasminogen activator inhibitor-1; Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI); putative plasminogen activator inhibitor-1; RATPAI1A; serine (or cysteine) peptidase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; serine (or cysteine) proteinase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, member 1; serpin E1; serpin family E member 1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; SERPINE1; SERPINE-1
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 5054
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: P05121
Gene Symbols: Serpine1
Immunogen: Synthetic peptide corresponding to amino acids C-GFKIDDKGMAPALRH, from the internal region of SERPINE1.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PAI1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Serpine1
Gene Alias:
Endothelial plasminogen activator inhibitor; nexin, plasminogen activator inhibitor type 1; PAI; PAI1; PAI-1; PAI1 protein; PAI1A; Pai1aa; Planh; Planh1; plas; plasminogen activator inhibitor; plasminogen activator inhibitor 1; plasminogen activator inhibitor I; plasminogen activator inhibitor, type I; plasminogen activator inhibitor-1; Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI); putative plasminogen activator inhibitor-1; RATPAI1A; serine (or cysteine) peptidase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; serine (or cysteine) proteinase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, member 1; serpin E1; serpin family E member 1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; SERPINE1; SERPINE-1
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
5054
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P05121
Gene Symbols:
Serpine1
Immunogen:
Synthetic peptide corresponding to amino acids C-GFKIDDKGMAPALRH, from the internal region of SERPINE1.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ERp57
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PDIA3
Gene Alias: 58 kDa glucose-regulated protein; 58 kDa microsomal protein; 58kDa; Disulfide isomerase ER-60; endoplasmic reticulum P58; endoplasmic reticulum protein; endoplasmic reticulum resident protein 57; Endoplasmic reticulum resident protein 60; epididymis secretory protein Li 269; epididymis secretory sperm binding protein Li 93n; ER p57; ER protein 57; ER protein 60; ER60; ER-60 protease; Erp; ERp 57; ERp57; ERP57 protein; ERP60; ERp61; glucose regulated protein 58; glucose regulated protein 58kD; glucose regulated protein, 58 kDa; glucose regulated protein, 58kDa; GRP 57; GRP 58; GRP57; Grp58; grp-58; HEL-S-269; HEL-S-93n; HIP-70; HsT17083; I79_003765; oxidoreductase ERp57; p58; PDI; PDIA 3; PDIA3; PDI-Q2; phospholipase C, alpha; phospholipase C-alpha; PI PLC; PI-PLC; PLC alpha; PLC[a]; Plca; protein disulfide isomerase associated 3; protein disulfide isomerase family A member 3; protein disulfide isomerase family A, member 3; protein disulfide isomerase-associated 3; protein disulfide-isomerase A3; Q-2
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 14827, 2923
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: P27773, P30101
Gene Symbols: PDIA3
Immunogen: Synthetic peptide corresponding to the C terminus residues E E K P K K K K K A Q E D L of PDIA3.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
ERp57
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PDIA3
Gene Alias:
58 kDa glucose-regulated protein; 58 kDa microsomal protein; 58kDa; Disulfide isomerase ER-60; endoplasmic reticulum P58; endoplasmic reticulum protein; endoplasmic reticulum resident protein 57; Endoplasmic reticulum resident protein 60; epididymis secretory protein Li 269; epididymis secretory sperm binding protein Li 93n; ER p57; ER protein 57; ER protein 60; ER60; ER-60 protease; Erp; ERp 57; ERp57; ERP57 protein; ERP60; ERp61; glucose regulated protein 58; glucose regulated protein 58kD; glucose regulated protein, 58 kDa; glucose regulated protein, 58kDa; GRP 57; GRP 58; GRP57; Grp58; grp-58; HEL-S-269; HEL-S-93n; HIP-70; HsT17083; I79_003765; oxidoreductase ERp57; p58; PDI; PDIA 3; PDIA3; PDI-Q2; phospholipase C, alpha; phospholipase C-alpha; PI PLC; PI-PLC; PLC alpha; PLC[a]; Plca; protein disulfide isomerase associated 3; protein disulfide isomerase family A member 3; protein disulfide isomerase family A, member 3; protein disulfide isomerase-associated 3; protein disulfide-isomerase A3; Q-2
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
14827, 2923
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P27773, P30101
Gene Symbols:
PDIA3
Immunogen:
Synthetic peptide corresponding to the C terminus residues E E K P K K K K K A Q E D L of PDIA3.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG