01-674-792
BUBR1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-792-Each-of-1 | In Stock | ₹ 44,705.10 |
01-674-792 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
BUBR1
Classification
Polyclonal
Formulation
PBS with 0.08% sodium azide
Gene Accession No.
Q9Z1S0
Gene Symbols
BUB1B
Immunogen
Recombinant protein corresponding to residues 232-603 of mouse Bub1b.
Quantity
250 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry, Western Blot
Conjugate
Unconjugated
Gene
BUB1B
Gene Alias
AU045529; BUB1 budding uninhibited by benzimidazoles 1 homolog beta; BUB1 mitotic checkpoint serine/threonine kinase B; Bub1A; Bub1b; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 beta; budding uninhibited by benzimidazoles 1 homolog beta; budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae); hBub1; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; Mitotic checkpoint kinase MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; Protein SSK1; SSK1
Host Species
Sheep
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
12236
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- A suggested positive control for this product is mitotic NIH-3T3 cells
- BUBR1 is a member of the Ser/Thr protein kinase family
- It is a component of the mitotic checkpoint that delays anaphase until all chromosome are properly attached to the mitotic spindle
- Compromised spindle checkpoints are thought to play an important role in genetic instability that predisposes cells to malignant transformations
- Human cells contain two related checkpoint protein kinases, evolved from the BUB1 gene; hBUBR1 and hBUB1
- They are important components of the spindle checkpoint Both kinases monitor mitotic kinetochore-microtubule interactions
- hBUBR1 is essential for normal mitotic progression as it prevents cells from entering into anaphase too early
- BUBR1 has been detected in human cancers
- It has been identified as a novel binding partner of BCSG1 (Breast Cancer-Specific Gene 1), which has been suggested to accelerate the progression of breast cancer by compromising the mitotic checkpoint control through inactivation of BUBR1.
Compare Similar Items
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Antigen: BUBR1
Classification: Polyclonal
Formulation: PBS with 0.08% sodium azide
Gene Accession No.: Q9Z1S0
Gene Symbols: BUB1B
Immunogen: Recombinant protein corresponding to residues 232-603 of mouse Bub1b.
Quantity: 250 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry, Western Blot
Conjugate: Unconjugated
Gene: BUB1B
Gene Alias: AU045529; BUB1 budding uninhibited by benzimidazoles 1 homolog beta; BUB1 mitotic checkpoint serine/threonine kinase B; Bub1A; Bub1b; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 beta; budding uninhibited by benzimidazoles 1 homolog beta; budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae); hBub1; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; Mitotic checkpoint kinase MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; Protein SSK1; SSK1
Host Species: Sheep
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 12236
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
BUBR1
Classification:
Polyclonal
Formulation:
PBS with 0.08% sodium azide
Gene Accession No.:
Q9Z1S0
Gene Symbols:
BUB1B
Immunogen:
Recombinant protein corresponding to residues 232-603 of mouse Bub1b.
Quantity:
250 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry, Western Blot
Conjugate:
Unconjugated
Gene:
BUB1B
Gene Alias:
AU045529; BUB1 budding uninhibited by benzimidazoles 1 homolog beta; BUB1 mitotic checkpoint serine/threonine kinase B; Bub1A; Bub1b; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 beta; budding uninhibited by benzimidazoles 1 homolog beta; budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae); hBub1; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; Mitotic checkpoint kinase MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; Protein SSK1; SSK1
Host Species:
Sheep
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
12236
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Farnesyl
Classification: Polyclonal
Formulation: PBS with 0.08% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: Farnesyl cysteine conjugated to KLH
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Chemical
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry
Conjugate: Unconjugated
Gene: __
Gene Alias: __
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Farnesyl
Classification:
Polyclonal
Formulation:
PBS with 0.08% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Farnesyl cysteine conjugated to KLH
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Chemical
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
__
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: LPAR3
Classification: Polyclonal
Formulation: PBS with 0.08% sodium azide
Gene Accession No.: Q9UBY5
Gene Symbols: Lpar3
Immunogen: Synthetic peptide corresponding to the C-terminal of human EDG7.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: Lpar3
Gene Alias: calcium-mobilizing lysophosphatidic acid receptor LP-A3; Edg7; Edg-7; endothelial cell differentiation gene 7; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 7; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7; GPCR; HOFNH30; LPA receptor 3; LPA receptor EDG7; lpA3; LP-A3; LPA-3; LPA3 Receptor; Lpar3; Lysophosphatidic acid receptor 3; lysophosphatidic acid receptor Edg-7; putative G protein-coupled receptor snGPCR32; RP4-678I3; snGPCR32
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 23566
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
LPAR3
Classification:
Polyclonal
Formulation:
PBS with 0.08% sodium azide
Gene Accession No.:
Q9UBY5
Gene Symbols:
Lpar3
Immunogen:
Synthetic peptide corresponding to the C-terminal of human EDG7.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
Lpar3
Gene Alias:
calcium-mobilizing lysophosphatidic acid receptor LP-A3; Edg7; Edg-7; endothelial cell differentiation gene 7; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 7; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7; GPCR; HOFNH30; LPA receptor 3; LPA receptor EDG7; lpA3; LP-A3; LPA-3; LPA3 Receptor; Lpar3; Lysophosphatidic acid receptor 3; lysophosphatidic acid receptor Edg-7; putative G protein-coupled receptor snGPCR32; RP4-678I3; snGPCR32
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
23566
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: RIT1
Classification: Polyclonal
Formulation: PBS with 0.08% sodium azide
Gene Accession No.: Q92963
Gene Symbols: RIT1
Immunogen: His-tagged recombinant human Rit protein.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: RIT1
Gene Alias: GTP-binding protein Rit1; GTP-binding protein Roc1; MGC125864; MGC125865; NS8; Ras like without CAAX 1; ras-like protein expressed in many tissues; Ras-like without CAAX 1; ras-like without CAAX protein 1; RGD1559874; RIBB; Ric-like, expressed in many tissues; RIT; RIT1; ROC1; si:ch211-93a2.3
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 6016
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
RIT1
Classification:
Polyclonal
Formulation:
PBS with 0.08% sodium azide
Gene Accession No.:
Q92963
Gene Symbols:
RIT1
Immunogen:
His-tagged recombinant human Rit protein.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
RIT1
Gene Alias:
GTP-binding protein Rit1; GTP-binding protein Roc1; MGC125864; MGC125865; NS8; Ras like without CAAX 1; ras-like protein expressed in many tissues; Ras-like without CAAX 1; ras-like without CAAX protein 1; RGD1559874; RIBB; Ric-like, expressed in many tissues; RIT; RIT1; ROC1; si:ch211-93a2.3
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
6016
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid