01-675-689

TAK1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-675-689-Each-of-1 In Stock ₹ 44,790.66

01-675-689 - Each of 1

₹ 44,790.66

In Stock

Quantity

1

Base Price: ₹ 44,790.66

GST (18%): ₹ 8,062.319

Total Price: ₹ 52,852.979

Antigen

TAK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAP3K7

Gene Alias

B430101B05; C87327; hypothetical protein LOC553788; I79_000697; M3K7; map3k7; map3k7.L; MAPKKK; MEKK7; mitogen activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7 L homeolog; RP1-154G14.1; si:ch211-225h9.1; Tak1; TAK1z; TGF1a; TGF-beta activated kinase 1; TGF-beta-activated kinase 1; TGF-beta-activated kinase TAK1; transforming growth factor beta-activated kinase 1; transforming growth factor-beta-activated kinase 1; XELAEV_18027270mg; xTAK1; zgc:110612

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

26409, 6885

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.

O43318, Q62073

Gene Symbols

MAP3K7

Immunogen

Synthetic peptide corresponding to residues 19-35 and 564-579 of human TaK1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Suggested positive control: NIH-3T3 whole cell lysates
  • TAK1 (also known as MAP3K7), a part of the serine/threonine kinase family, is a versatile protein with many signaling functions
  • Originally identified as a TGF- beta-activated kinase, TAK1 interacts with TGF- beta-receptor and TRAF6 to modulate TGF- beta activation of JNK and p38
  • It has additional roles in activation of p38 and JNK through Wnt, BMP, and activin signaling pathways as well in response to thyroid hormone, osmotic stress, endothelin, and ephrine
  • Through activation of von Hippel-Lindau tumor suppressor expression, TAK1 represses PDGF-B, integrin beta1 and integrin beta5, promoting proper wound healing
  • TAK1 also plays an essential role in IKK activation in numerous signaling pathways including IL-1, IL-6, IL-18, TNF, CD40, TLR, and RIG-I
  • Activation of the TAK1-IKK pathway requires TAB2/3 and ubiquitination
  • In this process, TAB2/3 binds to the C-terminal region of TAK1 and becomes polyubiquitinated, TAK1 is autophosphorylated at Thr178, Thr184, Thr187 and Ser192, and finally TAK1 phosphorylates IKK- beta
  • Additionally, TAK1 represses human telomerase reverse transcriptase suggesting a role in regulation of cell lifespan.

Compare Similar Items

Show Difference

Img

Thermo Scientific

01-675-689

--


Antigen:
TAK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP3K7

Gene Alias:
B430101B05; C87327; hypothetical protein LOC553788; I79_000697; M3K7; map3k7; map3k7.L; MAPKKK; MEKK7; mitogen activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7 L homeolog; RP1-154G14.1; si:ch211-225h9.1; Tak1; TAK1z; TGF1a; TGF-beta activated kinase 1; TGF-beta-activated kinase 1; TGF-beta-activated kinase TAK1; transforming growth factor beta-activated kinase 1; transforming growth factor-beta-activated kinase 1; XELAEV_18027270mg; xTAK1; zgc:110612

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
26409, 6885

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
O43318, Q62073

Gene Symbols:
MAP3K7

Immunogen:
Synthetic peptide corresponding to residues 19-35 and 564-579 of human TaK1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-675-691

--


Antigen:
PRMT4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Carm1

Gene Alias:
Carm1; coactivator associated arginine methyltransferase 1; coactivator-associated arginine methyltransferase 1; coactivator-associated arginine methyltransferase 1 variant 5; histone-arginine methyltransferase CARM1; PRMT4; protein arginine methyltransferase; protein arginine N-methyltransferase 4

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10498

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
Q86X55

Gene Symbols:
Carm1

Immunogen:
Synthetic peptides coorresponding to residues 45-69 and 595-608 of human PRMT4.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-675-693

--


Antigen:
Dnmt2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRDMT1

Gene Alias:
DMNT2; DNA (cytosine-5)-methyltransferase-like protein 2; DNA cytosine-5 methyltransferase 2; DNA methyltransferase 2; DNA methyltransferase homolog HsaIIP; DNA methyltransferase homolog MmuIIP; DNA methyltransferase-2; DNA MTase homolog HsaIIP; DNA MTase homolog MmuIIP; Dnmt2; M.HsaIIP; m.MmuIIP; Met2; met-2; MHSAIIP; PUMET; RNMT1; Rnmt2; RP11-406H21.1; Trdmt1; tRNA (cytosine(38)-C(5))-methyltransferase; tRNA (cytosine-5-)-methyltransferase; tRNA aspartic acid methyltransferase 1

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
13434, 1787

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
O14717, O55055

Gene Symbols:
TRDMT1

Immunogen:
Synthetic peptides corresponding to residues 39-53 and 361-376 of mouse Dnmt2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-675-695

--


Antigen:
TRAF3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRAF3

Gene Alias:
AI528849; amn; CAP1; CAP-1; CD40 associated protein 1; CD40 binding protein; CD40 receptor associated factor 1; CD40 receptor-associated factor 1; CD40-binding protein; CD40BP; CRAF1; IIAE5; LAP1; LMP1-associated protein 1; RING-type E3 ubiquitin transferase TRAF3; T-BAM; TNF receptor associated factor 3; Tnf receptor-associated factor 3; TRAF3; Trafamn

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
22031, 7187

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
Q13114, Q60803

Gene Symbols:
TRAF3

Immunogen:
A peptide corresponding to amino acids between 300 and 350 of human TRAF3

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG