01-675-790

SPHK2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-675-790-Each-of-1 In Stock ₹ 47,015.22

01-675-790 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

SPHK2

Classification

Polyclonal

Formulation

PBS with 0.08% sodium azide

Gene Accession No.

Q9NRA0

Gene Symbols

Sphk2

Immunogen

Synthetic peptide corresponding to the N-terminal extension of Sphk2-L.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Gene

Sphk2

Gene Alias

C76851; SK 2; SK2; SK-2; Sphingosine kinase 2; sphingosine kinase type 2; Sphk2; SPK 2; SPK-2; Spk2, Sk2

Host Species

Rabbit

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

56848

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • A suggested positive control for this product is HEK-293 cells
  • SPHK2, along with SPHK1, catalyzes the phosphorylation of sphingosine producing the signaling molecule sphingosine-1-phosphate (S1P)
  • S1P signals through G-protein coupled receptors and controls diverse cellular processes
  • Inhibitors of SPHKs are viewed as potential therapeutics for the treatment of cancer
  • SPHK2 is an important signaling molecule with intra- and extracellular functions and has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis
  • The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors)
  • These receptors couple to multiple G proteins (e.g
  • S1P1 couples to Gi whereas S1P2 and S1P3 couple to Gq, G13 in addition to Gi) and regulate a extremely wide raange of cellular events including cell motility, survival, apoptosis, migration and cell-cell interaction
  • Important roles for S1P have also been reported in regulation of cardiogenesis, vascular maturation, oocyte survival, immune cell trafficking, cells of the neuronal system and bone cells
  • S1P levels are regulated by the activity of Sphk (Sphk1 and Sphk2).

Compare Similar Items

Show Difference

Img

Thermo Scientific

01-675-790

--


Antigen:
SPHK2

Classification:
Polyclonal

Formulation:
PBS with 0.08% sodium azide

Gene Accession No.:
Q9NRA0

Gene Symbols:
Sphk2

Immunogen:
Synthetic peptide corresponding to the N-terminal extension of Sphk2-L.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Gene:
Sphk2

Gene Alias:
C76851; SK 2; SK2; SK-2; Sphingosine kinase 2; sphingosine kinase type 2; Sphk2; SPK 2; SPK-2; Spk2, Sk2

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
56848

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

01-675-802

--


Antigen:
IRF7

Classification:
Polyclonal

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q92985, P70434

Gene Symbols:
IRF7

Immunogen:
Peptide corresponding to 14 residues from near the C-terminus of human IRF7.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
IRF7

Gene Alias:
IRF-7H, IRF7A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
293624, 3665, 54123

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

01-675-803

--


Antigen:
IRF7

Classification:
Polyclonal

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q92985

Gene Symbols:
IRF7

Immunogen:
Peptide corresponding to 14 residues near the center of human IRF7.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
IRF7

Gene Alias:
IRF-7H, IRF7A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3665

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

01-675-805

--


Antigen:
MD-1

Classification:
Polyclonal

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O95711, O88188

Gene Symbols:
LY86

Immunogen:
Synthetic peptide corresponding to 15 residues from near the center of human MD-1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
LY86

Gene Alias:
MD-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17084, 291359, 9450

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid