01-675-852

SPHK2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-675-852-Each-of-1 In Stock ₹ 47,015.22

01-675-852 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

SPHK2

Classification

Polyclonal

Formulation

PBS with 0.08% sodium azide

Gene Accession No.

Q9NRA0

Gene Symbols

Sphk2

Immunogen

Synthetic peptide corresponding to the N-terminal extension of Sphingosine Kinase 2-L.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Gene

Sphk2

Gene Alias

C76851; SK 2; SK2; SK-2; Sphingosine kinase 2; sphingosine kinase type 2; Sphk2; SPK 2; SPK-2; Spk2, Sk2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

56848

Content And Storage

-80° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • A suggested positive control for this product is Jurkat cell lysate
  • SPHK2, along with SPHK1, catalyzes the phosphorylation of sphingosine producing the signaling molecule sphingosine-1-phosphate (S1P)
  • S1P signals through G-protein coupled receptors and controls diverse cellular processes
  • Inhibitors of SPHKs are viewed as potential therapeutics for the treatment of cancer
  • SPHK2 is an important signaling molecule with intra- and extracellular functions and has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis
  • The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors)
  • These receptors couple to multiple G proteins (e.g
  • S1P1 couples to Gi whereas S1P2 and S1P3 couple to Gq, G13 in addition to Gi) and regulate a extremely wide raange of cellular events including cell motility, survival, apoptosis, migration and cell-cell interaction
  • Important roles for S1P have also been reported in regulation of cardiogenesis, vascular maturation, oocyte survival, immune cell trafficking, cells of the neuronal system and bone cells
  • S1P levels are regulated by the activity of Sphk (Sphk1 and Sphk2).

Compare Similar Items

Show Difference

Img

Thermo Scientific

01-675-852

--


Antigen:
SPHK2

Classification:
Polyclonal

Formulation:
PBS with 0.08% sodium azide

Gene Accession No.:
Q9NRA0

Gene Symbols:
Sphk2

Immunogen:
Synthetic peptide corresponding to the N-terminal extension of Sphingosine Kinase 2-L.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Gene:
Sphk2

Gene Alias:
C76851; SK 2; SK2; SK-2; Sphingosine kinase 2; sphingosine kinase type 2; Sphk2; SPK 2; SPK-2; Spk2, Sk2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56848

Content And Storage:
-80° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

01-675-859

--


Antigen:
Mouse IgG2a

Classification:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
White blood cells

Quantity:
100 Tests

Primary or Secondary:
Isotype Control (Primary)

Target Species:
Not Applicable

Product Type:
__

Isotype:
IgG2a κ

Applications:
Control, Flow Cytometry

Conjugate:
FITC

Gene:
__

Gene Alias:
IgG2, IgG2a

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-675-863

--


Antigen:
Mouse IgG1

Classification:
__

Formulation:
PBS with 0.08% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
White blood cells.

Quantity:
100 μg

Primary or Secondary:
Isotype Control (Primary)

Target Species:
Not Applicable

Product Type:
__

Isotype:
IgG1

Applications:
Control, Flow Cytometry

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
IgG1; Igh-4; Ighg1; Immunoglobulin G; Immunoglobulin G1; immunoglobulin heavy constant gamma 1 (G1m marker); ImmunoglobulinG; ImmunoglobulinG1; VH7183

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

01-675-864

--


Antigen:
Mouse IgG1

Classification:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
White blood cells.

Quantity:
100 Tests

Primary or Secondary:
Isotype Control (Primary)

Target Species:
Not Applicable

Product Type:
__

Isotype:
IgG1 κ

Applications:
Control, Flow Cytometry

Conjugate:
FITC

Gene:
__

Gene Alias:
IgG1

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid