01-675-838
NOTUM Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-675-838-Each-of-1 | In Stock | ₹ 47,015.22 |
01-675-838 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
NOTUM
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NOTUM
Gene Alias
[Wnt protein] O-palmitoleoyl-L-serine hydrolase; 5730593N15Rik; hNOTUM; NOTUM; notum pectinacetylesterase homolog; notum pectinacetylesterase homolog (Drosophila); NOTUM, palmitoleoyl-protein carboxylesterase; OK/SW-CL.30; Palmitoleoyl-protein carboxylesterase NOTUM; protein notum homolog; RGD1307119
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
147111, 77583
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.08% sodium azide
Gene Accession No.
Q6P988, Q8R116
Gene Symbols
NOTUM
Immunogen
Recombinant full-length notum protein from mouse.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control for this product is HepG2 cell lysate
- Genetic studies in Drosophila have revealed a novel secreted antagonist for Wingless (Wg) signaling, referred to as Notum/Wingful (Wf)
- Wf/Notum encodes a protein of 430 amino acid residues, which is related to plant pectin acetylesterases of the a/beta-hydrolase superfamily
- The main target of Notum action appears to be cell surface proteoglycans Dally and/or Dally-like (Dlp)
- Notum governs the extracellular Wg morphogen distribution via Dally and Dlp
- Also, like some vertebrate Wnt antagonists, notum expression is activated by Wg signaling, revealing the existence of a feedback control mechanism in which Wg modifies its own gradient distribution
- In vertebrate, proteoglycans related to Dally and Dlp likely play important roles in Wnt signaling which encodes a glypican that is required for Wnt-11 signaling
- A single ortholog of Notum exists in the mouse and the human genome, implying that a similar regulatory mechanism may exist in vertebrates.
Compare Similar Items
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Antigen: NOTUM
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NOTUM
Gene Alias: [Wnt protein] O-palmitoleoyl-L-serine hydrolase; 5730593N15Rik; hNOTUM; NOTUM; notum pectinacetylesterase homolog; notum pectinacetylesterase homolog (Drosophila); NOTUM, palmitoleoyl-protein carboxylesterase; OK/SW-CL.30; Palmitoleoyl-protein carboxylesterase NOTUM; protein notum homolog; RGD1307119
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 147111, 77583
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.08% sodium azide
Gene Accession No.: Q6P988, Q8R116
Gene Symbols: NOTUM
Immunogen: Recombinant full-length notum protein from mouse.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
NOTUM
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NOTUM
Gene Alias:
[Wnt protein] O-palmitoleoyl-L-serine hydrolase; 5730593N15Rik; hNOTUM; NOTUM; notum pectinacetylesterase homolog; notum pectinacetylesterase homolog (Drosophila); NOTUM, palmitoleoyl-protein carboxylesterase; OK/SW-CL.30; Palmitoleoyl-protein carboxylesterase NOTUM; protein notum homolog; RGD1307119
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
147111, 77583
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.08% sodium azide
Gene Accession No.:
Q6P988, Q8R116
Gene Symbols:
NOTUM
Immunogen:
Recombinant full-length notum protein from mouse.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: SULF2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SULF2
Gene Alias: 2010004N24Rik; AU020235; DKFZp313E091; Extracellular sulfatase Sulf-2; Extracellular sulfatase Sulf-2-like protein; FLJ44488; FLJ90554; HSULF-2; KIAA1247; MGC126411; mKIAA1247; mSulf-2; OTTHUMP00000031223; RP5-1049G16.1; SULF2; sulfatase 2; sulfatase FP2; UNQ559/PRO1120
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 55959
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.08% sodium azide
Gene Accession No.: Q8IWU5
Gene Symbols: SULF2
Immunogen: Synthetic peptide corresponding to human Sulf2.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SULF2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SULF2
Gene Alias:
2010004N24Rik; AU020235; DKFZp313E091; Extracellular sulfatase Sulf-2; Extracellular sulfatase Sulf-2-like protein; FLJ44488; FLJ90554; HSULF-2; KIAA1247; MGC126411; mKIAA1247; mSulf-2; OTTHUMP00000031223; RP5-1049G16.1; SULF2; sulfatase 2; sulfatase FP2; UNQ559/PRO1120
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
55959
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.08% sodium azide
Gene Accession No.:
Q8IWU5
Gene Symbols:
SULF2
Immunogen:
Synthetic peptide corresponding to human Sulf2.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SIAH1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SIAH1
Gene Alias: AA960570; AA982064; AI853500; E3 ubiquitin-protein ligase SIAH1; E3 ubiquitin-protein ligase SIAH1A; E3 ubiquitin-protein ligase SIAH1B; FLJ08065; h HUMSIAH; hSIAH1; HUMSIAH; mSiah-1a; RING-type E3 ubiquitin transferase SIAH1; RING-type E3 ubiquitin transferase SIAH1A; RING-type E3 ubiquitin transferase SIAH1B; seven in absentia 1A; seven in absentia 1B; seven in absentia homolog 1; Seven in absentia homolog 1a; Seven in absentia homolog 1b; SIAH; siah E3 ubiquitin protein ligase 1; SIAH1; siah-1; Siah1a; Siah-1a; Siah1b; siah-1b; Sinh1a; Sinh1b
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 6477
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.08% sodium azide
Gene Accession No.: Q8IUQ4
Gene Symbols: SIAH1
Immunogen: Synthetic peptide corresponding to human SIAH-1.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SIAH1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SIAH1
Gene Alias:
AA960570; AA982064; AI853500; E3 ubiquitin-protein ligase SIAH1; E3 ubiquitin-protein ligase SIAH1A; E3 ubiquitin-protein ligase SIAH1B; FLJ08065; h HUMSIAH; hSIAH1; HUMSIAH; mSiah-1a; RING-type E3 ubiquitin transferase SIAH1; RING-type E3 ubiquitin transferase SIAH1A; RING-type E3 ubiquitin transferase SIAH1B; seven in absentia 1A; seven in absentia 1B; seven in absentia homolog 1; Seven in absentia homolog 1a; Seven in absentia homolog 1b; SIAH; siah E3 ubiquitin protein ligase 1; SIAH1; siah-1; Siah1a; Siah-1a; Siah1b; siah-1b; Sinh1a; Sinh1b
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
6477
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.08% sodium azide
Gene Accession No.:
Q8IUQ4
Gene Symbols:
SIAH1
Immunogen:
Synthetic peptide corresponding to human SIAH-1.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SPARC
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SPARC
Gene Alias: Basement membrane protein 40, basement-membrane protein 40, BM40, BM-40, Cysteine rich protein, OI17, ON, Osteonectin, osteonectin precursor, Secreted acidic cystein rich glycoprotein, secreted acidic cysteine rich glycoprotein, Secreted acidic cystein-rich glycoprotein (osteonectin), secreted protein acidic and cysteine rich, secreted protein acidic and rich in cysteine, Secreted protein acidic and rich in cysteine (SPARC), secreted protein, acidic, cysteine-rich (osteonectin), secreted protein, acidic, cysteine-rich [osteonectin], SPARC
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 6678
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunohistochemistry, Western Blot
Concentration: __
Formulation: PBS with 0.08% sodium azide
Gene Accession No.: P09486
Gene Symbols: SPARC
Immunogen: Synthetic peptide corresponding to human SPARC.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SPARC
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SPARC
Gene Alias:
Basement membrane protein 40, basement-membrane protein 40, BM40, BM-40, Cysteine rich protein, OI17, ON, Osteonectin, osteonectin precursor, Secreted acidic cystein rich glycoprotein, secreted acidic cysteine rich glycoprotein, Secreted acidic cystein-rich glycoprotein (osteonectin), secreted protein acidic and cysteine rich, secreted protein acidic and rich in cysteine, Secreted protein acidic and rich in cysteine (SPARC), secreted protein, acidic, cysteine-rich (osteonectin), secreted protein, acidic, cysteine-rich [osteonectin], SPARC
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
6678
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Western Blot
Concentration:
__
Formulation:
PBS with 0.08% sodium azide
Gene Accession No.:
P09486
Gene Symbols:
SPARC
Immunogen:
Synthetic peptide corresponding to human SPARC.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG