01-675-881

CD20 Monoclonal Antibody (MEM-97), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-675-881-Each-of-1 In Stock ₹ 37,475.28

01-675-881 - Each of 1

₹ 37,475.28

In Stock

Quantity

1

Base Price: ₹ 37,475.28

GST (18%): ₹ 6,745.55

Total Price: ₹ 44,220.83

Antigen

CD20

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

P11836

Gene Symbols

Ms4a1

Immunogen

Burkitt's lymphoma cell line Raji.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Human

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunoprecipitation

Clone

MEM-97

Conjugate

Unconjugated

Gene

Ms4a1

Gene Alias

AA960661; APY; ATOPY; B1; B-cell differentiation antigen Ly-44; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; B-lymphocyte surface antigen B1; Bp35; Cd20; CD20 antigen; CD20 cell surface protein; CD20 receptor; CVID5; EGK_06167; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IGEL; IGER; IGHER; LEU16; LEU-16; Leukocyte surface antigen Leu-16; Ly44; Ly-44; Lymphocyte antigen 44; membrane spanning 4-domains A1; membrane-spanning 4-domains subfamily A member 1; membrane-spanning 4-domains, subfamily A, member 1; membrane-spanning 4-domains, subfamily A, member 2; MGC3969; MS4A1; MS4A2; S7

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

505653, 931

Content And Storage

4° C, do not freeze

Form

Liquid

Related Products

Img

Thermo Scientific

01-676-131

--

Img

Thermo Scientific

01-676-259

--

Img

Thermo Scientific

01-676-214

--

Img

Thermo Scientific

01-675-877

--

Img

Thermo Scientific

01-675-081

--

Img

Thermo Scientific

01-675-959

--

Img

Thermo Scientific

01-676-181

--

Img

Thermo Scientific

01-676-222

--

Description

  • CD20 is a non-glycosylated surface phosphoprotein that has a molecular weight range of 33-37 kDa depending on the degree of phosphorylation
  • CD20 is expressed on mature and most malignant B cells, in a subpopulation of T lymphocytes and follicular dendritic cells
  • CD20 expression on B cells is synchronous with the expression of surface IgM and it regulates transmembrane calcium conductance, cell cycle progression and B-cell proliferation
  • CD20 is also associated with lipid rafts, but the intensity of this association depends on extracellular triggering, employing CD20 conformational change, and/or BCR (B cell antigen receptor) aggregation
  • After the receptor ligation, BCR and CD20 colocalize and then rapidly dissociate before BCR endocytosis, whereas CD20 remains at the cell surface
  • CD20 serves as a useful target for antibody-mediated therapeutic depletion of B cells, as it is expressed at high levels on most B-cell malignancies, but does not become internalized or shed from the plasma membrane following monoclonal antibody treatment
  • Diseases associated with CD20 dysfunction include Ms4a1-related common variable immune deficiency.

Compare Similar Items

Show Difference

Img

Thermo Scientific

01-675-881

--


Antigen:
CD20

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
P11836

Gene Symbols:
Ms4a1

Immunogen:
Burkitt's lymphoma cell line Raji.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunoprecipitation

Clone:
MEM-97

Conjugate:
Unconjugated

Gene:
Ms4a1

Gene Alias:
AA960661; APY; ATOPY; B1; B-cell differentiation antigen Ly-44; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; B-lymphocyte surface antigen B1; Bp35; Cd20; CD20 antigen; CD20 cell surface protein; CD20 receptor; CVID5; EGK_06167; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IGEL; IGER; IGHER; LEU16; LEU-16; Leukocyte surface antigen Leu-16; Ly44; Ly-44; Lymphocyte antigen 44; membrane spanning 4-domains A1; membrane-spanning 4-domains subfamily A member 1; membrane-spanning 4-domains, subfamily A, member 1; membrane-spanning 4-domains, subfamily A, member 2; MGC3969; MS4A1; MS4A2; S7

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
505653, 931

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-675-882

--


Antigen:
CD43

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
P16150

Gene Symbols:
SPN

Immunogen:
Human T lymphocytes.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
MEM-59

Conjugate:
Unconjugated

Gene:
SPN

Gene Alias:
3E8 antigen; A630014B01Rik; B-cell differentiation antigen LP-3; CD43; CD43 cytoplasmic tail; CD43-ct; Galactoglycoprotein; GALGP; gpL115; Leukocyte sialoglycoprotein; leukosialin; leukosianin; LOC101120462; LOW QUALITY PROTEIN: leukosialin; Lsn; Lsn1; Ly48; Ly-48; Lymphocyte antigen 48; sialophorin; sialophorin (gpL115, leukosialin, CD43); sialophorin gpL115; SPN; W3/13 antigen

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6693

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-675-883

--


Antigen:
CD45

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P08575

Gene Symbols:
PTPRC

Immunogen:
Human thymocytes and T lymphocytes.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
MEM-28

Conjugate:
Unconjugated

Gene:
PTPRC

Gene Alias:
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-675-885

--


Antigen:
CD45RA

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P08575

Gene Symbols:
PTPRC

Immunogen:
Human thymocytes and T lymphocytes.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
MEM-56

Conjugate:
Unconjugated

Gene:
PTPRC

Gene Alias:
B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; Leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T100; T200; T200 glycoprotein; T200 leukocyte common antigen

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Content And Storage:
4° C, do not freeze

Form:
Liquid