01-675-885

CD45RA Monoclonal Antibody (MEM-56), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-675-885-Each-of-1 In Stock ₹ 30,202.68

01-675-885 - Each of 1

₹ 30,202.68

In Stock

Quantity

1

Base Price: ₹ 30,202.68

GST (18%): ₹ 5,436.482

Total Price: ₹ 35,639.162

Antigen

CD45RA

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

P08575

Gene Symbols

PTPRC

Immunogen

Human thymocytes and T lymphocytes.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

MEM-56

Conjugate

Unconjugated

Gene

PTPRC

Gene Alias

B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; Leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T100; T200; T200 glycoprotein; T200 leukocyte common antigen

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5788

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • This antibody has been sucessfully used in Mass Cytometry (CyTof)
  • Immunohistochemistry (Paraffin): No pre-treatment of tissue sections is needed
  • CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
  • CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes
  • CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
  • CD45 protein exists as multiple isoforms as a result of alternative splicing and these isoforms differ in their extracellular domains, however, they share identical transmembrane and cytoplasmic domains
  • CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
  • Besides the role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis
  • CD45 is expressed on cells of the human hematopoietic lineage, with the exception of mature red cells and is not detected on differentiated cells of other tissues
  • It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions
  • Diseases associated with CD45 dysfunction include severe combined immunodeficiency and Hepatitis C.

Compare Similar Items

Show Difference

Img

Thermo Scientific

01-675-885

--


Antigen:
CD45RA

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P08575

Gene Symbols:
PTPRC

Immunogen:
Human thymocytes and T lymphocytes.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
MEM-56

Conjugate:
Unconjugated

Gene:
PTPRC

Gene Alias:
B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; Leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T100; T200; T200 glycoprotein; T200 leukocyte common antigen

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-675-887

--


Antigen:
CD45RB

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P08575

Gene Symbols:
Ptprc

Immunogen:
Human thymocytes and T lymphocytes.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
MEM-55

Conjugate:
Unconjugated

Gene:
Ptprc

Gene Alias:
B220; CD45; CD45 antigen; CD45R; GP180; LCA; L-CA; Leukocyte common antigen; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; PTPRC; Receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein; T200 leukocyte common antigen

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-675-889

--


Antigen:
CD47

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 15mM sodium azide; pH 8

Gene Accession No.:
Q08722, Q9GKE8

Gene Symbols:
CD47

Immunogen:
COS-7 (African green monkey) cells.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate, Porcine

Product Type:
Antibody

Isotype:
IgM

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Western Blot

Clone:
MEM-122

Conjugate:
Unconjugated

Gene:
CD47

Gene Alias:
9130415E20Rik; AA407862; AI848868; antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; AW108519; B430305P08Rik; Cd47; CD47 antigen; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 antigen/integrin-associated protein; CD47 glycoprotein; CD47 molecule; CD47/IAP; IAP; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; Itgp; Leukocyte surface antigen CD47; MER6; OA3; Protein MER6; Rh-related antigen; sCD47; soluble CD 47; soluble CD47

Host Species:
Mouse

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
397042, 961

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-675-891

--


Antigen:
CD48

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P09326

Gene Symbols:
Cd48

Immunogen:
Burkitt's lymphoma cell line Raji.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
MEM-102

Conjugate:
Unconjugated

Gene:
Cd48

Gene Alias:
AI449234; AW610730; B-cell activation marker; BCM1; Bcm-1; BCM1 surface antigen; BLAST; BLAST1; BLAST-1; B-lymphocyte activation marker BLAST-1; Cd48; CD48 antigen; CD48 antigen (B cell membrane protein); CD48 antigen (B-cell membrane protein); Cd48 molecule; CD48d; hCD48; HM48-1; leukocyte antigen MEM-102; mCD48; MEM-102; MRC OX-45 surface antigen; sCD 48; sCD48; Sgp-60; Signaling lymphocytic activation molecule 2; Signaling lymphocytic activation molecule 2 (SLAMF2); SLAM family member 2; SLAMF2; soluble CD 48; soluble CD48; TCT.1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
962

Content And Storage:
4° C, do not freeze

Form:
Liquid