01-676-231
CD45 Monoclonal Antibody (MEM-28), Biotin, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-676-231-Each-of-1 | In Stock | ₹ 43,250.58 |
01-676-231 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,250.58
GST (18%): ₹ 7,785.104
Total Price: ₹ 51,035.684
Antigen
CD45
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
P08575
Gene Symbols
PTPRC
Immunogen
Human thymocytes and T lymphocytes.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
MEM-28
Conjugate
Biotin
Gene
PTPRC
Gene Alias
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220
Host Species
Mouse
Purification Method
Size-exclusion chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5788
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- This antibody reacts with all alternative forms of human CD45 antigen, and will not cross-react with equine
- Western blotting: non-reducing conditions; 6-7% gel recommended (band around 180-250 kDa)
- CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes
- CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues
- CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
- CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains
- CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
- CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
- CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling
- CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.
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Antigen: CD45
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: P08575
Gene Symbols: PTPRC
Immunogen: Human thymocytes and T lymphocytes.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: MEM-28
Conjugate: Biotin
Gene: PTPRC
Gene Alias: B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220
Host Species: Mouse
Purification Method: Size-exclusion chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5788
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD45
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P08575
Gene Symbols:
PTPRC
Immunogen:
Human thymocytes and T lymphocytes.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
MEM-28
Conjugate:
Biotin
Gene:
PTPRC
Gene Alias:
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220
Host Species:
Mouse
Purification Method:
Size-exclusion chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5788
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: CD45RA
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 15mM sodium azide; pH 8
Gene Accession No.: P08575
Gene Symbols: PTPRC
Immunogen: Human thymocytes and T lymphocytes.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: MEM-56
Conjugate: Biotin
Gene: PTPRC
Gene Alias: B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; Leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T100; T200; T200 glycoprotein; T200 leukocyte common antigen
Host Species: Mouse
Purification Method: Size-exclusion chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5788
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD45RA
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 15mM sodium azide; pH 8
Gene Accession No.:
P08575
Gene Symbols:
PTPRC
Immunogen:
Human thymocytes and T lymphocytes.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
MEM-56
Conjugate:
Biotin
Gene:
PTPRC
Gene Alias:
B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; Leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T100; T200; T200 glycoprotein; T200 leukocyte common antigen
Host Species:
Mouse
Purification Method:
Size-exclusion chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5788
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: CD48
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: P09326
Gene Symbols: Cd48
Immunogen: Burkitt's lymphoma cell line Raji.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry
Clone: MEM-102
Conjugate: Biotin
Gene: Cd48
Gene Alias: AI449234; AW610730; B-cell activation marker; BCM1; Bcm-1; BCM1 surface antigen; BLAST; BLAST1; BLAST-1; B-lymphocyte activation marker BLAST-1; Cd48; CD48 antigen; CD48 antigen (B cell membrane protein); CD48 antigen (B-cell membrane protein); Cd48 molecule; CD48d; hCD48; HM48-1; leukocyte antigen MEM-102; mCD48; MEM-102; MRC OX-45 surface antigen; sCD 48; sCD48; Sgp-60; Signaling lymphocytic activation molecule 2; Signaling lymphocytic activation molecule 2 (SLAMF2); SLAM family member 2; SLAMF2; soluble CD 48; soluble CD48; TCT.1
Host Species: Mouse
Purification Method: Size-exclusion chromatography
Regulatory Status: RUO
Gene ID (Entrez): 962
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD48
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P09326
Gene Symbols:
Cd48
Immunogen:
Burkitt's lymphoma cell line Raji.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
MEM-102
Conjugate:
Biotin
Gene:
Cd48
Gene Alias:
AI449234; AW610730; B-cell activation marker; BCM1; Bcm-1; BCM1 surface antigen; BLAST; BLAST1; BLAST-1; B-lymphocyte activation marker BLAST-1; Cd48; CD48 antigen; CD48 antigen (B cell membrane protein); CD48 antigen (B-cell membrane protein); Cd48 molecule; CD48d; hCD48; HM48-1; leukocyte antigen MEM-102; mCD48; MEM-102; MRC OX-45 surface antigen; sCD 48; sCD48; Sgp-60; Signaling lymphocytic activation molecule 2; Signaling lymphocytic activation molecule 2 (SLAMF2); SLAM family member 2; SLAMF2; soluble CD 48; soluble CD48; TCT.1
Host Species:
Mouse
Purification Method:
Size-exclusion chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
962
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: CD55
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: TBS with 15mM sodium azide; pH 8
Gene Accession No.: P08174
Gene Symbols: CD55
Immunogen: T cell line HPB-ALL.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgM
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: MEM-118
Conjugate: Biotin
Gene: CD55
Gene Alias: CD55; CD55 antigen; CD55 molecule (Cromer blood group); CD55 molecule, decay accelerating factor for complement; CD55 molecule, decay accelerating factor for complement (Cromer blood group); Cd55a; Complement decay-accelerating factor; complement decay-accelerating factor, GPI-anchored; complement-glycosylphosphatidylinositol; CR; CROM; Cromer blood group; Daf; Daf1; DAF-GPI; decay accelarating factor 1; decay accelerating factor 1; decay accelerating factor GPI-form; decay-accelarating factor; glycosylphophatidylinositol-anchored form; GPI anchor addition signal; GPI-DAF; RP11-357P18.1; TC
Host Species: Mouse
Purification Method: Size-exclusion chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1604
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD55
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
TBS with 15mM sodium azide; pH 8
Gene Accession No.:
P08174
Gene Symbols:
CD55
Immunogen:
T cell line HPB-ALL.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgM
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
MEM-118
Conjugate:
Biotin
Gene:
CD55
Gene Alias:
CD55; CD55 antigen; CD55 molecule (Cromer blood group); CD55 molecule, decay accelerating factor for complement; CD55 molecule, decay accelerating factor for complement (Cromer blood group); Cd55a; Complement decay-accelerating factor; complement decay-accelerating factor, GPI-anchored; complement-glycosylphosphatidylinositol; CR; CROM; Cromer blood group; Daf; Daf1; DAF-GPI; decay accelarating factor 1; decay accelerating factor 1; decay accelerating factor GPI-form; decay-accelarating factor; glycosylphophatidylinositol-anchored form; GPI anchor addition signal; GPI-DAF; RP11-357P18.1; TC
Host Species:
Mouse
Purification Method:
Size-exclusion chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1604
Content And Storage:
4° C, do not freeze
Form:
Liquid