01-675-889

CD47 Monoclonal Antibody (MEM-122), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 01-675-889-Each-of-1 In Stock ₹ 36,961.92

01-675-889 - Each of 1

₹ 36,961.92

In Stock

Quantity

1

Base Price: ₹ 36,961.92

GST (18%): ₹ 6,653.146

Total Price: ₹ 43,615.066

Antigen

CD47

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 15mM sodium azide; pH 8

Gene Accession No.

Q08722, Q9GKE8

Gene Symbols

CD47

Immunogen

COS-7 (African green monkey) cells.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Non-human Primate, Porcine

Product Type

Antibody

Isotype

IgM

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Western Blot

Clone

MEM-122

Conjugate

Unconjugated

Gene

CD47

Gene Alias

9130415E20Rik; AA407862; AI848868; antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; AW108519; B430305P08Rik; Cd47; CD47 antigen; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 antigen/integrin-associated protein; CD47 glycoprotein; CD47 molecule; CD47/IAP; IAP; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; Itgp; Leukocyte surface antigen CD47; MER6; OA3; Protein MER6; Rh-related antigen; sCD47; soluble CD 47; soluble CD47

Host Species

Mouse

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

397042, 961

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • This antibody is purified from ascites by CHT-chromatagraphy and precipitation methods
  • CD47 (integrin-associated protein, IAP) is a ubiquitously expressed cell surface transmembrane glycoprotein interacting with several integrins and regulating their functions
  • Engagement of CD47 by soluble ligands or counter receptors modulates various signaling pathways, such as activation of heterotrimeric G proteins
  • Functionally, CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix
  • CD47 is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction
  • CD47 has broad tissue distribution, is reduced in expression on Rh erythrocytes
  • CD47 acts as a ligand for CD172a (signal regulatory protein alpha, SIRP alpha), an immune inhibitory receptor on macrophages; this interaction prevents phagocytosis of CD47-positive cells
  • Moreover, CD47-CD172a system affects cell migration, B cell adhesion, T cell activation, and is involved in modulation of chondrocyte responses to mechanical signals, and promotes neuronal development, being especially abundant in synapse-rich regions of brain and retina.

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Img

Thermo Scientific

01-675-889

--


Antigen:
CD47

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 15mM sodium azide; pH 8

Gene Accession No.:
Q08722, Q9GKE8

Gene Symbols:
CD47

Immunogen:
COS-7 (African green monkey) cells.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate, Porcine

Product Type:
Antibody

Isotype:
IgM

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Western Blot

Clone:
MEM-122

Conjugate:
Unconjugated

Gene:
CD47

Gene Alias:
9130415E20Rik; AA407862; AI848868; antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; AW108519; B430305P08Rik; Cd47; CD47 antigen; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 antigen/integrin-associated protein; CD47 glycoprotein; CD47 molecule; CD47/IAP; IAP; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; Itgp; Leukocyte surface antigen CD47; MER6; OA3; Protein MER6; Rh-related antigen; sCD47; soluble CD 47; soluble CD47

Host Species:
Mouse

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
397042, 961

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-675-891

--


Antigen:
CD48

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P09326

Gene Symbols:
Cd48

Immunogen:
Burkitt's lymphoma cell line Raji.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
MEM-102

Conjugate:
Unconjugated

Gene:
Cd48

Gene Alias:
AI449234; AW610730; B-cell activation marker; BCM1; Bcm-1; BCM1 surface antigen; BLAST; BLAST1; BLAST-1; B-lymphocyte activation marker BLAST-1; Cd48; CD48 antigen; CD48 antigen (B cell membrane protein); CD48 antigen (B-cell membrane protein); Cd48 molecule; CD48d; hCD48; HM48-1; leukocyte antigen MEM-102; mCD48; MEM-102; MRC OX-45 surface antigen; sCD 48; sCD48; Sgp-60; Signaling lymphocytic activation molecule 2; Signaling lymphocytic activation molecule 2 (SLAMF2); SLAM family member 2; SLAMF2; soluble CD 48; soluble CD48; TCT.1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
962

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-675-895

--


Antigen:
ICAM-1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P05362, Q00238, Q95132

Gene Symbols:
ICAM1

Immunogen:
Burkitt's lymphoma cell line Raji.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
MEM-111

Conjugate:
Unconjugated

Gene:
ICAM1

Gene Alias:
BB2; CD54; cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly 47; Ly-47; major group rhinovirus receptor; MALA2; MALA-2; MyD10; P3.58; sCD54; soluble CD54; Surface antigen of activated B cells

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
25464, 281839, 3383

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

01-675-899

--


Antigen:
CD55

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 15mM sodium azide; pH 8

Gene Accession No.:
P08174

Gene Symbols:
CD55

Immunogen:
T cell line HPB-ALL.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgM

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
MEM-118

Conjugate:
Unconjugated

Gene:
CD55

Gene Alias:
CD55; CD55 antigen; CD55 molecule (Cromer blood group); CD55 molecule, decay accelerating factor for complement; CD55 molecule, decay accelerating factor for complement (Cromer blood group); Cd55a; Complement decay-accelerating factor; complement decay-accelerating factor, GPI-anchored; complement-glycosylphosphatidylinositol; CR; CROM; Cromer blood group; Daf; Daf1; DAF-GPI; decay accelarating factor 1; decay accelerating factor 1; decay accelerating factor GPI-form; decay-accelarating factor; glycosylphophatidylinositol-anchored form; GPI anchor addition signal; GPI-DAF; RP11-357P18.1; TC

Host Species:
Mouse

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1604

Content And Storage:
4° C, do not freeze

Form:
Liquid