01-676-037
CD63 Monoclonal Antibody (MEM-259), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-676-037-Each-of-1 | In Stock | ₹ 51,079.32 |
01-676-037 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,079.32
GST (18%): ₹ 9,194.278
Total Price: ₹ 60,273.598
Antigen
CD63
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
P08962
Gene Symbols
CD63
Immunogen
T cell line HPB-ALL.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone
MEM-259
Conjugate
Unconjugated
Gene
CD63
Gene Alias
C75951; CD 63; Cd63; CD63 antigen; CD63 antigen (melanoma 1 antigen); Cd63 molecule; CD63 protein; granulophysin; LAMP-3; Lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; mast cell antigen AD1; ME491; melanoma 1 antigen; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; Ocular melanoma-associated antigen; OMA81H; Tetraspanin-30; TSPAN30; tspan-30
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
967
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- Clone MEM-259 reacts with an extracellular/luminal epitope of CD63 (LAMP-3), a 40-60 kDa tetraspan glycoprotein expressed by granulocytes, platelets, T cells, monocytes/macrophages and endothelial cells
- Cell surface exposition of CD63 is usually activation-dependent
- CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types
- CD63 is also present in the plasma membrane, usually following cell activation
- Hence, CD63 has become a widely used basophil activation marker
- In mast cells, however, CD63 exposition does not need their activation
- CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels
- CD63 also serves as a T-cell costimulation molecule
- Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas
- CD63 is expressed on activated platelets, and is a lysosomal membrane glycoprotein that is translocated to plasma membrane after platelet activation
- CD63 is also present in monocytes and macrophages and is weakly expressed on granulocytes, B, and T cells
- CD63 is identical to the melanoma-associated antigen which is ME491 and to the platelet antigen PTLGP40
- Diseases associated with CD63 dysfunction include melanoma and Hermansky-Pudlak Syndrome.
Compare Similar Items
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Antigen: CD63
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: P08962
Gene Symbols: CD63
Immunogen: T cell line HPB-ALL.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone: MEM-259
Conjugate: Unconjugated
Gene: CD63
Gene Alias: C75951; CD 63; Cd63; CD63 antigen; CD63 antigen (melanoma 1 antigen); Cd63 molecule; CD63 protein; granulophysin; LAMP-3; Lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; mast cell antigen AD1; ME491; melanoma 1 antigen; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; Ocular melanoma-associated antigen; OMA81H; Tetraspanin-30; TSPAN30; tspan-30
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 967
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD63
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P08962
Gene Symbols:
CD63
Immunogen:
T cell line HPB-ALL.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
MEM-259
Conjugate:
Unconjugated
Gene:
CD63
Gene Alias:
C75951; CD 63; Cd63; CD63 antigen; CD63 antigen (melanoma 1 antigen); Cd63 molecule; CD63 protein; granulophysin; LAMP-3; Lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; mast cell antigen AD1; ME491; melanoma 1 antigen; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; Ocular melanoma-associated antigen; OMA81H; Tetraspanin-30; TSPAN30; tspan-30
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
967
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: TRIM
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: Q6PIZ9
Gene Symbols: TRAT1
Immunogen: Recombinant intracellular domain (aa 29-186) of human TRIM.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry, Immunoprecipitation, Western Blot
Clone: TRIM-04
Conjugate: Unconjugated
Gene: TRAT1
Gene Alias: C030046M14Rik; HSPC062; pp29/30; T cell receptor associated transmembrane adaptor 1; T cell receptor interacting molecule; T-cell receptor interacting molecule; T-cell receptor-associated transmembrane adapter 1; T-cell receptor-interacting molecule; TCRIM; Trat1; TRIM
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 50852
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
TRIM
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
Q6PIZ9
Gene Symbols:
TRAT1
Immunogen:
Recombinant intracellular domain (aa 29-186) of human TRIM.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Immunoprecipitation, Western Blot
Clone:
TRIM-04
Conjugate:
Unconjugated
Gene:
TRAT1
Gene Alias:
C030046M14Rik; HSPC062; pp29/30; T cell receptor associated transmembrane adaptor 1; T cell receptor interacting molecule; T-cell receptor interacting molecule; T-cell receptor-associated transmembrane adapter 1; T-cell receptor-interacting molecule; TCRIM; Trat1; TRIM
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
50852
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: SIT
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: Q9Y3P8
Gene Symbols: SIT1
Immunogen: Bacterially produced, recombinant, intracellular fragment of human SIT.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunoprecipitation, Western Blot
Clone: SIT-01
Conjugate: Unconjugated
Gene: SIT1
Gene Alias: gp30/40; MGC125908; MGC125909; MGC125910; RP11-331F9.5; SHP2 interacting transmembrane adaptor; SHP-2 interacting transmembrane adaptor protein; SHP2-interacting transmembrane adapter protein; SHP2-interacting transmembrane adaptor protein; signaling threshold regulating transmembrane adaptor 1; signaling threshold-regulating transmembrane adapter 1; SIT; SIT1; SIT-R; suppression inducing transmembrane adaptor 1; suppression-inducing transmembrane adapter 1
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 27240
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
SIT
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
Q9Y3P8
Gene Symbols:
SIT1
Immunogen:
Bacterially produced, recombinant, intracellular fragment of human SIT.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunoprecipitation, Western Blot
Clone:
SIT-01
Conjugate:
Unconjugated
Gene:
SIT1
Gene Alias:
gp30/40; MGC125908; MGC125909; MGC125910; RP11-331F9.5; SHP2 interacting transmembrane adaptor; SHP-2 interacting transmembrane adaptor protein; SHP2-interacting transmembrane adapter protein; SHP2-interacting transmembrane adaptor protein; signaling threshold regulating transmembrane adaptor 1; signaling threshold-regulating transmembrane adapter 1; SIT; SIT1; SIT-R; suppression inducing transmembrane adaptor 1; suppression-inducing transmembrane adapter 1
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
27240
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: PAG1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: Q9NWQ8
Gene Symbols: PAG1
Immunogen: Recombinant intracellular fragment (aa 97-432) of human Cbp (PAG).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone: MEM-255
Conjugate: Unconjugated
Gene: PAG1
Gene Alias: CBP; Csk binding protein; csk-binding protein; F730007C19Rik; Pag; PAG 1; Pag1; PAG1B; phosphoprotein associated with glycosphingolipid microdomains 1; phosphoprotein associated with glycosphingolipid-enriched microdomains 1; phosphoprotein membrane anchor with glycosphingolipid microdomains 1; phosphoprotein transmembrane adaptor 1; phosphoprotein-associated with GEMs; pregnancy-associated glycoprotein 1; Pregnancy-specific protein B; PSP-B; similar to pregnancy-associated glycoprotein 1; transmembrane adapter protein PAG; transmembrane adaptor protein PAG; transmembrane phosphoprotein Cbp
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 55824
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
PAG1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
Q9NWQ8
Gene Symbols:
PAG1
Immunogen:
Recombinant intracellular fragment (aa 97-432) of human Cbp (PAG).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone:
MEM-255
Conjugate:
Unconjugated
Gene:
PAG1
Gene Alias:
CBP; Csk binding protein; csk-binding protein; F730007C19Rik; Pag; PAG 1; Pag1; PAG1B; phosphoprotein associated with glycosphingolipid microdomains 1; phosphoprotein associated with glycosphingolipid-enriched microdomains 1; phosphoprotein membrane anchor with glycosphingolipid microdomains 1; phosphoprotein transmembrane adaptor 1; phosphoprotein-associated with GEMs; pregnancy-associated glycoprotein 1; Pregnancy-specific protein B; PSP-B; similar to pregnancy-associated glycoprotein 1; transmembrane adapter protein PAG; transmembrane adaptor protein PAG; transmembrane phosphoprotein Cbp
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
55824
Content And Storage:
4° C, do not freeze
Form:
Liquid