01-675-961
LCK Monoclonal Antibody (LCK-01), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-675-961-Each-of-1 | In Stock | ₹ 42,822.78 |
01-675-961 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,822.78
GST (18%): ₹ 7,708.10
Total Price: ₹ 50,530.88
Antigen
LCK
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
P06239
Gene Symbols
LCK
Immunogen
Peptide corresponding to amino acids 22-36 in the sequence of human Lck.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
LCK-01
Conjugate
Unconjugated
Gene
LCK
Gene Alias
EC 2.7.10.2; Hck-3; IMD22; kinase Lck; Lck; LCK proto-oncogene, Src family tyrosine kinase; Lck1; Lcktkr; leukocyte C-terminal Src kinase; LSK; Lskt; Lsk-t; Lymphocyte cell-specific protein-tyrosine kinase; lymphocyte protein tyrosine kinase; lymphocyte-specific protein tyrosine kinase; OTTHUMP00000008640; OTTHUMP00000008740; OTTHUMP00000008741; p56(LSTRA) protein-tyrosine kinase; p56<lck>; p56lck; p56-LCK; pp58lck; Protein YT16; Proto-oncogene Lck; Proto-oncogene tyrosine-protein kinase LCK; RP4-675E8.4; t cell-specific protein-tyrosine kinase; T-lymphocyte specific protein tyrosine kinase p56lck; tyr; tyrosine-protein kinase Lck; YT16
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3932
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- This antibody will not cross-react with mouse
- LCK is a member of the Src-family tyrosine kinase, which are essential for signaling through the T-cell receptor (TCR) complex
- Upon TCR triggering, LCK phosphorylates the ITAM motives in its zeta subunits establishing binding sites for the SH2 domains of the tyrosine kinase ZAP70, which is also phosphorylated by LCK and activated to generate subsequent signaling platforms by phosphorylation of adaptor LAT
- The majority of LCK is localized to the plasma membrane, however, there is also a significant fraction associated with the Golgi apparatus which may contribute to Raf activation under conditions of weak stimulation through the TCR
- LCK contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively
- LCK is also involved in the regulation of apoptosis induced by various stimuli, but not by the death receptors
- Diseases associated with LCK include Immunodeficiency 22 and CD45 deficiency
- Alternatively splice variants of the LCK gene encoding different isoforms of the protein have been found.
Compare Similar Items
Show Difference
Antigen: LCK
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: P06239
Gene Symbols: LCK
Immunogen: Peptide corresponding to amino acids 22-36 in the sequence of human Lck.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: LCK-01
Conjugate: Unconjugated
Gene: LCK
Gene Alias: EC 2.7.10.2; Hck-3; IMD22; kinase Lck; Lck; LCK proto-oncogene, Src family tyrosine kinase; Lck1; Lcktkr; leukocyte C-terminal Src kinase; LSK; Lskt; Lsk-t; Lymphocyte cell-specific protein-tyrosine kinase; lymphocyte protein tyrosine kinase; lymphocyte-specific protein tyrosine kinase; OTTHUMP00000008640; OTTHUMP00000008740; OTTHUMP00000008741; p56(LSTRA) protein-tyrosine kinase; p56<lck>; p56lck; p56-LCK; pp58lck; Protein YT16; Proto-oncogene Lck; Proto-oncogene tyrosine-protein kinase LCK; RP4-675E8.4; t cell-specific protein-tyrosine kinase; T-lymphocyte specific protein tyrosine kinase p56lck; tyr; tyrosine-protein kinase Lck; YT16
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3932
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
LCK
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P06239
Gene Symbols:
LCK
Immunogen:
Peptide corresponding to amino acids 22-36 in the sequence of human Lck.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
LCK-01
Conjugate:
Unconjugated
Gene:
LCK
Gene Alias:
EC 2.7.10.2; Hck-3; IMD22; kinase Lck; Lck; LCK proto-oncogene, Src family tyrosine kinase; Lck1; Lcktkr; leukocyte C-terminal Src kinase; LSK; Lskt; Lsk-t; Lymphocyte cell-specific protein-tyrosine kinase; lymphocyte protein tyrosine kinase; lymphocyte-specific protein tyrosine kinase; OTTHUMP00000008640; OTTHUMP00000008740; OTTHUMP00000008741; p56(LSTRA) protein-tyrosine kinase; p56<lck>; p56lck; p56-LCK; pp58lck; Protein YT16; Proto-oncogene Lck; Proto-oncogene tyrosine-protein kinase LCK; RP4-675E8.4; t cell-specific protein-tyrosine kinase; T-lymphocyte specific protein tyrosine kinase p56lck; tyr; tyrosine-protein kinase Lck; YT16
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3932
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: CD31
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: P16284
Gene Symbols: Pecam1
Immunogen: Leucocytes from a patient suffering from a LGL type leukaemia.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: MEM-05
Conjugate: Unconjugated
Gene: Pecam1
Gene Alias: C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5175
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD31
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P16284
Gene Symbols:
Pecam1
Immunogen:
Leucocytes from a patient suffering from a LGL type leukaemia.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
MEM-05
Conjugate:
Unconjugated
Gene:
Pecam1
Gene Alias:
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5175
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: CD147 (soluble)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: P35613
Gene Symbols: BSG
Immunogen: Protein A-CR purified soluble recombinant form of CD147.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: MEM-M6/1
Conjugate: Unconjugated
Gene: BSG
Gene Alias: 5A11; 5A11 antigen; 5A11/Basigin; 5A11/Basigin-2; 5F7; AI115436; AI325119; Basic immunoglobulin superfamily; basigin; basigin (Ok blood group); Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); basignin; Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); blood-brain barrier HT7 antigen; BSG; CD147; CD147 antigen; CE9; Collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; glycoprotein CE9; gp 42; gp42/basigin/OX-47/HT7; HT7; HT-7; HT7 antigen; immunoglobulin gene superfamily member; leukocyte activation antigen M6; Membrane glycoprotein gp42; neurothelin; OK; OK blood group antigen; OX-47 antigen; Ox47R; RPE7; TCSF; tumor cell-derived collagenase stimulatory factor; Unknown (protein for MGC:128392); unnamed protein product; UNQ6505/PRO21383
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 682
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD147 (soluble)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P35613
Gene Symbols:
BSG
Immunogen:
Protein A-CR purified soluble recombinant form of CD147.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
MEM-M6/1
Conjugate:
Unconjugated
Gene:
BSG
Gene Alias:
5A11; 5A11 antigen; 5A11/Basigin; 5A11/Basigin-2; 5F7; AI115436; AI325119; Basic immunoglobulin superfamily; basigin; basigin (Ok blood group); Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); basignin; Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); blood-brain barrier HT7 antigen; BSG; CD147; CD147 antigen; CE9; Collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; glycoprotein CE9; gp 42; gp42/basigin/OX-47/HT7; HT7; HT-7; HT7 antigen; immunoglobulin gene superfamily member; leukocyte activation antigen M6; Membrane glycoprotein gp42; neurothelin; OK; OK blood group antigen; OX-47 antigen; Ox47R; RPE7; TCSF; tumor cell-derived collagenase stimulatory factor; Unknown (protein for MGC:128392); unnamed protein product; UNQ6505/PRO21383
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
682
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: SEMA7A
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 15mM sodium azide; pH 8
Gene Accession No.: O75326
Gene Symbols: SEMA7A
Immunogen: T cell line HPB-ALL.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgM
Applications: Flow Cytometry, Immunoprecipitation, Western Blot
Clone: MEM-150
Conjugate: Unconjugated
Gene: SEMA7A
Gene Alias: 2900057C09Rik; CD108; CDw108; H-Sema K1; H-SEMA-K1; H-Sema-L; JMH; JMH blood group antigen; John Milton Hagen blood group H-Sema K1; john-Milton-Hargen human blood group Ag; MGC126692; MGC126696; M-Sema-L; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group); sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A; sema K1; Sema L; SEMA7A; SEMAK1; SEMAL; semaphorin 7A (John Milton Hagen blood group); semaphorin 7A, GPI membrane anchor; semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group); Semaphorin K1; semaphorin-7A; Semaphorin-K1; semaphorin-L; Semk1
Host Species: Mouse
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8482
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
SEMA7A
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 15mM sodium azide; pH 8
Gene Accession No.:
O75326
Gene Symbols:
SEMA7A
Immunogen:
T cell line HPB-ALL.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgM
Applications:
Flow Cytometry, Immunoprecipitation, Western Blot
Clone:
MEM-150
Conjugate:
Unconjugated
Gene:
SEMA7A
Gene Alias:
2900057C09Rik; CD108; CDw108; H-Sema K1; H-SEMA-K1; H-Sema-L; JMH; JMH blood group antigen; John Milton Hagen blood group H-Sema K1; john-Milton-Hargen human blood group Ag; MGC126692; MGC126696; M-Sema-L; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group); sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A; sema K1; Sema L; SEMA7A; SEMAK1; SEMAL; semaphorin 7A (John Milton Hagen blood group); semaphorin 7A, GPI membrane anchor; semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group); Semaphorin K1; semaphorin-7A; Semaphorin-K1; semaphorin-L; Semk1
Host Species:
Mouse
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8482
Content And Storage:
4° C, do not freeze
Form:
Liquid