01-676-430

TRF2 Monoclonal Antibody (4A794.15), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 01-676-430-Each-of-1 In Stock ₹ 51,250.44

01-676-430 - Each of 1

₹ 51,250.44

In Stock

Quantity

1

Base Price: ₹ 51,250.44

GST (18%): ₹ 9,225.079

Total Price: ₹ 60,475.519

Antigen

TRF2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

O35144, Q15554

Gene Symbols

TERF2

Immunogen

Full-length TRF2 protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Deer, Human, Marsupial, Mouse, Rat

Product Type

Antibody

Isotype

IgG1 κ

Applications

ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Proximity Ligation Assay, Western Blot

Clone

4A794.15

Conjugate

Unconjugated

Gene

TERF2

Gene Alias

Telomeric DNA-binding protein; telomeric repeat binding factor 2; telomeric repeat binding protein 2; telomeric repeat-binding factor 2; TERF2; TRBF2; TRF2; TTAGGG repeat-binding factor 2

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

21750, 361403, 7014

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • The TRF2 antibody is referred to as both clone 4A794.15 and 4A794 in the published literature
  • This antibody recognizes full-length TRF2 as well as TRF2 forms lacking both the N-terminal basic domain (B) and the telobox Myb-like C-terminal DNA-binding domain (M)
  • TRF2 forms missing the B and M domains are often referred to as mutant TRF2.Although the exact epitope recognized by the TRF2 antibody has not been mapped, the scientific literature indicates it is in the D or L domain, but not in the B or M domain
  • Suggested positive control: HL-60, antigen standard for TERF2 (transient overexpression lysate)
  • TRF2 is a ubiquitously expressed protein that is implicated in the control of telomere length
  • TRF2, like TRF1 contains a Myb-related DNA binding motif
  • It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes
  • TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini
  • The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells
  • Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types.

Compare Similar Items

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Img

Thermo Scientific

01-676-430

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Antigen:
TRF2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O35144, Q15554

Gene Symbols:
TERF2

Immunogen:
Full-length TRF2 protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Deer, Human, Marsupial, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Proximity Ligation Assay, Western Blot

Clone:
4A794.15

Conjugate:
Unconjugated

Gene:
TERF2

Gene Alias:
Telomeric DNA-binding protein; telomeric repeat binding factor 2; telomeric repeat binding protein 2; telomeric repeat-binding factor 2; TERF2; TRBF2; TRF2; TTAGGG repeat-binding factor 2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
21750, 361403, 7014

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-432

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Antigen:
RAD9

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q99638

Gene Symbols:
RAD9A

Immunogen:
Fusion protein of human full length Rad9.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
93A535

Conjugate:
Unconjugated

Gene:
RAD9A

Gene Alias:
Cell cycle checkpoint control protein RAD9A; chromatin-binding protein RAD9; DNA repair exonuclease rad9 homolog A; DNA repair protein RAD9; hRAD9; mRAD9; QtsA-19913; Rad9; RAD9 checkpoint clamp component A; RAD9 homolog A; RAD9 homolog A (S. pombe); Rad9a; Rad9-like protein; rCG47324-like; unnamed protein product; YD9934.02C; YDR217C

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5883

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-438

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Antigen:
PARP1 (cleaved Asp214, Asp215)

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P09874, P11103

Gene Symbols:
PARP1

Immunogen:
Synthetic peptide corresponding to residues near the 214/215-cleavage site of human PARP.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
194C1439

Conjugate:
Unconjugated

Gene:
PARP1

Gene Alias:
5830444G22Rik; ADP-ribosyltransferase (NAD+; ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase 1; ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); Adprp; Adprt; ADPRT 1; ADPRT1; AI893648; ARTD1; C80510; DNA ADP-ribosyltransferase PARP1; msPARP; NAD(+) ADP-ribosyltransferase 1; pADPRT-1; PARP; Parp1; PARP-1; poly (ADP-ribose) polymerase 1; poly (ADP-ribose) polymerase family, member 1; poly (ADP-ribose) polymerase); poly [ADP-ribose] polymerase 1; poly(ADP-ribose) polymerase; poly(ADP-ribose) polymerase 1; poly(ADP-ribose) polymerase PARP-1; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; poly[ADP-ribose] synthase 1; poly[ADP-ribose] synthetase 1; PPOL; Protein poly-ADP-ribosyltransferase PARP1; sPARP-1; synthetase fragment (AA 67); Unknown (protein for IMAGE:8023736); unnamed protein product

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11545, 142

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-442

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Antigen:
TRAIL

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P50591

Gene Symbols:
TNFSF10

Immunogen:
Synthetic peptide corresponding to residues 17-35 of human TRAIL.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
55B709.3

Conjugate:
Unconjugated

Gene:
TNFSF10

Gene Alias:
A330042I21Rik; AI448571; Apo-2 ligand; APO2L; Apo-2L; CD253; CD253 antigen; chemokine tumor necrosis factor ligand superfamily member 10; Ly81; Protein TRAIL; TL2; TN; TNF superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis inducing ligand TRAIL; TNF-related apoptosis-inducing ligand; Tnfsf10; TNLG6A; TRAIL; TRAIL protein; TRAIL/APO2L; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor (ligand) superfamily member 10; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor ligand 6A; tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
8743

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid