01-676-442

TRAIL Monoclonal Antibody (55B709.3), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 01-676-442-Each-of-1 In Stock ₹ 45,731.82

01-676-442 - Each of 1

₹ 45,731.82

In Stock

Quantity

1

Base Price: ₹ 45,731.82

GST (18%): ₹ 8,231.728

Total Price: ₹ 53,963.548

Antigen

TRAIL

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

P50591

Gene Symbols

TNFSF10

Immunogen

Synthetic peptide corresponding to residues 17-35 of human TRAIL.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

55B709.3

Conjugate

Unconjugated

Gene

TNFSF10

Gene Alias

A330042I21Rik; AI448571; Apo-2 ligand; APO2L; Apo-2L; CD253; CD253 antigen; chemokine tumor necrosis factor ligand superfamily member 10; Ly81; Protein TRAIL; TL2; TN; TNF superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis inducing ligand TRAIL; TNF-related apoptosis-inducing ligand; Tnfsf10; TNLG6A; TRAIL; TRAIL protein; TRAIL/APO2L; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor (ligand) superfamily member 10; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor ligand 6A; tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

8743

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • This peptide sequence has been shown to be involved in TRaIL and DR5 (TRaIL-R2) interaction
  • Suggested positive control: Jurkat whole cell lysate
  • TRAIL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family
  • TRAIL preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues
  • TRAIL binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG
  • The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis
  • The binding of TRAIL protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3
  • Receptors for TRAIL include two death domain containing receptors, death receptor 4 (DR4) and DR5, as well as two decoy receptors, DcR1 and DcR2, lacking the intracellular signaling death domain
  • TRAIL is a type II membrane protein and expressed in a variety of human tissues
  • Like TNF and Fas ligand, TRAIL induces apoptosis and NF-kB activation in many tissues and cells.

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Img

Thermo Scientific

01-676-442

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Antigen:
TRAIL

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P50591

Gene Symbols:
TNFSF10

Immunogen:
Synthetic peptide corresponding to residues 17-35 of human TRAIL.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
55B709.3

Conjugate:
Unconjugated

Gene:
TNFSF10

Gene Alias:
A330042I21Rik; AI448571; Apo-2 ligand; APO2L; Apo-2L; CD253; CD253 antigen; chemokine tumor necrosis factor ligand superfamily member 10; Ly81; Protein TRAIL; TL2; TN; TNF superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis inducing ligand TRAIL; TNF-related apoptosis-inducing ligand; Tnfsf10; TNLG6A; TRAIL; TRAIL protein; TRAIL/APO2L; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor (ligand) superfamily member 10; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor ligand 6A; tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
8743

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-443

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Antigen:
TRAF2

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q12933

Gene Symbols:
TRAF2

Immunogen:
Fusion protein corresponding to residues 205-222 of human TRAF2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
33A1293

Conjugate:
Unconjugated

Gene:
TRAF2

Gene Alias:
AI325259; E3 ubiquitin-protein ligase TRAF2; MGC:45012; OTTHUMP00000064745; RING-type E3 ubiquitin transferase TRAF2; TNF receptor associated factor 2; Tnf receptor-associated factor 2; TRAF2; TRAP; TRAP3; tumor necrosis factor type 2 receptor associated protein 3; tumor necrosis factor type 2 receptor-associated protein 3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
7186

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-449

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Antigen:
HTRA2

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
O43464

Gene Symbols:
HTRA2

Immunogen:
Synthetic peptide corresponding to residues 335-350 of human Htra2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
196C429

Conjugate:
Unconjugated

Gene:
HTRA2

Gene Alias:
AI481710; High temperature requirement protein A2; HtrA serine peptidase 2; HtrA2; HtrA-like serine protease; mnd2; motor neuron degeneration 2; OMI; Omi stress-regulated endoprotease; PARK13; protease, serine, 25; Prss25; Serine protease 25; serine protease HTRA2, mitochondrial; serine protease OMI; serine proteinase OMI

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
27429

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-452

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Antigen:
PGRP-S

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O75594, O88593

Gene Symbols:
PGLYRP1

Immunogen:
Synthetic peptide, KLH-conjugated, corresponding to residues 165-180 of human PGRP-S.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG3 κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
188C424

Conjugate:
Unconjugated

Gene:
PGLYRP1

Gene Alias:
Cytokine tag7; MGC126894; MGC126896; peptidoglycan recognition protein 1; Peptidoglycan recognition protein short; Pglyrp; Pglyrp1; PGRP; PGRPS; PGRP-S; SBBI68; Tag7; Tasg7; TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein); TNFSF3L; UNQ639/PRO1269

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
21946, 8993

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid