01-676-449

HTRA2 Monoclonal Antibody (196C429), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 01-676-449-Each-of-1 In Stock ₹ 45,646.26

01-676-449 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

HTRA2

Classification

Monoclonal

Conjugate

Unconjugated

Gene

HTRA2

Gene Alias

AI481710; High temperature requirement protein A2; HtrA serine peptidase 2; HtrA2; HtrA-like serine protease; mnd2; motor neuron degeneration 2; OMI; Omi stress-regulated endoprotease; PARK13; protease, serine, 25; Prss25; Serine protease 25; serine protease HTRA2, mitochondrial; serine protease OMI; serine proteinase OMI

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

27429

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

196C429

Formulation

PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.

O43464

Gene Symbols

HTRA2

Immunogen

Synthetic peptide corresponding to residues 335-350 of human Htra2.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Suggested positive control: HL-60 or Jurkat whole cell lysate
  • The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli
  • All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity (1-3)
  • Recently, a serine protease has been isolated, which is released from the mitochondria upon induction of apoptosis by apoptotic stimuli
  • This protein called Omi/HtrA2 is a mitochondrial protein that binds to IAP (4)
  • Like Smac/DIABLO, the mature Omi protein contains a conserved IAP-binding motif (AVPS) at its N terminus
  • The deregulated expression of Omi in the cytoplasm of mammalian cells induces apoptosis indicating that Omi could participate in the mitochondrial apoptotic pathway.

Compare Similar Items

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Img

Thermo Scientific

01-676-449

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Antigen:
HTRA2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
HTRA2

Gene Alias:
AI481710; High temperature requirement protein A2; HtrA serine peptidase 2; HtrA2; HtrA-like serine protease; mnd2; motor neuron degeneration 2; OMI; Omi stress-regulated endoprotease; PARK13; protease, serine, 25; Prss25; Serine protease 25; serine protease HTRA2, mitochondrial; serine protease OMI; serine proteinase OMI

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
27429

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
196C429

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
O43464

Gene Symbols:
HTRA2

Immunogen:
Synthetic peptide corresponding to residues 335-350 of human Htra2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Thermo Scientific

01-676-452

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Antigen:
PGRP-S

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PGLYRP1

Gene Alias:
Cytokine tag7; MGC126894; MGC126896; peptidoglycan recognition protein 1; Peptidoglycan recognition protein short; Pglyrp; Pglyrp1; PGRP; PGRPS; PGRP-S; SBBI68; Tag7; Tasg7; TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein); TNFSF3L; UNQ639/PRO1269

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
21946, 8993

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
188C424

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O75594, O88593

Gene Symbols:
PGLYRP1

Immunogen:
Synthetic peptide, KLH-conjugated, corresponding to residues 165-180 of human PGRP-S.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG3 κ

Img

Thermo Scientific

01-676-454

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Antigen:
RANK

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TNFRSF11A

Gene Alias:
CD265; FEO; LOH18CR1; loss of heterozygosity, 18, chromosomal region 1; Ly109; mRANK; ODFR; OFE; OPTB7; Osteoclast differentiation factor receptor; OSTS; Paget disease of bone 2; PDB2; Rank; receptor activator of NF-kappaB; receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; RGD1563614; TNF receptor superfamily member 11a; Tnfrsf11a; TRANCER; TRANCE-R; tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
21934, 8792

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
64C1385.1

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O35305, Q9Y6Q6

Gene Symbols:
TNFRSF11A

Immunogen:
Recombinant protein corresponding to the extracellular domain (aa 33-208) of human RANK.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 λ

Img

Thermo Scientific

01-676-455

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Antigen:
DR4

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TNFRSF10A

Gene Alias:
APO2; CD261; cytotoxic TRAIL receptor; death receptor 4; DR4; MGC9365; sCD261; soluble CD261; soluble TRAIL; sTRAIL; TNF receptor superfamily member 10a; TNF-related apoptosis-inducing ligand receptor 1; TNFRSF10A; TRAIL R1; TRAIL receptor 1; TRAILR1; TRAIL-R1; TRAILR-1; tumor necrosis factor receptor superfamily member 10A; tumor necrosis factor receptor superfamily member 10a variant 2; tumor necrosis factor receptor superfamily, member 10a

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
8797

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
32A242

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O00220

Gene Symbols:
TNFRSF10A

Immunogen:
Synthetic peptide corresponding to residues 2-21 of mature human DR4.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1