01-676-477

CD254 (RANK Ligand) Monoclonal Antibody (12A668), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 01-676-477-Each-of-1 In Stock ₹ 48,298.62

01-676-477 - Each of 1

₹ 48,298.62

In Stock

Quantity

1

Base Price: ₹ 48,298.62

GST (18%): ₹ 8,693.752

Total Price: ₹ 56,992.372

Antigen

CD254 (RANK Ligand)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

O14788, O35235, Q9ESE2

Gene Symbols

TNFSF11

Immunogen

Bacterially expressed fusion protein corresponding to residues 1-317 of mouse RANK-L.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1 κ

Applications

ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

12A668

Conjugate

Unconjugated

Gene

TNFSF11

Gene Alias

CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

117516, 21943, 8600

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • Suggested positive control: activated T cells or RAW, antigen standard for TNFSF11 (transient overexpression lysate)
  • This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation
  • This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response
  • T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss
  • This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis
  • Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts
  • The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy
  • Two alternatively spliced transcript variants have been found.

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Thermo Scientific

01-676-477

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Antigen:
CD254 (RANK Ligand)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O14788, O35235, Q9ESE2

Gene Symbols:
TNFSF11

Immunogen:
Bacterially expressed fusion protein corresponding to residues 1-317 of mouse RANK-L.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
12A668

Conjugate:
Unconjugated

Gene:
TNFSF11

Gene Alias:
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
117516, 21943, 8600

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-479

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Antigen:
pro-Caspase 3

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P42574

Gene Symbols:
CASP3

Immunogen:
Recombinant full-length human Caspase-3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
31A893

Conjugate:
Unconjugated

Gene:
CASP3

Gene Alias:
A830040C14Rik; AC-3; Apopain; Casp3; CASP-3; caspase 3; caspase 3, apoptosis related cysteine protease; caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; CC3; Cpp32; CPP-32; CPP32B; cysteine protease CPP32; LICE; mLdy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
836

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-482

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Antigen:
SARS Coronavirus Spike Protein

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Synthetic peptide corresponding to residues 1124-1140 of human SARS-Spike protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Virus

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
17F706R

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

01-676-483

--


Antigen:
Factor VIII

Classification:
Monoclonal

Concentration:
8.1 mg/mL

Formulation:
50% water with 50% glycerol and no preservative

Gene Accession No.:
Q06194

Gene Symbols:
F8

Immunogen:
Mouse Factor VIII.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
__

Applications:
ELISA, Western Blot

Clone:
9035

Conjugate:
Unconjugated

Gene:
F8

Gene Alias:
AHF; Antihemophilic factor; CF8; Cf-8; coagulation factor VIII; coagulation factor VIII A1 domain; coagulation factor VIII C2 domain; coagulation factor VIII, procoagulant component; coagulation factor VIII, procoagulant component (hemophilia A); coagulation factor VIIIc; DXS1253E; F8; F8B; F8C; Factor 8; Factor VIII; Factor VIII B chain; factor VIII F8B; factor VIII precursor; Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIIIa light chain; factor8; FVIII; HEMA; Procoagulant component; RP11-115M6.7

Host Species:
Rat

Purification Method:
Ammonium sulfate precipitation, Ion-exchange chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14069

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid