01-676-752

Zap-70 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-676-752-Each-of-1 In Stock ₹ 38,844.24

01-676-752 - Each of 1

₹ 38,844.24

In Stock

Quantity

1

Base Price: ₹ 38,844.24

GST (18%): ₹ 6,991.963

Total Price: ₹ 45,836.203

Antigen

Zap-70

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ZAP70

Gene Alias

70 kDa zeta-associated protein; 70 kDa zeta-chain associated protein; ADMIO2; EC 2.7.10.2; FLJ17670; FLJ17679; I79_004087; IMD48; kinase ZAP70; mrtle; mur; Selective T cell defect; Srk; STCD; STD; syk-related protein tyrosine kinase; syk-related tyrosine kinase; Tyrosine-protein kinase ZAP-70; Tyrosine-protein kinase ZAP-70;TZK; TZK; ZA70; Zap70; ZAP-70; Zeta chain associated protein kinase 70kDa; zeta chain of T cell receptor associated protein kinase; zeta chain of T cell receptor associated protein kinase 70; zeta chain of T cell receptor associated protein kinase 70kDa; zeta-chain (TCR) associated protein kinase; zeta-chain (TCR) associated protein kinase 70; zeta-chain (TCR) associated protein kinase 70kDa; zeta-chain associated protein kinase 70kDa; zeta-chain associated protein kinase, 70kD

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7535

Content And Storage

4° C, do not freeze

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

P43403

Gene Symbols

ZAP70

Immunogen

Bacterially expressed fusion protein representing C-terminal part (160 amino acids) of human ZAP-70 with histidine tag

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Novus Biologicals

NB251132

--

Img

Thermo Scientific

01-676-751

--

Img

Thermo Scientific

PIMA544822

--

Img

Thermo Scientific

PIPA520405

--

Img

Thermo Scientific

PIPA582401

--

Img

Thermo Scientific

PIPA551650

--

Img

Thermo Scientific

PIPA572832

--

Img

Novus Biologicals

N272149J549

--

Description

  • This antibody recognizes the C-terminal part of human ZAP-70 protein tyrosine kinase
  • ZAP-70 is a molecule susceptible to degradation
  • It is recommended to use freshly prepared cell lysates (protease inhibitors are essential) to avoid non-specific staining of degradation products Western Blot: Reducing conditions
  • ZAP-70 is a cytosolic protein tyrosine kinase that is a member of the Syk family of proteins
  • ZAP-70 is expressed exclusively in T-cells and natural killer cells and is required for T-cell receptor activation
  • Upon T cell antigen receptor (TCR) engagement, ZAP70 is phosphorylated on tyrosines 292, 315 and 319 in the interdomain B, located between the SH2 and kinase domains
  • Phosphorylation of both tyrosines 315 (a Vav binding site) and 319 (a Lck binding site) enhances ZAP70 function in mediating lymphocyte signaling, while tyrosine 292 terminates the transient activation of ZAP70 and attentuates lymphocyte signaling.

Compare Similar Items

Show Difference

Img

Thermo Scientific

01-676-752

--


Antigen:
Zap-70

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZAP70

Gene Alias:
70 kDa zeta-associated protein; 70 kDa zeta-chain associated protein; ADMIO2; EC 2.7.10.2; FLJ17670; FLJ17679; I79_004087; IMD48; kinase ZAP70; mrtle; mur; Selective T cell defect; Srk; STCD; STD; syk-related protein tyrosine kinase; syk-related tyrosine kinase; Tyrosine-protein kinase ZAP-70; Tyrosine-protein kinase ZAP-70;TZK; TZK; ZA70; Zap70; ZAP-70; Zeta chain associated protein kinase 70kDa; zeta chain of T cell receptor associated protein kinase; zeta chain of T cell receptor associated protein kinase 70; zeta chain of T cell receptor associated protein kinase 70kDa; zeta-chain (TCR) associated protein kinase; zeta-chain (TCR) associated protein kinase 70; zeta-chain (TCR) associated protein kinase 70kDa; zeta-chain associated protein kinase 70kDa; zeta-chain associated protein kinase, 70kD

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7535

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P43403

Gene Symbols:
ZAP70

Immunogen:
Bacterially expressed fusion protein representing C-terminal part (160 amino acids) of human ZAP-70 with histidine tag

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-676-753

--


Antigen:
Kinesin 5B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KIF5B

Gene Alias:
AL022807; Conventional kinesin heavy chain; EMBL:ABC25059.1}; epididymis secretory protein Li 61; HEL-S-61; Khc; Khcs; KIF5A; KIF5B; kif5b {ECO:0000312; kinesin 1 (110-120kD); kinesin family member 5A; kinesin family member 5B; kinesin heavy chain; kinesin heavy chain member 5B, ubiquitous; kinesin-1 heavy chain; KINH; KNS; Kns1; ubiquitous kinesin heavy chain; UKHC; U-KHC; Unknown (protein for IMAGE:7944745)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16573, 3799, 595132

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P33176, Q61768

Gene Symbols:
KIF5B

Immunogen:
Stalk domain of human kinesin, expressed in (aa 331-906) E. coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Porcine

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-676-757

--


Antigen:
NTAL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LAT2

Gene Alias:
AW125574; HSPC046; LAB; Lat2; LAT-2 like; Linker for activation of B-cells; linker for activation of T cells family, member 2; linker for activation of T cells, transmembrane adaptor 2; linker for activation of T-cells family member 2; Membrane-associated adapter molecule; non-T cell activation linker; non-T-cell activation linker; NTAL; WBS15; WBSCR15; WBSCR5; Williams-Beuren syndrome chromosomal region 15 protein; williams-Beuren syndrome chromosomal region 15 protein homolog; Williams-Beuren syndrome chromosomal region 5 protein; Williams-Beuren syndrome chromosome region 5 homolog; Williams-Beuren syndrome chromosome region 5-like protein; WSCR5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56743

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
Q9JHL0

Gene Symbols:
LAT2

Immunogen:
Recombinant N-terminal cytoplasmic domain (aa 124-203) of mouse NTAL.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-676-759

--


Antigen:
Neisseria meningitidis Orf1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Meningococcus

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Slices containing purified FrpD250-6xHis-tagged protein were excised from 10% SDS-PAGE gels, grinded, mixed with 1 mg/ml of aluminum hydroxide in PBS.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bacteria

Product Type:
Antibody

Isotype:
IgG