01-950-177

VEGF Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-950-177-Each-of-1 In Stock ₹ 47,443.02

01-950-177 - Each of 1

₹ 47,443.02

In Stock

Quantity

1

Base Price: ₹ 47,443.02

GST (18%): ₹ 8,539.744

Total Price: ₹ 55,982.764

Antigen

VEGF

Classification

Polyclonal

Conjugate

Unconjugated

Gene

VEGFA

Gene Alias

angiogenic factor; etID309976.16; eVEGF120; eVEGF164; human VEGF121 homolog; MGC70609; MVCD1; ovine vascular endothelial growth factor; RP1-261G23.1; unnamed protein product; VAS; vascular endothelial growth factor; vascular endothelial growth factor (VEGF) precursor; vascular endothelial growth factor 121 isoform; vascular endothelial growth factor 164; vascular endothelial growth factor 165b; vascular endothelial growth factor 182; vascular endothelial growth factor 182 isoform; vascular endothelial growth factor 188; vascular endothelial growth factor 188 isoform; vascular endothelial growth factor 189; vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular endothelial growth factor Aa; Vascular endothelial growth factor A-A; vascular endothelial growth factor isoform 165; vascular permeability factor; Vasculotropin; VEGF; VEGF1; VEGF164; VEGF182; VEGF188; vegfa; VEGF-A; VEGFA165b; vegfaa; VEGF-A-A; VEGFMGC70609; VPF; VPF ant; wu:fj82c06

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100033839, 100713483, 22339, 281572, 395909, 403802, 7422, 83785

Content And Storage

4° C, do not freeze

Form

Liquid

Applications

ELISA, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P15691, P15692, P16612, P26617, P67964, Q00731, Q9GKR0, Q9MYV3

Gene Symbols

VEGFA

Immunogen

Synthetic peptide between residues 180-232 of human VEGFA protein sequence.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Bovine, Canine, Chicken, Equine, Guinea Pig, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • In Western blot, a band is seen at ∽42 kDa with a chimera transfected lysate representing the homodimer VEGFA
  • Another faint band is seen at ∽21 kDa, representing the monodomer form of VEGFA
  • This antibody is not recommended for IHC applications.Suggested positive control: antigen standard for VEGFA (transient overexpression lysate)
  • VEGF (vascular endothelial growth factor) which is a 45 kDa homodimeric, disulfide-linked glycoprotein involved in angiogenesis which promotes tumor progression and metastasis
  • VEGF has a variety of effects on vascular endothelium, including the ability to promote endothelial cell viability, mitogenesis, chemotaxis, and vascular permeability
  • The VEGF family currently includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF
  • VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis
  • Most tumors have the absolute requirement of angiogenesis, and VEGF has been described as the most potent angiogenic cytokine linked to this process
  • To date 5 different isoforms of VEGF have been described
  • These isoforms are generated as the result of alternative splicing from a single VEGF gene
  • These various isoforms have been shown to bind to two tyrosine-kinase receptors flt-1 (VEGFR-1) and flk-1/KDR (VEGFR-2), which have been found to be expressed almost exclusively on endothelial cells
  • VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature
  • Studies have shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity, playing an inhibitory role in angiogenesis
  • Elevated levels of VEGF is linked to POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy, Skin changes) also known as Crow-Fukase syndrome which affects multiple organs in the body.

Compare Similar Items

Show Difference

Img

Thermo Scientific

01-950-177

--


Antigen:
VEGF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
VEGFA

Gene Alias:
angiogenic factor; etID309976.16; eVEGF120; eVEGF164; human VEGF121 homolog; MGC70609; MVCD1; ovine vascular endothelial growth factor; RP1-261G23.1; unnamed protein product; VAS; vascular endothelial growth factor; vascular endothelial growth factor (VEGF) precursor; vascular endothelial growth factor 121 isoform; vascular endothelial growth factor 164; vascular endothelial growth factor 165b; vascular endothelial growth factor 182; vascular endothelial growth factor 182 isoform; vascular endothelial growth factor 188; vascular endothelial growth factor 188 isoform; vascular endothelial growth factor 189; vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular endothelial growth factor Aa; Vascular endothelial growth factor A-A; vascular endothelial growth factor isoform 165; vascular permeability factor; Vasculotropin; VEGF; VEGF1; VEGF164; VEGF182; VEGF188; vegfa; VEGF-A; VEGFA165b; vegfaa; VEGF-A-A; VEGFMGC70609; VPF; VPF ant; wu:fj82c06

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100033839, 100713483, 22339, 281572, 395909, 403802, 7422, 83785

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P15691, P15692, P16612, P26617, P67964, Q00731, Q9GKR0, Q9MYV3

Gene Symbols:
VEGFA

Immunogen:
Synthetic peptide between residues 180-232 of human VEGFA protein sequence.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Chicken, Equine, Guinea Pig, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-950-179

--


Antigen:
CRYAB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cryab

Gene Alias:
2310001E10Rik; 3526402H21Rik; AACRYA; active transcription factor CREB; alpha B-crystallin; alpha crystallin B; alpha(B)-crystallin; alpha-B-crystallin; Alpha-crystallin B chain; alpha-crystallin B chain-like protein; AV083133; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; CMD1II; CREB; CREB1; CREB-1; Crya2; Crya-2; CRYAB; CryAB antibody; crystallin alpha B; crystallin, alpha 2; crystallin, alpha B; crystallin, alpha polypeptide 2; CTPP2; CTRCT16; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; cyclic AMP-responsive element-binding protein 1; epididymis secretory protein Li 101; heat shock protein beta-5; heat shock protein CryAB; heat shock protein HspB5; heat-shock 20 kD like-protein; HEL-S-101; HSPB5; HspB5 protein; MFM2; P23; Renal carcinoma antigen NY-REN-27; rosenthal fiber component; transactivator protein; Y protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12955, 1410, 25420

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.08 mg/mL

Formulation:
phosphate, tris citrate with 0.1% sodium azide; pH 7-8

Gene Accession No.:
P02511, P23927, P23928

Gene Symbols:
Cryab

Immunogen:
Synthetic peptide between amino acids 70-140 of the human Crystallin AB protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-950-182

--


Antigen:
LOX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LOX

Gene Alias:
AI893619; cross-linking enzyme; H-rev142; LOX; Lysyl oxidase; Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts); MGC105112; protein-lysine 6-oxidase; Protein-lysine 6-oxidase, long form; Protein-lysine 6-oxidase, short form; Ras excision protein; ras recision; rrg; Rrg1; TSC-160

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100525278, 16948, 24914, 4015

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P16636, P28300, P28301, P45845

Gene Symbols:
LOX

Immunogen:
Synthetic peptide between amino acids 200-300 of the human LOX protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-950-184

--


Antigen:
LOX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LOX

Gene Alias:
AI893619; cross-linking enzyme; H-rev142; LOX; Lysyl oxidase; Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts); MGC105112; protein-lysine 6-oxidase; Protein-lysine 6-oxidase, long form; Protein-lysine 6-oxidase, short form; Ras excision protein; ras recision; rrg; Rrg1; TSC-160

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100525278, 16948, 24914, 280841, 4015

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P16636, P28300, P28301, P33072, P45845

Gene Symbols:
LOX

Immunogen:
Cocktail of two synthetic peptides between amino acids 300-350 and amino acids 200-300 of the human LOX protein.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG