06-255-IMI
MilliporeSigma™ anti-JAK2, Polyclonal
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 06-255-IMI-Each-of-1 | In Stock | ₹ 37,706.63 |
06-255-IMI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,706.63
GST (18%): ₹ 6,787.193
Total Price: ₹ 44,493.823
Antigen
JAK2
Classification
Polyclonal
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
Jak2
Immunogen
KLH-conjugated linear peptide corresponding to residues 758-776 of mouse JAK2.
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_001041642
Content And Storage
2°C to 8°C for one year
Applications
Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Gene Accession No.
Q62120
Host Species
Rabbit
Purification Method
Protein A purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Purified
Related Products
Description
- Specifically detects JAK2 Clone: in Human, Mouse, Rat samples, and it is validated for Immunoprecipitation, Western Blotting Tyrosine-protein kinase JAK2 (EC 2.7.10.2; UniProt Q62120; also known as JAK-2, Janus kinase 2) is encoded by the Jak2 (also known as Fd17) gene (Gene ID 16452) in murine species
- JAK2 belongs to the family of non-receptor Janus tyrosine kinases that regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system
- Immunological stimuli, such as interferons and cytokines cause the recruitment of Stat transcription factors to cytokine receptor
- Subsequent phosphorylation by receptor-associated JAK2 causes Stat dimerization, nuclear translocation, and Stat-mediated target genes transcription
- The canonical JAK/Stat pathway is integral to maintaining a normal immune system by stimulating proliferation, differentiation, survival, and host resistance to pathogens
- Altering JAK/Stat signaling to reduce immune cells cytokine responses represents an attractive target for anti-inflammatory therapies
- Within the JAK2 kinase domain, there is a region that has considerable sequence homology to the regulatory region of the insulin receptor.
Compare Similar Items
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Antigen: JAK2
Classification: Polyclonal
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Jak2
Immunogen: KLH-conjugated linear peptide corresponding to residues 758-776 of mouse JAK2.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_001041642
Content And Storage: 2°C to 8°C for one year
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene Accession No.: Q62120
Host Species: Rabbit
Purification Method: Protein A purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Purified
Antigen:
JAK2
Classification:
Polyclonal
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Jak2
Immunogen:
KLH-conjugated linear peptide corresponding to residues 758-776 of mouse JAK2.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001041642
Content And Storage:
2°C to 8°C for one year
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene Accession No.:
Q62120
Host Species:
Rabbit
Purification Method:
Protein A purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Purified
Antigen: Giα3
Classification: Polyclonal
Formulation: Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105M NaCl, 0.035% sodium azide as a preservative.
Gene Symbols: GNAI3; 87U6; G; FLJ26559; ialpha-3).
Immunogen: peptide corresponding to the C-terminal region of Giα3 (KNNLKECGLY)
Quantity: 50 μL
Research Discipline: __
Gene ID (Entrez): NM_006496
Content And Storage: −20°C in undiluted aliquotes for 24 months. Avoid repeated freeze/thaw cycles.
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Hamster, Human, Mouse, Rat
Form: Serum
Antigen:
Giα3
Classification:
Polyclonal
Formulation:
Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105M NaCl, 0.035% sodium azide as a preservative.
Gene Symbols:
GNAI3; 87U6; G; FLJ26559; ialpha-3).
Immunogen:
peptide corresponding to the C-terminal region of Giα3 (KNNLKECGLY)
Quantity:
50 μL
Research Discipline:
__
Gene ID (Entrez):
NM_006496
Content And Storage:
−20°C in undiluted aliquotes for 24 months. Avoid repeated freeze/thaw cycles.
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Hamster, Human, Mouse, Rat
Form:
Serum
Antigen: JAK1
Classification: Polyclonal
Formulation: whole rabbit antiserum containing 0.05% sodium azide
Gene Symbols: JAK1; JAK1B; JAK1A; JAK-1
Immunogen: HPLC-purified (≥98%) peptide corresponding to 21 amino acids of human JAK1 (KTLIEKERFYESRCRPVTPS-C)
Quantity: 150 μL
Research Discipline: __
Gene ID (Entrez): NM_002227
Content And Storage: −20°C for 24 months
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Antiserum
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Hamster, Human, Mouse, Rabbit, Rat
Form: Serum
Antigen:
JAK1
Classification:
Polyclonal
Formulation:
whole rabbit antiserum containing 0.05% sodium azide
Gene Symbols:
JAK1; JAK1B; JAK1A; JAK-1
Immunogen:
HPLC-purified (≥98%) peptide corresponding to 21 amino acids of human JAK1 (KTLIEKERFYESRCRPVTPS-C)
Quantity:
150 μL
Research Discipline:
__
Gene ID (Entrez):
NM_002227
Content And Storage:
−20°C for 24 months
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Antiserum
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Hamster, Human, Mouse, Rabbit, Rat
Form:
Serum
Antigen: Nitrotyrosine
Classification: Monoclonal
Formulation: Purified rabbit antibody conjugate in PBS with 15 mg/ml BSA and 0.1% sodium azide.
Gene Symbols: __
Immunogen: Nitrated KLH.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): __
Content And Storage: 2°C to 8°C for one year from date of shipment
Applications: Immunocytochemistry
Conjugate: Alexa Fluor 488
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Nitrotyrosine
Classification:
Monoclonal
Formulation:
Purified rabbit antibody conjugate in PBS with 15 mg/ml BSA and 0.1% sodium azide.
Gene Symbols:
__
Immunogen:
Nitrated KLH.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
__
Content And Storage:
2°C to 8°C for one year from date of shipment
Applications:
Immunocytochemistry
Conjugate:
Alexa Fluor 488
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified