06-284-AF488

MilliporeSigma™ anti-Nitrotyrosine Rabbit Monoclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 06-284-AF488-Each-of-1 In Stock ₹ 53,733.39

06-284-AF488 - Each of 1

₹ 53,733.39

In Stock

Quantity

1

Base Price: ₹ 53,733.39

GST (18%): ₹ 9,672.01

Total Price: ₹ 63,405.40

Antigen

Nitrotyrosine

Classification

Monoclonal

Formulation

Purified rabbit antibody conjugate in PBS with 15 mg/ml BSA and 0.1% sodium azide.

Immunogen

Nitrated KLH.

Quantity

100 μL

Research Discipline

Signaling

Test Specificity

Recognizes proteins which are nitrated.

Content And Storage

2°C to 8°C for one year from date of shipment

Isotype

IgG

Applications

Immunocytochemistry

Conjugate

Alexa Fluor 488

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

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Description

  • Specifically detects Nitrotyrosine Clone: in Human samples, and it is validated for Immunocytochemistry Nitrotyrosine is a product of tyrosine nitration mediated by reactive nitrogen species
  • Proteins are often targets of reactive species and detection of oxidatively modified proteins is often used as an index of oxidative stress
  • Peroxynitrite is a strong oxidant formed by reaction of nitric oxide with superoxide
  • The reaction of proteins with peroxynitrite results in the oxidation of tryptophan and cysteine, as well as the nitration of tyrosine, formation of dityrosine, 2,4 dinitrophenylhydrazine-reactive carbonyls, and protein fragmentation
  • The formation of 3-nitrotyrosine represents a specific peroxynitrite-mediated protein modification that is different from modifications mediated by reactive oxygen species
  • Studies show that elevated nitrotyrosine levels are associated with inflammatory conditions, such as atherosclerotic plaques and rheumatoid arthritis.

Compare Similar Items

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Img

MilliporeSigma™

06-284-AF488

--


Antigen:
Nitrotyrosine

Classification:
Monoclonal

Formulation:
Purified rabbit antibody conjugate in PBS with 15 mg/ml BSA and 0.1% sodium azide.

Immunogen:
Nitrated KLH.

Quantity:
100 μL

Research Discipline:
Signaling

Test Specificity:
Recognizes proteins which are nitrated.

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgG

Applications:
Immunocytochemistry

Conjugate:
Alexa Fluor 488

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma™

06-284-AF647

--


Antigen:
Nitrotyrosine

Classification:
Polyclonal

Formulation:
Purified rabbit antibody conjugate in PBS with 15mg/mL BSA and 0.1% sodium azide.

Immunogen:
Nitratred KLH.

Quantity:
100 μL

Research Discipline:
Signaling

Test Specificity:
Recognizes proteins which are nitrated.

Content And Storage:
2°C to 8°C for one year

Isotype:
__

Applications:
Immunohistochemistry

Conjugate:
Alexa Fluor 647

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma

06-284-MI

--


Antigen:
Nitrotyrosine

Classification:
Polyclonal

Formulation:
Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105M NaCl, 0.035% sodium azide as a preservative.

Immunogen:
Nitrated KLH

Quantity:
100 μg

Research Discipline:
__

Test Specificity:
__

Content And Storage:
−20°C in undiluted aliquotes for 12 months. Avoid repeated freeze/thaw cycles.

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Purification Method:
Immunoaffinity purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
All species

Form:
Purified

Img

MilliporeSigma

06-288-MI

--


Antigen:
Nck

Classification:
Polyclonal

Formulation:
0.1M Tris-glycine, pH 7.4, 0.15M NaCl containing 0.05% sodium azide

Immunogen:
Purified GST fusion protein produced in E. coli., corresponding to human Nck amino acid sequence 1 to 254

Quantity:
100 μg

Research Discipline:
__

Test Specificity:
__

Content And Storage:
−20°C for 24 months

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Purification Method:
Protein G chromatography

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Purified