06-284-AF647

MilliporeSigma™ anti-Nitrotyrosine, Alexa Fluor 647, Polyclonal

Manufacturer: MilliporeSigma™

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Pack Size SKU Availability Price
Each of 1 06-284-AF647-Each-of-1 In Stock ₹ 53,733.39

06-284-AF647 - Each of 1

₹ 53,733.39

In Stock

Quantity

1

Base Price: ₹ 53,733.39

GST (18%): ₹ 9,672.01

Total Price: ₹ 63,405.40

Antigen

Nitrotyrosine

Classification

Polyclonal

Formulation

Purified rabbit antibody conjugate in PBS with 15mg/mL BSA and 0.1% sodium azide.

Immunogen

Nitratred KLH.

Quantity

100 μL

Research Discipline

Signaling

Test Specificity

Recognizes proteins which are nitrated.

Content And Storage

2°C to 8°C for one year

Applications

Immunohistochemistry

Conjugate

Alexa Fluor 647

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

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Description

  • Specifically detects Nitrotyrosine Clone: in Human samples, and it is validated for Immunohistochemistry Nitrotyrosine is a product of tyrosine nitration mediated by reactive nitrogen species
  • Proteins are often targets of reactive species and detection of oxidatively modified proteins is often used as an index of oxidative stress
  • Peroxynitrite is a strong oxidant formed by reaction of nitric oxide with superoxide
  • The reaction of proteins with peroxynitrite results in the oxidation of tryptophan and cysteine, as well as the nitration of tyrosine, formation of dityrosine, 2,4 dinitrophenylhydrazine-reactive carbonyls, and protein fragmentation
  • The formation of 3-nitrotyrosine represents a specific peroxynitrite-mediated protein modification that is different from modifications mediated by reactive oxygen species
  • Studies show that elevated nitrotyrosine levels are associated with inflammatory conditions, such as atherosclerotic plaques and rheumatoid arthritis.

Compare Similar Items

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Img

MilliporeSigma™

06-284-AF647

--


Antigen:
Nitrotyrosine

Classification:
Polyclonal

Formulation:
Purified rabbit antibody conjugate in PBS with 15mg/mL BSA and 0.1% sodium azide.

Immunogen:
Nitratred KLH.

Quantity:
100 μL

Research Discipline:
Signaling

Test Specificity:
Recognizes proteins which are nitrated.

Content And Storage:
2°C to 8°C for one year

Applications:
Immunohistochemistry

Conjugate:
Alexa Fluor 647

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma

06-284-MI

--


Antigen:
Nitrotyrosine

Classification:
Polyclonal

Formulation:
Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105M NaCl, 0.035% sodium azide as a preservative.

Immunogen:
Nitrated KLH

Quantity:
100 μg

Research Discipline:
__

Test Specificity:
__

Content And Storage:
−20°C in undiluted aliquotes for 12 months. Avoid repeated freeze/thaw cycles.

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Purification Method:
Immunoaffinity purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
All species

Form:
Purified

Img

MilliporeSigma

06-288-MI

--


Antigen:
Nck

Classification:
Polyclonal

Formulation:
0.1M Tris-glycine, pH 7.4, 0.15M NaCl containing 0.05% sodium azide

Immunogen:
Purified GST fusion protein produced in E. coli., corresponding to human Nck amino acid sequence 1 to 254

Quantity:
100 μg

Research Discipline:
__

Test Specificity:
__

Content And Storage:
−20°C for 24 months

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Purification Method:
Protein G chromatography

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Purified

Img

MilliporeSigma

06-315-MI

--


Antigen:
KA2/GRIK5 (Kainate Receptor)

Classification:
Polyclonal

Formulation:
of 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%

Immunogen:
21 residue synthetic peptide (KTSPPRPRPGPTGPRELTEHE) corresponding to the c-terminus of rat KA2 with a lysine added to the n-terminus

Quantity:
200 μg

Research Discipline:
__

Test Specificity:
__

Content And Storage:
−20°C for 24 months

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Purification Method:
Protein G chromatography

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Rabbit, Rat

Form:
Purified