11-181-942
CD181 (CXCR1) Monoclonal Antibody (eBio8F1-1-4 (8F1-1-4)), FITC, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 11-181-942-Each-of-1 | In Stock | ₹ 23,614.56 |
11-181-942 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,614.56
GST (18%): ₹ 4,250.621
Total Price: ₹ 27,865.181
Antigen
CD181 (CXCR1)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P25024
Gene Symbols
CXCR1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3577
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
eBio8F1-1-4 (8F1-1-4)
Conjugate
FITC
Gene
CXCR1
Gene Alias
C Cmotif chemokine; C X C motif chemokine; C-C; CC motif chemokine; C-C-CKR-1; CCmotif chemokine; CD128; CD181; CDw128a; chemokine (C-X-C motif) receptor 1; CKR-1; CMKAR1; CXC; CXC chemokine receptor 1; C-X-C chemokine receptor type 1; CXC motif chemokine; C-X-C motif chemokine receptor 1; CXCR1; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 receptor; IL-8 Receptor alpha; IL-8 Receptor IL-RA; IL-8 receptor type 1; IL-8R A; IL8R1; Il8ra; IL8RBA; IL-RA; interleukin 8 receptor; interleukin 8 receptor alpha; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b κ
Related Products
Description
- Description: The eBio8F1-1-4 monoclonal antibody reacts with human CD181 (CXCR1, IL-8Ralpha)
- CD181 is a 67-70 kDa member of the 7-transmembrane spanning G-protein coupled receptor (GPCR) family
- CD181 is expressed as a homodimer, or a heterodimer with CD182 (CXCR2, IL-8Rbeta) and is expressed on granulocytes, NK cells, a subset of T cells, mast cells, monocytes, endothelial cells, megakaryocytes and oligodendrocytes
- Binding of it's ligands, which include IL-8, NAP-2, GCP-2 and GRO-alpha, induces several biological outcomes such as cell activation, chemotaxis, proliferation and angiogenesis
- There are several functional differences between CD181 and CD182
- Both receptors are able to mediate chemotaxis and intracellular calcium changes, but only CD181 mediates phospolipase D activation and respiratory burst
- Furthermore, studies have shown that IL-8 predomitly mediates its effects on neutrophil function through CD181
- Applications Reported: This eBio8F1-1-4 (8F1-1-4) antibody has been reported for use in flow cytometric analysis
- Applications Tested: This eBio8F1-1-4 (8F1-1-4) antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood
- This can be used at 5 μL (0.5 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- CXCR1 is a member of the G-protein-coupled receptor family
- This protein is a receptor for interleukin 8 (IL8)
- It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system
- Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord
- This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
Compare Similar Items
Show Difference
Antigen: CD181 (CXCR1)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P25024
Gene Symbols: CXCR1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3577
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: eBio8F1-1-4 (8F1-1-4)
Conjugate: FITC
Gene: CXCR1
Gene Alias: C Cmotif chemokine; C X C motif chemokine; C-C; CC motif chemokine; C-C-CKR-1; CCmotif chemokine; CD128; CD181; CDw128a; chemokine (C-X-C motif) receptor 1; CKR-1; CMKAR1; CXC; CXC chemokine receptor 1; C-X-C chemokine receptor type 1; CXC motif chemokine; C-X-C motif chemokine receptor 1; CXCR1; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 receptor; IL-8 Receptor alpha; IL-8 Receptor IL-RA; IL-8 receptor type 1; IL-8R A; IL8R1; Il8ra; IL8RBA; IL-RA; interleukin 8 receptor; interleukin 8 receptor alpha; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD181 (CXCR1)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P25024
Gene Symbols:
CXCR1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3577
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
eBio8F1-1-4 (8F1-1-4)
Conjugate:
FITC
Gene:
CXCR1
Gene Alias:
C Cmotif chemokine; C X C motif chemokine; C-C; CC motif chemokine; C-C-CKR-1; CCmotif chemokine; CD128; CD181; CDw128a; chemokine (C-X-C motif) receptor 1; CKR-1; CMKAR1; CXC; CXC chemokine receptor 1; C-X-C chemokine receptor type 1; CXC motif chemokine; C-X-C motif chemokine receptor 1; CXCR1; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 receptor; IL-8 Receptor alpha; IL-8 Receptor IL-RA; IL-8 receptor type 1; IL-8R A; IL8R1; Il8ra; IL8RBA; IL-RA; interleukin 8 receptor; interleukin 8 receptor alpha; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: CD183 (CXCR3)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O88410
Gene Symbols: CXCR3
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12766
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: CXCR3-173
Conjugate: FITC
Gene: CXCR3
Gene Alias: an; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD182; CD183; chemokine (C-X-C motif) receptor 3; chemokine receptor 3; CKR-L2; Cmkar3; CXC; C-X-C chemokine receptor type 3; CXC motif chemokine; C-X-C motif chemokine receptor 3; Cxcr3; CXC-R3; CXCR-3; G protein-coupled receptor 9; GPR9; Interferon-inducible protein 10 receptor; IP10; IP10 receptor; IP-10 receptor; IP10-R; Mig receptor; MigR; Mig-R
Host Species: Armenian Hamster
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
CD183 (CXCR3)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O88410
Gene Symbols:
CXCR3
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12766
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
CXCR3-173
Conjugate:
FITC
Gene:
CXCR3
Gene Alias:
an; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD182; CD183; chemokine (C-X-C motif) receptor 3; chemokine receptor 3; CKR-L2; Cmkar3; CXC; C-X-C chemokine receptor type 3; CXC motif chemokine; C-X-C motif chemokine receptor 3; Cxcr3; CXC-R3; CXCR-3; G protein-coupled receptor 9; GPR9; Interferon-inducible protein 10 receptor; IP10; IP10 receptor; IP-10 receptor; IP10-R; Mig receptor; MigR; Mig-R
Host Species:
Armenian Hamster
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
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