14-107-837
CD107b (LAMP-2) Monoclonal Antibody (eBioH4B4 (H4B4)), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 14-107-837-Each-of-1 | In Stock | ₹ 1,17,388.32 |
14-107-837 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,17,388.32
GST (18%): ₹ 21,129.898
Total Price: ₹ 1,38,518.218
Antigen
CD107b (LAMP-2)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P13473
Gene Symbols
LAMP2
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3920
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Western Blot
Clone
eBioH4B4 (H4B4)
Conjugate
Unconjugated
Gene
LAMP2
Gene Alias
CD107 antigen-like family member B; CD107b; EGK_20887; Igp96; Lamp II; LAMP2; LAMP-2; LAMP-2 Isoform 2A; LAMP-2 Variant A; Lamp-2a; Lamp-2b; Lamp-2c; LAMPB; LGP110; LGP-110; LGP-96; LGP-B; lysosomal associated membrane protein 2; lysosomal membrane glycoprotein 2; lysosomal membrane glycoprotein type B; lysosomal-associated membrane protein 2; lysosome-associated membrane glycoprotein 2; lysosome-associated membrane protein 2; Mac3; RP23-193O17.2
Host Species
Mouse
Quantity
2 mg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- The eBioH4B4 MAb reacts with human CD107b, also known as lysosomal-associated membrane protein-2 (LAMP-2)
- CD107b is a highly glycosylated, type I transmembrane protein of approximately 105 kDa
- It is expressed intracellularly in lysosomal/endosomal membranes in nearly all cells
- It is also expressed on the surface of degranulating T cells (to a lesser extent than CD107a) and activated platelets as well as some cancer cells
- In humans, mutations in CD107b results in a lysosomal glycogen storage disorder, known as Danon disease
- LAMP2 (Lysosome-associated membrane glycoprotein 2, CD107b) is a member of a family of membrane glycoproteins
- LAMP2 provides selectins with carbohydrate ligands, and may play a role in tumor cell metastasis, and have a function in the protection, maintenance, and adhesion of the lysosome
- Prior to posttranslational modification, LAMP2 is approximately 46 kDa polypeptide
- Mature, functional LAMP2 is extensively glycosylated with a variety of different N-linked and O-linked oligosaccharides with a total molecular weight of about 100-130 kDa
- LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail
- LAMP2 is used to monitor a very selective form of autophagy called chaperone-mediated autophagy
- LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail
- The LAMP protein has 3 variant forms: LAMP-2A, -2B, and 2C
- LAMP2, together with CD107a/LAMP-1, is a major constituent of lysosomal membrane
- The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes, and LAMP2 is an important regulator in successful phagosomal maturation
- LAMP2 deficiency causes an accumulation of autophagosomes in many tissues leading to cardiomyopathy and myopathy (Danon’s disease).
Compare Similar Items
Show Difference
Antigen: CD107b (LAMP-2)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P13473
Gene Symbols: LAMP2
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3920
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Western Blot
Clone: eBioH4B4 (H4B4)
Conjugate: Unconjugated
Gene: LAMP2
Gene Alias: CD107 antigen-like family member B; CD107b; EGK_20887; Igp96; Lamp II; LAMP2; LAMP-2; LAMP-2 Isoform 2A; LAMP-2 Variant A; Lamp-2a; Lamp-2b; Lamp-2c; LAMPB; LGP110; LGP-110; LGP-96; LGP-B; lysosomal associated membrane protein 2; lysosomal membrane glycoprotein 2; lysosomal membrane glycoprotein type B; lysosomal-associated membrane protein 2; lysosome-associated membrane glycoprotein 2; lysosome-associated membrane protein 2; Mac3; RP23-193O17.2
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD107b (LAMP-2)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P13473
Gene Symbols:
LAMP2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3920
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Western Blot
Clone:
eBioH4B4 (H4B4)
Conjugate:
Unconjugated
Gene:
LAMP2
Gene Alias:
CD107 antigen-like family member B; CD107b; EGK_20887; Igp96; Lamp II; LAMP2; LAMP-2; LAMP-2 Isoform 2A; LAMP-2 Variant A; Lamp-2a; Lamp-2b; Lamp-2c; LAMPB; LGP110; LGP-110; LGP-96; LGP-B; lysosomal associated membrane protein 2; lysosomal membrane glycoprotein 2; lysosomal membrane glycoprotein type B; lysosomal-associated membrane protein 2; lysosome-associated membrane glycoprotein 2; lysosome-associated membrane protein 2; Mac3; RP23-193O17.2
Host Species:
Mouse
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD107a (LAMP-1)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P11279
Gene Symbols: LAMP1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3916
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: eBioH4A3
Conjugate: Unconjugated
Gene: LAMP1
Gene Alias: 120 kDa lysosomal membrane glycoprotein; AI196048; CD107 antigen-like family member A; CD107a; I79_011073; Lamp I; LAMP1; LAMP-1; LAMPA; LGP120; LGP-120; LGPA; LGP-A; lysosomal associated membrane protein 1; Lysosomal associated membrane protein 1 (120 kDa); lysosomal membrane glycoprotein 1; lysosomal membrane glycoprotein A; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B); lysosome-associated membrane protein 1; P2B
Host Species: Mouse
Quantity: 10 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD107a (LAMP-1)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P11279
Gene Symbols:
LAMP1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3916
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
eBioH4A3
Conjugate:
Unconjugated
Gene:
LAMP1
Gene Alias:
120 kDa lysosomal membrane glycoprotein; AI196048; CD107 antigen-like family member A; CD107a; I79_011073; Lamp I; LAMP1; LAMP-1; LAMPA; LGP120; LGP-120; LGPA; LGP-A; lysosomal associated membrane protein 1; Lysosomal associated membrane protein 1 (120 kDa); lysosomal membrane glycoprotein 1; lysosomal membrane glycoprotein A; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B); lysosome-associated membrane protein 1; P2B
Host Species:
Mouse
Quantity:
10 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD109
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q6YHK3
Gene Symbols: CD109
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 135228
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunoprecipitation
Clone: HU17
Conjugate: Unconjugated
Gene: CD109
Gene Alias: 150 kDa TGF-beta-1-binding protein; 9930012E15Rik; activated T-cell marker CD109; AI480638; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; Cd109; CD109 antigen; CD109 molecule; CPAMD7; GARP; Gov platelet alloantigens; GPI-anchored alpha 2 macroglobulin-related protein; GPI-anchored alpha-2 macroglobulin-related protein; p180; platelet-specific Gov antigen; r150; RP11-525G3.1
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD109
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q6YHK3
Gene Symbols:
CD109
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
135228
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunoprecipitation
Clone:
HU17
Conjugate:
Unconjugated
Gene:
CD109
Gene Alias:
150 kDa TGF-beta-1-binding protein; 9930012E15Rik; activated T-cell marker CD109; AI480638; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; Cd109; CD109 antigen; CD109 molecule; CPAMD7; GARP; Gov platelet alloantigens; GPI-anchored alpha 2 macroglobulin-related protein; GPI-anchored alpha-2 macroglobulin-related protein; p180; platelet-specific Gov antigen; r150; RP11-525G3.1
Host Species:
Mouse
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD115 (c-fms)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P07333
Gene Symbols: Csf1r
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1436
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone: 12-3A3-1B10
Conjugate: Unconjugated
Gene: Csf1r
Gene Alias: AI323359; CD115; CD115 antigen; C-FMS; colony stimulating factor 1 receptor; colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog; CSF-1 receptor; CSF1R; CSF-1R; CSF-1-R; CSFIR; Csfmr; CSFR; EC 2.7.10.1; FIM2; Fim-2; FMS; fms proto-oncogene; HDLS; kinase CSFR; macrophage colony stimulating factor I receptor; macrophage colony-stimulating factor 1 receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; M-CSFR; M-CSF-R; mrfms; OTTHUMP00000224093; protein-tyrosine kinase; proto-oncogene c-Fms; proto-oncogene fms
Host Species: Rat
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD115 (c-fms)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P07333
Gene Symbols:
Csf1r
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1436
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone:
12-3A3-1B10
Conjugate:
Unconjugated
Gene:
Csf1r
Gene Alias:
AI323359; CD115; CD115 antigen; C-FMS; colony stimulating factor 1 receptor; colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog; CSF-1 receptor; CSF1R; CSF-1R; CSF-1-R; CSFIR; Csfmr; CSFR; EC 2.7.10.1; FIM2; Fim-2; FMS; fms proto-oncogene; HDLS; kinase CSFR; macrophage colony stimulating factor I receptor; macrophage colony-stimulating factor 1 receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; M-CSFR; M-CSF-R; mrfms; OTTHUMP00000224093; protein-tyrosine kinase; proto-oncogene c-Fms; proto-oncogene fms
Host Species:
Rat
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ