14-909-337
CD289 (TLR9) Monoclonal Antibody (M9.D6), eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 14-909-337-Each-of-1 | In Stock | ₹ 1,17,388.32 |
14-909-337 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,17,388.32
GST (18%): ₹ 21,129.898
Total Price: ₹ 1,38,518.218
Antigen
CD289 (TLR9)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q9EQU3
Gene Symbols
Tlr9
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
81897
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Western Blot
Clone
M9.D6
Conjugate
Unconjugated
Gene
Tlr9
Gene Alias
CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605
Host Species
Rat
Quantity
2 mg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- M9.D6 is generated against a peptide derived from the extracellular portion of mouse TLR9
- Predominantly expressed as an intracellular protein, TLR9 is a ∽115-120 kDa molecule which mediates response to unmethylated CpG dinucleotides in bacterial DNA
- CpG DNA induces a strong T-helper-1-like inflammatory response and the proliferation of TLR9+ B cells
- When stimulated with CpG DNA, TLR9-deficient (TLR9-/-) mice lacked splenocyte proliferation, inflammatory cytokine production from macrophages, and dendritic cell maturation, as compared with normal mice
- To date, at least ten members of the Toll family have been identified
- This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor
- Members of the TLR family are involved in recognition and response to different microbial components including lipoproteins, peptidoglycans, and nucleic acids and play important roles in innate immunity and inflammation
- TLR9 is not detected by flow cytometry using this antibody on RBC-lysed mouse splenocytes stained for intracellular TLR9
- This may be due to limitations of antigen detection by flow cytometry
- Further studies are needed to determine the relationship between mRNA expression and protein detection
- The protein encoded by this gene is a member of the Toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity
- TLRs are highly conserved from Drosophila to humans and share structural and functional similarities
- They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
- The various TLRs exhibit different patterns of expression
- This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes
- Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
Compare Similar Items
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Antigen: CD289 (TLR9)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9EQU3
Gene Symbols: Tlr9
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 81897
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Western Blot
Clone: M9.D6
Conjugate: Unconjugated
Gene: Tlr9
Gene Alias: CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605
Host Species: Rat
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD289 (TLR9)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9EQU3
Gene Symbols:
Tlr9
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
81897
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Western Blot
Clone:
M9.D6
Conjugate:
Unconjugated
Gene:
Tlr9
Gene Alias:
CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605
Host Species:
Rat
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD289 (TLR9)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9EQU3
Gene Symbols: Tlr9
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 81897
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Western Blot
Clone: M9.D6
Conjugate: Unconjugated
Gene: Tlr9
Gene Alias: CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605
Host Species: Rat
Quantity: 10 mg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD289 (TLR9)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9EQU3
Gene Symbols:
Tlr9
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
81897
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Western Blot
Clone:
M9.D6
Conjugate:
Unconjugated
Gene:
Tlr9
Gene Alias:
CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605
Host Species:
Rat
Quantity:
10 mg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Osteopontin
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P10451
Gene Symbols: SPP1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6696
Content And Storage: 4° C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 2F10
Conjugate: Unconjugated
Gene: SPP1
Gene Alias: 2AR; 2b7; 44 kDa bone phosphoprotein; Apl-1; BNSP; Bone sialoprotein 1; Bone sialoprotein 1 (BSPI/BSP1); Bsp; BSPI; Calcium oxalate crystal growth inhibitor protein; CALPHA1 fusion; Early T lymphocyte activation 1 (ETA1); early T-lymphocyte activation 1; early T-lymphocyte activation 1 protein; Eta; ETA-1; HGNC:11255; immunoglobulin alpha 1 heavy chain constant region fusion protein; MGC110940; Minopontin; nephropontin; Op; Opn; Opnl; OSP; osteopontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; osteopontin-like protein; PSEC0156; Ric; Secreted phosphoprotein 1; secreted phosphoprotein 1 (osteopontin bone sialoprotein I early T lymphocyte activation 1); secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); Secreted phosphoprotein 1 (SPP1); secreted phosphoprotein 1 variant 6; Sialoprotein (osteopontin); SPP1; SPP-1; SPP1/CALPHA1 fusion; unnamed protein product; urinar; urinary stone protein; Uropontin
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Osteopontin
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P10451
Gene Symbols:
SPP1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6696
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
2F10
Conjugate:
Unconjugated
Gene:
SPP1
Gene Alias:
2AR; 2b7; 44 kDa bone phosphoprotein; Apl-1; BNSP; Bone sialoprotein 1; Bone sialoprotein 1 (BSPI/BSP1); Bsp; BSPI; Calcium oxalate crystal growth inhibitor protein; CALPHA1 fusion; Early T lymphocyte activation 1 (ETA1); early T-lymphocyte activation 1; early T-lymphocyte activation 1 protein; Eta; ETA-1; HGNC:11255; immunoglobulin alpha 1 heavy chain constant region fusion protein; MGC110940; Minopontin; nephropontin; Op; Opn; Opnl; OSP; osteopontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; osteopontin-like protein; PSEC0156; Ric; Secreted phosphoprotein 1; secreted phosphoprotein 1 (osteopontin bone sialoprotein I early T lymphocyte activation 1); secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); Secreted phosphoprotein 1 (SPP1); secreted phosphoprotein 1 variant 6; Sialoprotein (osteopontin); SPP1; SPP-1; SPP1/CALPHA1 fusion; unnamed protein product; urinar; urinary stone protein; Uropontin
Host Species:
Mouse
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD289 (TLR9)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9NR96
Gene Symbols: Tlr9
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54106
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: eB72-1665
Conjugate: Unconjugated
Gene: Tlr9
Gene Alias: CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605
Host Species: Rat
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD289 (TLR9)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9NR96
Gene Symbols:
Tlr9
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54106
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
eB72-1665
Conjugate:
Unconjugated
Gene:
Tlr9
Gene Alias:
CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605
Host Species:
Rat
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ