14-979-082
SPI-B Monoclonal Antibody (235D), eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 14-979-082-Each-of-1 | In Stock | ₹ 36,790.80 |
14-979-082 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,790.80
GST (18%): ₹ 6,622.344
Total Price: ₹ 43,413.144
Antigen
SPI-B
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q01892
Gene Symbols
SPIB
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6689
Content And Storage
4° C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
235D
Conjugate
Unconjugated
Gene
SPIB
Gene Alias
B42b-like; Ets transcription factor Spi-B; Spi-1/PU.1 related; Spib; SPI-B; Spi-B transcription factor; Spi-B transcription factor (Spi-1/PU.1 related); Transcription factor Spi-B
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The 235D monoclonal antibody recognizes human SPI-B
- SPI-B is a member of the ETS transcription factor family which is comprised of DNA binding proteins that function in lymphoid development and activity
- SPI-B binds the PU box, a purine-rich DNA sequence (5'-GAGGAA-3')
- SPI-B is expressed in mature B cells, immature T cells, plasmacytoid dendritic cells, and microfold cells (M cells) of the intestine
- In human tonsil tissue, high levels of SPI-B are expressed in plasmacytoid dendritic cells, while lower levels of expression are found in germinal center B cells
- Applications Reported: This 235D antibody has been reported for use in western blotting, immunohistochemical staining of formalin-fixed paraffin embedded tissue sections, microscopy, immunohistochemical staining, and immunocytochemistry
- Applications Tested: This 235D antibody has been tested by immunohistochemistry on formalin-fixed paraffin embedded human tissue using low pH antigen retrieval and can be used at less than or equal to 5 μg/mL
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Purity: Greater than 90%, as determined by SDS-PAGE
- Aggregation: Less than 10%, as determined by HPLC
- Filtration: 0.2 μm post-manufacturing filtered
- Spi-B is a transcription factor belonging to a subfamily of ETS transcription factors with a conserved ETS domain that mediates specific DNA binding
- Spi-B may form homotypic interactions and is known to interact with IRF4, CREBBP, EP300, SPI1/PU.1 related, JUN and TBP
- As a sequence specific transcriptional activator it binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer
- Two isoforms of Spi-B are reported
- Spi-B is usually expressed in plasmacytoid dendritic cells (pDCs), also known as type 2 DC precursors (pre-DC2) or natural interferon (IFN)-producing cells and promotes their development and block viral replication
- Spi-B is not expressed in T-cells or granulocytes but may be present in stem cell populations of the liver and B-cells where it helps in B-cell receptor (BCR) signaling, normal B-cell development and antigenic stimulation.
Compare Similar Items
Show Difference
Antigen: SPI-B
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q01892
Gene Symbols: SPIB
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6689
Content And Storage: 4° C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 235D
Conjugate: Unconjugated
Gene: SPIB
Gene Alias: B42b-like; Ets transcription factor Spi-B; Spi-1/PU.1 related; Spib; SPI-B; Spi-B transcription factor; Spi-B transcription factor (Spi-1/PU.1 related); Transcription factor Spi-B
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
SPI-B
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q01892
Gene Symbols:
SPIB
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6689
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
235D
Conjugate:
Unconjugated
Gene:
SPIB
Gene Alias:
B42b-like; Ets transcription factor Spi-B; Spi-1/PU.1 related; Spib; SPI-B; Spi-B transcription factor; Spi-B transcription factor (Spi-1/PU.1 related); Transcription factor Spi-B
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: TRAF-1
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q13077
Gene Symbols: TRAF1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7185
Content And Storage: 4° C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 1F3
Conjugate: Unconjugated
Gene: TRAF1
Gene Alias: 4732496E14Rik; EBI6; Epstein-Bar virus-induced protein 6; Epstein-Barr virus-induced protein 6; MGC:10353; TNF receptor associated factor 1; TNF receptor-associated factor 1; Traf1
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
TRAF-1
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q13077
Gene Symbols:
TRAF1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7185
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
1F3
Conjugate:
Unconjugated
Gene:
TRAF1
Gene Alias:
4732496E14Rik; EBI6; Epstein-Bar virus-induced protein 6; Epstein-Barr virus-induced protein 6; MGC:10353; TNF receptor associated factor 1; TNF receptor-associated factor 1; Traf1
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: hnRNP UL1
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9BUJ2
Gene Symbols: Hnrnpul1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11100
Content And Storage: 4° C, do not freeze
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: EAP 4A11
Conjugate: Unconjugated
Gene: Hnrnpul1
Gene Alias: Adenovirus early region 1B-associated protein 5; E130317O14Rik; E1B 55kDa associated protein 5; E1B-55 kDa-associated protein 5; E1BAP5; E1B-AP5; EIB-55kDa associated protein 5; heterogeneous nuclear ribonucleoprotein U like 1; heterogeneous nuclear ribonucleoprotein U-like 1; heterogeneous nuclear ribonucleoprotein U-like protein 1; Hnrnpul; Hnrnpul1; HNRPUL1; LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein U-like protein 1
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
hnRNP UL1
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9BUJ2
Gene Symbols:
Hnrnpul1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11100
Content And Storage:
4° C, do not freeze
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
EAP 4A11
Conjugate:
Unconjugated
Gene:
Hnrnpul1
Gene Alias:
Adenovirus early region 1B-associated protein 5; E130317O14Rik; E1B 55kDa associated protein 5; E1B-55 kDa-associated protein 5; E1BAP5; E1B-AP5; EIB-55kDa associated protein 5; heterogeneous nuclear ribonucleoprotein U like 1; heterogeneous nuclear ribonucleoprotein U-like 1; heterogeneous nuclear ribonucleoprotein U-like protein 1; Hnrnpul; Hnrnpul1; HNRPUL1; LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein U-like protein 1
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: Blood Group Antigen H (O) Type 1
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: __
Gene Symbols: __
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: 17-206
Conjugate: Unconjugated
Gene: __
Gene Alias: ABH; BG-H; BG-H1; group h
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG3
Antigen:
Blood Group Antigen H (O) Type 1
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
17-206
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
ABH; BG-H; BG-H1; group h
Host Species:
Mouse
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG3