17-986-642
Phospho-PLCG2 (Tyr759) Monoclonal Antibody (4NPRN4), APC, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 17-986-642-Each-of-1 | In Stock | ₹ 34,265.00 |
17-986-642 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,265.00
GST (18%): ₹ 6,167.70
Total Price: ₹ 40,432.70
Antigen
Phospho-PLCG2 (Tyr759)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P16885, Q8CIH5
Gene Symbols
Plcg2
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
234779, 5336
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
4NPRN4
Conjugate
APC
Gene
Plcg2
Gene Alias
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; APLAID; FCAS3; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-2; phospholipase C gamma 2; phospholipase C, gamma 2; phospholipase C, gamma 2 (phosphatidylinositol-specific); phospholipase C-gamma-2; Phospholipase C-IV; PLC gamma 2; PLC gamma2; PLC- gamma2; PLC gamma-2; PLCG2; Plcg-2; PLC-gamma; PLCgamma2; PLC-gamma-2; PLC-IV
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Applications Reported: This 4NPRN4 antibody has been reported for use in intracellular staining followed by flow cytometric analysis
- Applications Tested: This 4NPRN4 antibody has been pre-diluted and tested by intracellular staining followed by flow cytometric analysis of normal human peripheral blood cells
- This may be used at 5 μL (0.06 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser Phosphoinositide-specific phospholipase C (PLC) plays a crucial role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1,4,5-triphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate
- There are many mammalian PLC isozymes, including PLC beta1, PLC beta2, PLC beta3, PLC beta4, PLC gamma1, PLC gamma2, PLC delta1, PLC delta2 and PLCe
- PLC delta exists as four different isoforms
- PLC delta1, a calcium signal amplifier, is activated by an atypical GTP-binding protein
- In addition, PLC delta1 is an effector for GTP-binding protein transglutaminase II-mediated oxytocin receptor and alpha1B-adrenoreceptor signaling
- Mouse PLC delta1 is highly expressed in brain, heart, lung and testis
- PLC delta is abnormally accumulated in autopsied brains with Alzheimer's disease (AD), suggesting that it may play a role in the pathology of AD
- PLC delta2 is markedly expressed in type II intestinal metaplasia and in the adenocarcinoma
- When PLC delta2 is expressed in type I intestinal metaplasia, the metaplasia is generally considered benignant, yet evolves toward neoplastic transformation
- Thus, PLC delta2 expression may be a possible marker of gastric malignant transformation.
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Antigen: Phospho-PLCG2 (Tyr759)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P16885, Q8CIH5
Gene Symbols: Plcg2
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 234779, 5336
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 4NPRN4
Conjugate: APC
Gene: Plcg2
Gene Alias: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; APLAID; FCAS3; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-2; phospholipase C gamma 2; phospholipase C, gamma 2; phospholipase C, gamma 2 (phosphatidylinositol-specific); phospholipase C-gamma-2; Phospholipase C-IV; PLC gamma 2; PLC gamma2; PLC- gamma2; PLC gamma-2; PLCG2; Plcg-2; PLC-gamma; PLCgamma2; PLC-gamma-2; PLC-IV
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Phospho-PLCG2 (Tyr759)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P16885, Q8CIH5
Gene Symbols:
Plcg2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
234779, 5336
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
4NPRN4
Conjugate:
APC
Gene:
Plcg2
Gene Alias:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; APLAID; FCAS3; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-2; phospholipase C gamma 2; phospholipase C, gamma 2; phospholipase C, gamma 2 (phosphatidylinositol-specific); phospholipase C-gamma-2; Phospholipase C-IV; PLC gamma 2; PLC gamma2; PLC- gamma2; PLC gamma-2; PLCG2; Plcg-2; PLC-gamma; PLCgamma2; PLC-gamma-2; PLC-IV
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: __
Applications: __
Clone: __
Conjugate: __
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Host Species: __
Quantity: 500/Pk.
Primary or Secondary: __
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Product Type: Label
Isotype: __
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Concentration:
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Formulation:
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Gene Accession No.:
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Purification Method:
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Regulatory Status:
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Gene ID (Entrez):
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Content And Storage:
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Form:
__
Applications:
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Clone:
__
Conjugate:
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Gene:
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Gene Alias:
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Host Species:
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Quantity:
500/Pk.
Primary or Secondary:
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Target Species:
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Product Type:
Label
Isotype:
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Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: __
Applications: __
Clone: __
Conjugate: __
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Gene Alias: __
Host Species: __
Quantity: 500/Pk.
Primary or Secondary: __
Target Species: __
Product Type: Label
Isotype: __
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Gene Accession No.:
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Purification Method:
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Content And Storage:
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Form:
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Applications:
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Clone:
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Conjugate:
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Gene:
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Gene Alias:
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Host Species:
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Quantity:
500/Pk.
Primary or Secondary:
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Target Species:
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Product Type:
Label
Isotype:
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Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: __
Applications: __
Clone: __
Conjugate: __
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Gene Alias: __
Host Species: __
Quantity: 500/Pk.
Primary or Secondary: __
Target Species: __
Product Type: Label
Isotype: __
Antigen:
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Classification:
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Concentration:
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Formulation:
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Gene Accession No.:
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Gene Symbols:
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Purification Method:
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Regulatory Status:
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Gene ID (Entrez):
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Content And Storage:
__
Form:
__
Applications:
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Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Quantity:
500/Pk.
Primary or Secondary:
__
Target Species:
__
Product Type:
Label
Isotype:
__