200006817

IFN gamma Monoclonal Antibody (4S.B3), Brilliant Ultra Violet™ 496, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

IFN gamma

Concentration

5 μL/Test

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias

BoIFNG, cytokine, EGK_03901, gamma interferon, gamma interferon precursor, gamma-interferon, gamma-interferon precursor (AA -23 to 143), H-IFN-g, IFG, IFI, IFN gamma, IFN ?, Ifng, IFN-g, IFNG2, IFN-gamma, IFN-gamma precursor, IFN-y, IFN?, Immune interferon, interferon gamma, interferon gamma precursor, interferon gamma type 2, Interferon y, Interferon ?, interferon, gamma, interferon-gama, interferon-gamma, Interferon-gamma level, interferon-gamma precursor, Interferon?, M-IFN-g, R-IFN-g

Gene Symbols

IFNG

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Clone

4S.B3

Applications

Flow Cytometry

Conjugate

Brilliant Ultraviolet 496

Host Species

Mouse

Target Species

Human

Gene Accession No.

P01579

Gene ID (Entrez)

3458

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Gene

IFNG

Description

  • IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation factor, and immune interferon that is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines
  • IFN gamma is a dimeric protein consisting of two 146 amino acid subunits
  • IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa
  • On SDS-PAGE, IFN gamma appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation
  • The biological activity of the IFN gamma homodimer is highly species specific
  • Human IFN gamma does not show cross-reactivity with mouse
  • IFN gamma function includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes
  • IFN gamma is involved in cytokine regulation and also acts synergistically with other cytokines
  • Activation of IFN gamma takes place through binding of IFN gamma receptor I and II, and activating the JAK-STAT pathway
  • IFN gamma does not show any homology with IFN alpha or IFN beta but human IFN gamma shows about 40% sequence homology with mouse IFN gamma
  • IFN gamma is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN
  • IFN gamma gene mutations are associated with aplastic anemia.

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Fischer Scientific

200006817

Mouse Monoclonal Antibody...


Antigen:
IFN gamma

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
BoIFNG, cytokine, EGK_03901, gamma interferon, gamma interferon precursor, gamma-interferon, gamma-interferon precursor (AA -23 to 143), H-IFN-g, IFG, IFI, IFN gamma, IFN ?, Ifng, IFN-g, IFNG2, IFN-gamma, IFN-gamma precursor, IFN-y, IFN?, Immune interferon, interferon gamma, interferon gamma precursor, interferon gamma type 2, Interferon y, Interferon ?, interferon, gamma, interferon-gama, interferon-gamma, Interferon-gamma level, interferon-gamma precursor, Interferon?, M-IFN-g, R-IFN-g

Gene Symbols:
IFNG

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
4S.B3

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 496

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P01579

Gene ID (Entrez):
3458

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Gene:
IFNG

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Fischer Scientific

200006818

Rat Monoclonal Antibody...


Antigen:
iNOS

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
Hepatocyte NOS, hepatocytes, HEP-NOS, inducible nitric oxide synthase, inducible NO synthase, Inducible NOS, iNos, i-NOS, Inosl, MAC-NOS, macrophage NOS, nitric oxide synthase 2, nitric oxide synthase 2, inducible, nitric oxide synthase 2, inducible, macrophage, nitric oxide synthase 2A (inducible, hepatocytes), nitric oxide synthase, inducible, nitric oxide synthase, macrophage, nitric oxide synthase-inducible, NOS, NOS type II, NOS, type II, Nos2, Nos-2, Nos2a, NOS-II, OTTMUSP00000000202, peptidyl-cysteine S-nitrosylase NOS2

Gene Symbols:
Nos2

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
CXNFT

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 395

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P29477

Gene ID (Entrez):
18126

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Gene:
Nos2

Img

Fischer Scientific

200006818

Rat Monoclonal Antibody...


Antigen:
iNOS

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
Hepatocyte NOS, hepatocytes, HEP-NOS, inducible nitric oxide synthase, inducible NO synthase, Inducible NOS, iNos, i-NOS, Inosl, MAC-NOS, macrophage NOS, nitric oxide synthase 2, nitric oxide synthase 2, inducible, nitric oxide synthase 2, inducible, macrophage, nitric oxide synthase 2A (inducible, hepatocytes), nitric oxide synthase, inducible, nitric oxide synthase, macrophage, nitric oxide synthase-inducible, NOS, NOS type II, NOS, type II, Nos2, Nos-2, Nos2a, NOS-II, OTTMUSP00000000202, peptidyl-cysteine S-nitrosylase NOS2

Gene Symbols:
Nos2

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
CXNFT

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 395

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P29477

Gene ID (Entrez):
18126

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Gene:
Nos2

Img

Fischer Scientific

200006820

Rat Monoclonal Antibody...


Antigen:
iNOS

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
Hepatocyte NOS, hepatocytes, HEP-NOS, inducible nitric oxide synthase, inducible NO synthase, Inducible NOS, iNos, i-NOS, Inosl, MAC-NOS, macrophage NOS, nitric oxide synthase 2, nitric oxide synthase 2, inducible, nitric oxide synthase 2, inducible, macrophage, nitric oxide synthase 2A (inducible, hepatocytes), nitric oxide synthase, inducible, nitric oxide synthase, macrophage, nitric oxide synthase-inducible, NOS, NOS type II, NOS, type II, Nos2, Nos-2, Nos2a, NOS-II, OTTMUSP00000000202, peptidyl-cysteine S-nitrosylase NOS2

Gene Symbols:
Nos2

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Clone:
CXNFT

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 615

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P29477

Gene ID (Entrez):
18126

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Gene:
Nos2