200006818
iNOS Monoclonal Antibody (CXNFT), Brilliant Ultra Violet™ 395, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
iNOS
Concentration
0.2 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias
Hepatocyte NOS, hepatocytes, HEP-NOS, inducible nitric oxide synthase, inducible NO synthase, Inducible NOS, iNos, i-NOS, Inosl, MAC-NOS, macrophage NOS, nitric oxide synthase 2, nitric oxide synthase 2, inducible, nitric oxide synthase 2, inducible, macrophage, nitric oxide synthase 2A (inducible, hepatocytes), nitric oxide synthase, inducible, nitric oxide synthase, macrophage, nitric oxide synthase-inducible, NOS, NOS type II, NOS, type II, Nos2, Nos-2, Nos2a, NOS-II, OTTMUSP00000000202, peptidyl-cysteine S-nitrosylase NOS2
Gene Symbols
Nos2
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Clone
CXNFT
Applications
Flow Cytometry
Conjugate
Brilliant Ultraviolet 395
Host Species
Rat
Target Species
Mouse
Gene Accession No.
P29477
Gene ID (Entrez)
18126
Isotype
IgG2a κ
Purification Method
Affinity chromatography
Gene
Nos2
Description
- iNOS (Inducible Nitric oxide, NO, NOS) is an inorganic, gaseous free radical that carries a variety of messages between cells
- Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO
- NO production is mediated by members of the nitric oxide synthase (NOS) family
- iNOS is expressed in liver and inducible by a combination of lipopolysaccharide and certain cytokines
- NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO
- Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) and endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned
- All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains
- iNOS is found in a variety of cell types including macrophages, hepatocytes, synoviocytes, and smooth muscle cells
- Cytokines such as interferon-gamma (IFN), tumor necrosis factor (TNF), interleukin-1 and -2, and lipopolysaccarides (LPS) cause an increase in iNOS mRNA, protein, and activity levels
- Protein kinase C-stimulating agents exhibit the same effect on iNOS activity
- After cytokine induction, iNOS exhibits a delayed activity response which is then followed by a significant increase in NO production over a long period of time
- Three related iNOS pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17
- Diseases associated with iNOS dysfunction include achalasia and impotence.
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Antigen: iNOS
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias: Hepatocyte NOS, hepatocytes, HEP-NOS, inducible nitric oxide synthase, inducible NO synthase, Inducible NOS, iNos, i-NOS, Inosl, MAC-NOS, macrophage NOS, nitric oxide synthase 2, nitric oxide synthase 2, inducible, nitric oxide synthase 2, inducible, macrophage, nitric oxide synthase 2A (inducible, hepatocytes), nitric oxide synthase, inducible, nitric oxide synthase, macrophage, nitric oxide synthase-inducible, NOS, NOS type II, NOS, type II, Nos2, Nos-2, Nos2a, NOS-II, OTTMUSP00000000202, peptidyl-cysteine S-nitrosylase NOS2
Gene Symbols: Nos2
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Clone: CXNFT
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 395
Host Species: Rat
Target Species: Mouse
Gene Accession No.: P29477
Gene ID (Entrez): 18126
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: Nos2
Antigen:
iNOS
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
Hepatocyte NOS, hepatocytes, HEP-NOS, inducible nitric oxide synthase, inducible NO synthase, Inducible NOS, iNos, i-NOS, Inosl, MAC-NOS, macrophage NOS, nitric oxide synthase 2, nitric oxide synthase 2, inducible, nitric oxide synthase 2, inducible, macrophage, nitric oxide synthase 2A (inducible, hepatocytes), nitric oxide synthase, inducible, nitric oxide synthase, macrophage, nitric oxide synthase-inducible, NOS, NOS type II, NOS, type II, Nos2, Nos-2, Nos2a, NOS-II, OTTMUSP00000000202, peptidyl-cysteine S-nitrosylase NOS2
Gene Symbols:
Nos2
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Clone:
CXNFT
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 395
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
P29477
Gene ID (Entrez):
18126
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
Nos2
Antigen: iNOS
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias: Hepatocyte NOS, hepatocytes, HEP-NOS, inducible nitric oxide synthase, inducible NO synthase, Inducible NOS, iNos, i-NOS, Inosl, MAC-NOS, macrophage NOS, nitric oxide synthase 2, nitric oxide synthase 2, inducible, nitric oxide synthase 2, inducible, macrophage, nitric oxide synthase 2A (inducible, hepatocytes), nitric oxide synthase, inducible, nitric oxide synthase, macrophage, nitric oxide synthase-inducible, NOS, NOS type II, NOS, type II, Nos2, Nos-2, Nos2a, NOS-II, OTTMUSP00000000202, peptidyl-cysteine S-nitrosylase NOS2
Gene Symbols: Nos2
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Clone: CXNFT
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 615
Host Species: Rat
Target Species: Mouse
Gene Accession No.: P29477
Gene ID (Entrez): 18126
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: Nos2
Antigen:
iNOS
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
Hepatocyte NOS, hepatocytes, HEP-NOS, inducible nitric oxide synthase, inducible NO synthase, Inducible NOS, iNos, i-NOS, Inosl, MAC-NOS, macrophage NOS, nitric oxide synthase 2, nitric oxide synthase 2, inducible, nitric oxide synthase 2, inducible, macrophage, nitric oxide synthase 2A (inducible, hepatocytes), nitric oxide synthase, inducible, nitric oxide synthase, macrophage, nitric oxide synthase-inducible, NOS, NOS type II, NOS, type II, Nos2, Nos-2, Nos2a, NOS-II, OTTMUSP00000000202, peptidyl-cysteine S-nitrosylase NOS2
Gene Symbols:
Nos2
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Clone:
CXNFT
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 615
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
P29477
Gene ID (Entrez):
18126
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
Nos2
Antigen: iNOS
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias: Hepatocyte NOS, hepatocytes, HEP-NOS, inducible nitric oxide synthase, inducible NO synthase, Inducible NOS, iNos, i-NOS, Inosl, MAC-NOS, macrophage NOS, nitric oxide synthase 2, nitric oxide synthase 2, inducible, nitric oxide synthase 2, inducible, macrophage, nitric oxide synthase 2A (inducible, hepatocytes), nitric oxide synthase, inducible, nitric oxide synthase, macrophage, nitric oxide synthase-inducible, NOS, NOS type II, NOS, type II, Nos2, Nos-2, Nos2a, NOS-II, OTTMUSP00000000202, peptidyl-cysteine S-nitrosylase NOS2
Gene Symbols: Nos2
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Clone: CXNFT
Applications: Flow Cytometry
Conjugate: Brilliant Violet 480
Host Species: Rat
Target Species: Mouse
Gene Accession No.: P29477
Gene ID (Entrez): 18126
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: Nos2
Antigen:
iNOS
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
Hepatocyte NOS, hepatocytes, HEP-NOS, inducible nitric oxide synthase, inducible NO synthase, Inducible NOS, iNos, i-NOS, Inosl, MAC-NOS, macrophage NOS, nitric oxide synthase 2, nitric oxide synthase 2, inducible, nitric oxide synthase 2, inducible, macrophage, nitric oxide synthase 2A (inducible, hepatocytes), nitric oxide synthase, inducible, nitric oxide synthase, macrophage, nitric oxide synthase-inducible, NOS, NOS type II, NOS, type II, Nos2, Nos-2, Nos2a, NOS-II, OTTMUSP00000000202, peptidyl-cysteine S-nitrosylase NOS2
Gene Symbols:
Nos2
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Clone:
CXNFT
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 480
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
P29477
Gene ID (Entrez):
18126
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
Nos2
Antigen: iNOS
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias: Hepatocyte NOS, hepatocytes, HEP-NOS, inducible nitric oxide synthase, inducible NO synthase, Inducible NOS, iNos, i-NOS, Inosl, MAC-NOS, macrophage NOS, nitric oxide synthase 2, nitric oxide synthase 2, inducible, nitric oxide synthase 2, inducible, macrophage, nitric oxide synthase 2A (inducible, hepatocytes), nitric oxide synthase, inducible, nitric oxide synthase, macrophage, nitric oxide synthase-inducible, NOS, NOS type II, NOS, type II, Nos2, Nos-2, Nos2a, NOS-II, OTTMUSP00000000202, peptidyl-cysteine S-nitrosylase NOS2
Gene Symbols: Nos2
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Clone: CXNFT
Applications: Flow Cytometry
Conjugate: Brilliant Violet 786
Host Species: Rat
Target Species: Mouse
Gene Accession No.: P29477
Gene ID (Entrez): 18126
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: Nos2
Antigen:
iNOS
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
Hepatocyte NOS, hepatocytes, HEP-NOS, inducible nitric oxide synthase, inducible NO synthase, Inducible NOS, iNos, i-NOS, Inosl, MAC-NOS, macrophage NOS, nitric oxide synthase 2, nitric oxide synthase 2, inducible, nitric oxide synthase 2, inducible, macrophage, nitric oxide synthase 2A (inducible, hepatocytes), nitric oxide synthase, inducible, nitric oxide synthase, macrophage, nitric oxide synthase-inducible, NOS, NOS type II, NOS, type II, Nos2, Nos-2, Nos2a, NOS-II, OTTMUSP00000000202, peptidyl-cysteine S-nitrosylase NOS2
Gene Symbols:
Nos2
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Clone:
CXNFT
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 786
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
P29477
Gene ID (Entrez):
18126
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
Nos2