200008611
Arginase 1 Monoclonal Antibody (A1exF5), Brilliant Violet™ 480, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
Arginase 1
Concentration
0.2 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias
AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase
Gene Symbols
ARG1
Isotype
IgG2a κ
Purification Method
Affinity chromatography
Gene
ARG1
Clone
A1exF5
Applications
Flow Cytometry
Conjugate
Brilliant Violet 480
Host Species
Rat
Target Species
Human, Mouse
Gene Accession No.
P05089, Q61176
Gene ID (Entrez)
11846, 383
Immunogen
E.coli-derived recombinant mouse Arginase 1
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Description
- Arginase-1 (Arg1) is a 35 kDa enzyme converting L-arginine to urea and L-ornithine, which is the final step in the urea cycle
- The resulting polyamines are important for cell proliferation and removal of toxins that arise from protein degradation
- By degrading arginine, Arginase 1 deprives NO synthase of its substrate and down-regulates nitric oxide production
- In both human and mouse, Arginase 1 is expressed in the liver, neutrophils, myeloid derived suppressor cells (MDSC) and neural stem cells
- In human, expression in blood neutrophils but not in CCR3+ granulocytes has been reported
- In mice, expression of Arginase 1 is one of the hallmarks of alternatively activated macrophages (M2a)
- Arginase-1 may be expressed in the myeloid cells infiltrating tumors, and is typically found in the majority of hepatocellular carcinomas
- Defects in Arginase 1 are the cause of argininemia, an autosomal recessive disorder characterized by hyperammonemia.
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Antigen: Arginase 1
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias: AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase
Gene Symbols: ARG1
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: ARG1
Clone: A1exF5
Applications: Flow Cytometry
Conjugate: Brilliant Violet 480
Host Species: Rat
Target Species: Human, Mouse
Gene Accession No.: P05089, Q61176
Gene ID (Entrez): 11846, 383
Immunogen: E.coli-derived recombinant mouse Arginase 1
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Antigen:
Arginase 1
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase
Gene Symbols:
ARG1
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
ARG1
Clone:
A1exF5
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 480
Host Species:
Rat
Target Species:
Human, Mouse
Gene Accession No.:
P05089, Q61176
Gene ID (Entrez):
11846, 383
Immunogen:
E.coli-derived recombinant mouse Arginase 1
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Antigen: CD68
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias: CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
Gene Symbols: Cd68
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: Cd68
Clone: FA-11
Applications: Flow Cytometry
Conjugate: Brilliant Violet 786
Host Species: Rat
Target Species: Mouse
Gene Accession No.: P31996
Gene ID (Entrez): 12514
Immunogen: __
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Antigen:
CD68
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
Gene Symbols:
Cd68
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
Cd68
Clone:
FA-11
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 786
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
P31996
Gene ID (Entrez):
12514
Immunogen:
__
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Antigen: Arginase 1
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias: AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase
Gene Symbols: ARG1
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: ARG1
Clone: A1exF5
Applications: Flow Cytometry
Conjugate: Brilliant Violet 650
Host Species: Rat
Target Species: Human, Mouse
Gene Accession No.: P05089, Q61176
Gene ID (Entrez): 11846, 383
Immunogen: E.coli-derived recombinant mouse Arginase 1
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Antigen:
Arginase 1
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase
Gene Symbols:
ARG1
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
ARG1
Clone:
A1exF5
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 650
Host Species:
Rat
Target Species:
Human, Mouse
Gene Accession No.:
P05089, Q61176
Gene ID (Entrez):
11846, 383
Immunogen:
E.coli-derived recombinant mouse Arginase 1
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Antigen: Arginase 1
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias: AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase
Gene Symbols: ARG1
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: ARG1
Clone: A1exF5
Applications: Flow Cytometry
Conjugate: Brilliant Violet 650
Host Species: Rat
Target Species: Human, Mouse
Gene Accession No.: P05089, Q61176
Gene ID (Entrez): 11846, 383
Immunogen: E.coli-derived recombinant mouse Arginase 1
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Antigen:
Arginase 1
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase
Gene Symbols:
ARG1
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
ARG1
Clone:
A1exF5
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 650
Host Species:
Rat
Target Species:
Human, Mouse
Gene Accession No.:
P05089, Q61176
Gene ID (Entrez):
11846, 383
Immunogen:
E.coli-derived recombinant mouse Arginase 1
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!