200008623

Arginase 1 Monoclonal Antibody (A1exF5), Brilliant Violet™ 650, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Arginase 1

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias

AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase

Gene Symbols

ARG1

Isotype

IgG2a κ

Purification Method

Affinity chromatography

Gene

ARG1

Clone

A1exF5

Applications

Flow Cytometry

Conjugate

Brilliant Violet 650

Host Species

Rat

Target Species

Human, Mouse

Gene Accession No.

P05089, Q61176

Gene ID (Entrez)

11846, 383

Immunogen

E.coli-derived recombinant mouse Arginase 1

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

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Description

  • Arginase-1 (Arg1) is a 35 kDa enzyme converting L-arginine to urea and L-ornithine, which is the final step in the urea cycle
  • The resulting polyamines are important for cell proliferation and removal of toxins that arise from protein degradation
  • By degrading arginine, Arginase 1 deprives NO synthase of its substrate and down-regulates nitric oxide production
  • In both human and mouse, Arginase 1 is expressed in the liver, neutrophils, myeloid derived suppressor cells (MDSC) and neural stem cells
  • In human, expression in blood neutrophils but not in CCR3+ granulocytes has been reported
  • In mice, expression of Arginase 1 is one of the hallmarks of alternatively activated macrophages (M2a)
  • Arginase-1 may be expressed in the myeloid cells infiltrating tumors, and is typically found in the majority of hepatocellular carcinomas
  • Defects in Arginase 1 are the cause of argininemia, an autosomal recessive disorder characterized by hyperammonemia.

Compare Similar Items

Show Difference

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Fischer Scientific

200008623

Rat Monoclonal Antibody...


Antigen:
Arginase 1

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase

Gene Symbols:
ARG1

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Gene:
ARG1

Clone:
A1exF5

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 650

Host Species:
Rat

Target Species:
Human, Mouse

Gene Accession No.:
P05089, Q61176

Gene ID (Entrez):
11846, 383

Immunogen:
E.coli-derived recombinant mouse Arginase 1

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

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Fischer Scientific

200008624

Mouse Monoclonal Antibody...


Antigen:
CD45

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220

Gene Symbols:
PTPRC

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Gene:
PTPRC

Clone:
HI30

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 605

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P08575

Gene ID (Entrez):
5788

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

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200008625

Rat Monoclonal Antibody...


Antigen:
CD24

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
CD24; CD24 antigen; CD24 antigen (small cell lung carcinoma cluster 4 antigen); CD24 molecule; CD24A; CD24a antigen; cluster of differentiation 24; FLJ22950; FLJ43543; heat stable antigen; heat-stable antigen; HSA; Ly-52; Lymphocyte antigen 52; M1/69-J11D heat stable antigen; MGC75043; Nectadrin; nectadrin heat stable antigen; R13-Ag; Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen; X62 heat stable antigen

Gene Symbols:
Cd24a

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Gene:
Cd24a

Clone:
M1/69

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 711

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P24807

Gene ID (Entrez):
12484

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

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200008626

Rat Monoclonal Antibody...


Antigen:
CD326 (EpCAM)

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
adenocarcinoma-associated antigen; CD326; cell surface glycoprotein Trop-1; DIAR5; EGP; EGP-2; EGP314; EGP40; EPCAM; Ep-CAM; EpCAM1; epithelial cell adhesion molecule; Epithelial cell surface antigen; Epithelial glycoprotein; Epithelial glycoprotein 314; ESA; GA733-2; gp40; hEGP314; HNPCC8; human epithelial glycoprotein-2; KS 1/4 antigen; KS1/4; KSA; Ly74; lymphocyte antigen 74; M1S2; M4S1; major gastrointestinal tumor-associated protein GA733-2; mEGP314; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; panepithelial glycoprotein 314; protein 289A; Protein D5.7A; Tacsd1; Tacstd1; TROP1; Trop-1 protein; Tumor-associated calcium signal transducer 1

Gene Symbols:
EPCAM

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Gene:
EPCAM

Clone:
G8.8

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 786

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
Q99JW5

Gene ID (Entrez):
17075

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!