200008731
ZO-1 Recombinant Mouse Monoclonal Antibody (ZO1-1A12), Invitrogen™
Mouse Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
ZO-1
Concentration
1.0 mg/mL
Classification
Recombinant Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.09% sodium azide; pH 7.4
Gene Alias
DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1
Gene Symbols
TJP1
Isotype
IgG1 κ
Purification Method
Protein A/G
Gene
TJP1
Clone
ZO1-1A12
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human, Mouse
Gene Accession No.
P39447, Q07157
Gene ID (Entrez)
21872, 7082
Immunogen
Human recombinant ZO-1 fusion protein encompassing amino acids 334-634
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
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Description
- Recombinant mouse monoclonal antibodies are produced using in vitro expression systems
- Recombinant antibodies are produced using specific genes that code for the desired antibodies
- These genes are cloned into an expression vector and expressed in vitro
- The advantages of recombinant antibodies include better specificity and lot-to-lot consistency
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- ZO-1 forms complexes with either ZO-2 or ZO-3
- In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction
- ZO-1 expression is significantly reduced in many breast cancer lines
- ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue
- ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions
- ZO-1 may be involved in signal transduction at cell-cell junctions
- Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene
- Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.
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Antigen: ZO-1
Concentration: 1.0 mg/mL
Classification: Recombinant Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Alias: DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1
Gene Symbols: TJP1
Isotype: IgG1 κ
Purification Method: Protein A/G
Gene: TJP1
Clone: ZO1-1A12
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Mouse
Gene Accession No.: P39447, Q07157
Gene ID (Entrez): 21872, 7082
Immunogen: Human recombinant ZO-1 fusion protein encompassing amino acids 334-634
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen:
ZO-1
Concentration:
1.0 mg/mL
Classification:
Recombinant Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Alias:
DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1
Gene Symbols:
TJP1
Isotype:
IgG1 κ
Purification Method:
Protein A/G
Gene:
TJP1
Clone:
ZO1-1A12
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Mouse
Gene Accession No.:
P39447, Q07157
Gene ID (Entrez):
21872, 7082
Immunogen:
Human recombinant ZO-1 fusion protein encompassing amino acids 334-634
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen: GST
Concentration: 1.0 mg/mL
Classification: Recombinant Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Alias: activator protein 1; AP1; AP-1; cancer/testis antigen 48; c-Jun; CT48; deafness, X-linked 7; DFN7; enhancer-binding protein AP1; epididymis secretory protein Li 22; FAEES3; fatty acid ethyl ester synthase III; glutathione S-alkyltransferase; glutathione S-aralkyltransferase; glutathione S-aryltransferase; glutathione S-transferase M1; glutathione S-transferase mu 1; Glutathione S-transferase P; glutathione S-transferase pi 1; Glutathione-S-Transferase; gonad-specific transporter; GST; GST class-mu 1; GST class-pi; GST HB subunit 4; GST protein; GST Tag; GST1; GST3; GSTM1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GSTP; GSTP1; GSTP1-1; GTH4; GTM1; H-B; HB subunit 4; HEL-S-22; JUN; Jun activation domain binding protein; jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; MU; MU-1; OATP6A1; OATP-I; OATPY; Organic anion-transporting polypeptide 6A1; Organic anion-transporting polypeptide I; p39; PI; Proto-oncogene c-Jun; S-(hydroxyalkyl)glutathione lyase; SLC21A19; SLCO6A1; Solute carrier family 21 member 19; solute carrier organic anion transporter family member 6A1; solute carrier organic anion transporter family, member 6A1; testicular tissue protein Li 174; testis-specific organic anion transporter; transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog
Gene Symbols: __
Isotype: IgG2b κ
Purification Method: Protein A/G
Gene: __
Clone: GST 3-4C
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Tag
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: GST protein from Schistosoma japonicum expressed from the pGEX vector.
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen:
GST
Concentration:
1.0 mg/mL
Classification:
Recombinant Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Alias:
activator protein 1; AP1; AP-1; cancer/testis antigen 48; c-Jun; CT48; deafness, X-linked 7; DFN7; enhancer-binding protein AP1; epididymis secretory protein Li 22; FAEES3; fatty acid ethyl ester synthase III; glutathione S-alkyltransferase; glutathione S-aralkyltransferase; glutathione S-aryltransferase; glutathione S-transferase M1; glutathione S-transferase mu 1; Glutathione S-transferase P; glutathione S-transferase pi 1; Glutathione-S-Transferase; gonad-specific transporter; GST; GST class-mu 1; GST class-pi; GST HB subunit 4; GST protein; GST Tag; GST1; GST3; GSTM1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GSTP; GSTP1; GSTP1-1; GTH4; GTM1; H-B; HB subunit 4; HEL-S-22; JUN; Jun activation domain binding protein; jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; MU; MU-1; OATP6A1; OATP-I; OATPY; Organic anion-transporting polypeptide 6A1; Organic anion-transporting polypeptide I; p39; PI; Proto-oncogene c-Jun; S-(hydroxyalkyl)glutathione lyase; SLC21A19; SLCO6A1; Solute carrier family 21 member 19; solute carrier organic anion transporter family member 6A1; solute carrier organic anion transporter family, member 6A1; testicular tissue protein Li 174; testis-specific organic anion transporter; transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog
Gene Symbols:
__
Isotype:
IgG2b κ
Purification Method:
Protein A/G
Gene:
__
Clone:
GST 3-4C
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Tag
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
GST protein from Schistosoma japonicum expressed from the pGEX vector.
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen: GST
Concentration: 1.0 mg/mL
Classification: Recombinant Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Alias: activator protein 1; AP1; AP-1; cancer/testis antigen 48; c-Jun; CT48; deafness, X-linked 7; DFN7; enhancer-binding protein AP1; epididymis secretory protein Li 22; FAEES3; fatty acid ethyl ester synthase III; glutathione S-alkyltransferase; glutathione S-aralkyltransferase; glutathione S-aryltransferase; glutathione S-transferase M1; glutathione S-transferase mu 1; Glutathione S-transferase P; glutathione S-transferase pi 1; Glutathione-S-Transferase; gonad-specific transporter; GST; GST class-mu 1; GST class-pi; GST HB subunit 4; GST protein; GST Tag; GST1; GST3; GSTM1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GSTP; GSTP1; GSTP1-1; GTH4; GTM1; H-B; HB subunit 4; HEL-S-22; JUN; Jun activation domain binding protein; jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; MU; MU-1; OATP6A1; OATP-I; OATPY; Organic anion-transporting polypeptide 6A1; Organic anion-transporting polypeptide I; p39; PI; Proto-oncogene c-Jun; S-(hydroxyalkyl)glutathione lyase; SLC21A19
Gene Symbols: __
Isotype: IgG2b κ
Purification Method: Protein A/G
Gene: __
Clone: GST 3-4C
Applications: Western Blot
Conjugate: Biotin
Host Species: Mouse
Target Species: Tag
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: GST protein from Schistosoma japonicum expressed from the pGEX vector.
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Antigen:
GST
Concentration:
1.0 mg/mL
Classification:
Recombinant Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Alias:
activator protein 1; AP1; AP-1; cancer/testis antigen 48; c-Jun; CT48; deafness, X-linked 7; DFN7; enhancer-binding protein AP1; epididymis secretory protein Li 22; FAEES3; fatty acid ethyl ester synthase III; glutathione S-alkyltransferase; glutathione S-aralkyltransferase; glutathione S-aryltransferase; glutathione S-transferase M1; glutathione S-transferase mu 1; Glutathione S-transferase P; glutathione S-transferase pi 1; Glutathione-S-Transferase; gonad-specific transporter; GST; GST class-mu 1; GST class-pi; GST HB subunit 4; GST protein; GST Tag; GST1; GST3; GSTM1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GSTP; GSTP1; GSTP1-1; GTH4; GTM1; H-B; HB subunit 4; HEL-S-22; JUN; Jun activation domain binding protein; jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; MU; MU-1; OATP6A1; OATP-I; OATPY; Organic anion-transporting polypeptide 6A1; Organic anion-transporting polypeptide I; p39; PI; Proto-oncogene c-Jun; S-(hydroxyalkyl)glutathione lyase; SLC21A19
Gene Symbols:
__
Isotype:
IgG2b κ
Purification Method:
Protein A/G
Gene:
__
Clone:
GST 3-4C
Applications:
Western Blot
Conjugate:
Biotin
Host Species:
Mouse
Target Species:
Tag
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
GST protein from Schistosoma japonicum expressed from the pGEX vector.
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Antigen: CD28
Concentration: 1.0 mg/mL
Classification: Recombinant Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone; pH 6.5
Gene Alias: antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Gene Symbols: Cd28
Isotype: IgG1 κ
Purification Method: Protein A/G
Gene: Cd28
Clone: CD28.2
Applications: Flow Cytometry
Conjugate: Alexa Fluor Plus 488
Host Species: Mouse
Target Species: Human
Gene Accession No.: P10747
Gene ID (Entrez): 940
Immunogen: __
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Antigen:
CD28
Concentration:
1.0 mg/mL
Classification:
Recombinant Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone; pH 6.5
Gene Alias:
antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Gene Symbols:
Cd28
Isotype:
IgG1 κ
Purification Method:
Protein A/G
Gene:
Cd28
Clone:
CD28.2
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor Plus 488
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P10747
Gene ID (Entrez):
940
Immunogen:
__
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!