50-253-9565

Occludin Recombinant Mouse Monoclonal Antibody (OC-3F10), Alexa Fluor™ Plus 647, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-253-9565-Each-of-1 In Stock ₹ 12,748.44

50-253-9565 - Each of 1

₹ 12,748.44

In Stock

Quantity

1

Base Price: ₹ 12,748.44

GST (18%): ₹ 2,294.719

Total Price: ₹ 15,043.159

Antigen

Occludin

Classification

Recombinant Monoclonal

Concentration

1.0 mg/mL

Formulation

proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5

Gene Accession No.

Q16625

Gene Symbols

OCLN

Immunogen

GST fusion protein consisting of the C-terminal region (∽150aa) of human occludin.

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry

Clone

OC-3F10

Conjugate

Alexa Fluor Plus 647

Gene

OCLN

Gene Alias

AI503564, BLCPMG, Occludin, occludin 1B, Ocl, Ocln, phosphatase 1, regulatory subunit 115, PPP1R115, tight junction protein occludin, tight junction structural protein

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

100506658

Content And Storage

4°, C, store in dark, DO NOT FREEZE!

Isotype

IgG1 κ

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Description

  • Description Occludin is a 65 kDa protein that can exist in a variety of phosphorylated forms, ranging up to approximately 82 kDa
  • Occludin is thought to be involved in regulating both the localization and the function of occludin
  • Polyunsaturated fatty acids are known to up-regulate occludin expression, increasing the transendothelial cell resistance and reducing the cellular permeability to large molecules
  • The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly and continuously expressed at cell-cell contact sites, whereas non-neural tissues show lower expression and discontinuous distribution
  • Overall structural features of the occludin protein are highly conserved in all the species examined
  • Under-expression of tight junction proteins, including occludin, is a key molecular abnormality responsible for the increased permeability of tumor endothelial tight junctions, which contributes to brain tumor edemas.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-253-9565

--


Antigen:
Occludin

Classification:
Recombinant Monoclonal

Concentration:
1.0 mg/mL

Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5

Gene Accession No.:
Q16625

Gene Symbols:
OCLN

Immunogen:
GST fusion protein consisting of the C-terminal region (∽150aa) of human occludin.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry

Clone:
OC-3F10

Conjugate:
Alexa Fluor Plus 647

Gene:
OCLN

Gene Alias:
AI503564, BLCPMG, Occludin, occludin 1B, Ocl, Ocln, phosphatase 1, regulatory subunit 115, PPP1R115, tight junction protein occludin, tight junction structural protein

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100506658

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Isotype:
IgG1 κ

Img

Fischer Scientific

50-253-9566

--


Antigen:
Occludin

Classification:
Recombinant Monoclonal

Concentration:
1.0 mg/mL

Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5

Gene Accession No.:
Q16625

Gene Symbols:
OCLN

Immunogen:
GST fusion protein consisting of the C-terminal region (∽150aa) of human occludin.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry

Clone:
OC-3F10

Conjugate:
Alexa Fluor Plus 594

Gene:
OCLN

Gene Alias:
AI503564, BLCPMG, Occludin, occludin 1B, Ocl, Ocln, phosphatase 1, regulatory subunit 115, PPP1R115, tight junction protein occludin, tight junction structural protein

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100506658

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Isotype:
IgG1 κ

Img

Fischer Scientific

50-253-9567

--


Antigen:
ZO-1

Classification:
Recombinant Monoclonal

Concentration:
1.0 mg/mL

Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5

Gene Accession No.:
Q07157

Gene Symbols:
TJP1

Immunogen:
Human recombinant ZO-1 fusion protein encompassing amino acids 334-634

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
ZO1-1A12

Conjugate:
Alexa Fluor Plus 647

Gene:
TJP1

Gene Alias:
DKFZp686M05161, I79_005485, MGC133289, OTTHUMP00000174520, Tight junction protein 1, tight junction protein 1 (zona occludens 1), tight junction protein ZO-1, Tjp1, zo1, ZO-1, ZO-1 MDCK, zona occludens 1, zona occludens protein 1, zonula occludens 1, zonula occludens 1 protein, zonula occludens protein 1

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
7082

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Isotype:
IgG1

Img

Fischer Scientific

50-253-9568

--


Antigen:
ZO-1

Classification:
Recombinant Monoclonal

Concentration:
1.0 mg/mL

Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5

Gene Accession No.:
Q07157

Gene Symbols:
TJP1

Immunogen:
Human recombinant ZO-1 fusion protein encompassing amino acids 334-634

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
ZO1-1A12

Conjugate:
Alexa Fluor Plus 555

Gene:
TJP1

Gene Alias:
DKFZp686M05161, I79_005485, MGC133289, OTTHUMP00000174520, Tight junction protein 1, tight junction protein 1 (zona occludens 1), tight junction protein ZO-1, Tjp1, zo1, ZO-1, ZO-1 MDCK, zona occludens 1, zona occludens protein 1, zonula occludens 1, zonula occludens 1 protein, zonula occludens protein 1

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
7082

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Isotype:
IgG1