200020078
CD59 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
CD59
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse
Gene Accession No.
O55186, P13987, P58019
Gene ID (Entrez)
12509, 333883, 966
Immunogen
Recombinant Mouse CD59 protein, Val22-Ser96 (Accession #O55186)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration
0.5 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
16.3A5, 1F5, 1F5 antigen, 20 kDa homologous restriction factor, AA987121, Cb59b molecule, CD59, CD59 antigen, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344), CD59 glycoprotein, CD59 molecule, CD59 molecule (CD59 blood group), CD59 molecule, complement regulatory protein, Cd59a, CD59a antigen, CD59A glycoprotein, Cd59b, CD59b antigen, CD59B glycoprotein, CD59b moleucle, complement regulatory protein, complement inhibitor CD59, complement regulatory protein, EJ16, EJ30, EL32, G344, HRF20, HRF-20, human leukocyte antigen MIC11, Ly-6-like protein, lymphocytic antigen CD59/MEM43, MACIF, MAC-inhibitory protein, MACIP, MAC-IP, MEM43, MEM43 antigen, membrane attack complex (MAC) inhibition factor, membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20, protectin, surface anitgen recognized by monoclonal antibody 16.3A5, T cell-activating protein
Gene Symbols
CD59, Cd59a, Cd59b
Isotype
IgG
Purification Method
Protein A
Gene
CD59
Related Products
Description
- CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC)
- CD59 is the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade
- CD59 also associates with C5b-8 complex and counteracts appropriate formation of cytolytic pore within the plasma membrane
- Further, CD59 is a low-affinity ligand of human CD2, causes T cell costimulation, and is involved in lymphocyte signal transduction
- CD59 is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation
- Mutations in this gene cause CD59 deficiency, a disease involving hemolytic anemia, thrombosis, and cerebral infarction
- Multiple alternatively spliced transcript variants of CD59 have been identified.
Compare Similar Items
Show Difference
Antigen: CD59
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: O55186, P13987, P58019
Gene ID (Entrez): 12509, 333883, 966
Immunogen: Recombinant Mouse CD59 protein, Val22-Ser96 (Accession #O55186)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration: 0.5 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: 16.3A5, 1F5, 1F5 antigen, 20 kDa homologous restriction factor, AA987121, Cb59b molecule, CD59, CD59 antigen, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344), CD59 glycoprotein, CD59 molecule, CD59 molecule (CD59 blood group), CD59 molecule, complement regulatory protein, Cd59a, CD59a antigen, CD59A glycoprotein, Cd59b, CD59b antigen, CD59B glycoprotein, CD59b moleucle, complement regulatory protein, complement inhibitor CD59, complement regulatory protein, EJ16, EJ30, EL32, G344, HRF20, HRF-20, human leukocyte antigen MIC11, Ly-6-like protein, lymphocytic antigen CD59/MEM43, MACIF, MAC-inhibitory protein, MACIP, MAC-IP, MEM43, MEM43 antigen, membrane attack complex (MAC) inhibition factor, membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20, protectin, surface anitgen recognized by monoclonal antibody 16.3A5, T cell-activating protein
Gene Symbols: CD59, Cd59a, Cd59b
Isotype: IgG
Purification Method: Protein A
Gene: CD59
Antigen:
CD59
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
O55186, P13987, P58019
Gene ID (Entrez):
12509, 333883, 966
Immunogen:
Recombinant Mouse CD59 protein, Val22-Ser96 (Accession #O55186)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration:
0.5 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
16.3A5, 1F5, 1F5 antigen, 20 kDa homologous restriction factor, AA987121, Cb59b molecule, CD59, CD59 antigen, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344), CD59 glycoprotein, CD59 molecule, CD59 molecule (CD59 blood group), CD59 molecule, complement regulatory protein, Cd59a, CD59a antigen, CD59A glycoprotein, Cd59b, CD59b antigen, CD59B glycoprotein, CD59b moleucle, complement regulatory protein, complement inhibitor CD59, complement regulatory protein, EJ16, EJ30, EL32, G344, HRF20, HRF-20, human leukocyte antigen MIC11, Ly-6-like protein, lymphocytic antigen CD59/MEM43, MACIF, MAC-inhibitory protein, MACIP, MAC-IP, MEM43, MEM43 antigen, membrane attack complex (MAC) inhibition factor, membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20, protectin, surface anitgen recognized by monoclonal antibody 16.3A5, T cell-activating protein
Gene Symbols:
CD59, Cd59a, Cd59b
Isotype:
IgG
Purification Method:
Protein A
Gene:
CD59
Antigen: HAMP
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P81172
Gene ID (Entrez): 57817
Immunogen: Recombinant Human Hepc protein, Ser25-Thr84 (Accession #P81172)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: HAMP, Hamp1, HEPC, Hepc1, Hepc20, Hepc25, Hepcidin, hepcidin antimicrobial peptide, hepcidin antimicrobial peptide 1, Hepcidin-20, Hepcidin-25, HFE2B, LEAP1, LEAP-1, liver-expressed antimicrobial peptide 1, PLTR, Putative liver tumor regressor, UNQ487/PRO1003
Gene Symbols: HAMP
Isotype: IgG1 κ
Purification Method: Protein A/G
Gene: HAMP
Antigen:
HAMP
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P81172
Gene ID (Entrez):
57817
Immunogen:
Recombinant Human Hepc protein, Ser25-Thr84 (Accession #P81172)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
HAMP, Hamp1, HEPC, Hepc1, Hepc20, Hepc25, Hepcidin, hepcidin antimicrobial peptide, hepcidin antimicrobial peptide 1, Hepcidin-20, Hepcidin-25, HFE2B, LEAP1, LEAP-1, liver-expressed antimicrobial peptide 1, PLTR, Putative liver tumor regressor, UNQ487/PRO1003
Gene Symbols:
HAMP
Isotype:
IgG1 κ
Purification Method:
Protein A/G
Gene:
HAMP
Antigen: HAMP
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P81172
Gene ID (Entrez): 57817
Immunogen: Recombinant Human Hepc protein, Ser25-Thr84 (Accession #P81172)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: HAMP, Hamp1, HEPC, Hepc1, Hepc20, Hepc25, Hepcidin, hepcidin antimicrobial peptide, hepcidin antimicrobial peptide 1, Hepcidin-20, Hepcidin-25, HFE2B, LEAP1, LEAP-1, liver-expressed antimicrobial peptide 1, PLTR, Putative liver tumor regressor, UNQ487/PRO1003
Gene Symbols: HAMP
Isotype: IgG1 κ
Purification Method: Protein A/G
Gene: HAMP
Antigen:
HAMP
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P81172
Gene ID (Entrez):
57817
Immunogen:
Recombinant Human Hepc protein, Ser25-Thr84 (Accession #P81172)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
HAMP, Hamp1, HEPC, Hepc1, Hepc20, Hepc25, Hepcidin, hepcidin antimicrobial peptide, hepcidin antimicrobial peptide 1, Hepcidin-20, Hepcidin-25, HFE2B, LEAP1, LEAP-1, liver-expressed antimicrobial peptide 1, PLTR, Putative liver tumor regressor, UNQ487/PRO1003
Gene Symbols:
HAMP
Isotype:
IgG1 κ
Purification Method:
Protein A/G
Gene:
HAMP
Antigen: ATF6
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: F6VAN0, O35451, P18850, Q99941
Gene ID (Entrez): 12915, 1388, 226641, 22926
Immunogen: Recombinant Human ATF6 protein, Ala423-Asn646 (Accession #P18850)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration: 0.5 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: 9130025P16Rik, 9630036G24, AA617266, AA789574, ACHM7, activating transcription factor 6, activating transcription factor 6 alpha, Activating transcription factor 6 beta, ATF 6, Atf6, ATF6 alpha, ATF6A, Atf6alpha, ATF6-alpha, Atf6b, ATF6beta, ATF6-beta, cAMP response element binding protein-related protein, cAMP response element-binding protein-related protein, cAMP responsive element binding protein-like 1, cAMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 beta, cAMP-responsive element-binding protein-like 1, Crebl1, Creb-related protein, CREB-RP, Cyclic AMP-dependent transcription factor ATF-6 alpha, cyclic AMP-dependent transcription factor ATF-6 beta, DKFZp686P2194, ESTM49, FLJ21663, G13, Processed cyclic AMP-dependent transcription factor ATF-6 alpha, Processed cyclic AMP-dependent transcription factor ATF-6 beta, Protein G13
Gene Symbols: ATF6, ATF6B
Isotype: IgG
Purification Method: Protein A
Gene: ATF6
Antigen:
ATF6
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
F6VAN0, O35451, P18850, Q99941
Gene ID (Entrez):
12915, 1388, 226641, 22926
Immunogen:
Recombinant Human ATF6 protein, Ala423-Asn646 (Accession #P18850)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration:
0.5 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
9130025P16Rik, 9630036G24, AA617266, AA789574, ACHM7, activating transcription factor 6, activating transcription factor 6 alpha, Activating transcription factor 6 beta, ATF 6, Atf6, ATF6 alpha, ATF6A, Atf6alpha, ATF6-alpha, Atf6b, ATF6beta, ATF6-beta, cAMP response element binding protein-related protein, cAMP response element-binding protein-related protein, cAMP responsive element binding protein-like 1, cAMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 beta, cAMP-responsive element-binding protein-like 1, Crebl1, Creb-related protein, CREB-RP, Cyclic AMP-dependent transcription factor ATF-6 alpha, cyclic AMP-dependent transcription factor ATF-6 beta, DKFZp686P2194, ESTM49, FLJ21663, G13, Processed cyclic AMP-dependent transcription factor ATF-6 alpha, Processed cyclic AMP-dependent transcription factor ATF-6 beta, Protein G13
Gene Symbols:
ATF6, ATF6B
Isotype:
IgG
Purification Method:
Protein A
Gene:
ATF6