200020080
ATF6 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
ATF6
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse
Gene Accession No.
F6VAN0, O35451, P18850, Q99941
Gene ID (Entrez)
12915, 1388, 226641, 22926
Immunogen
Recombinant Human ATF6 protein, Ala423-Asn646 (Accession #P18850)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration
0.5 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
9130025P16Rik, 9630036G24, AA617266, AA789574, ACHM7, activating transcription factor 6, activating transcription factor 6 alpha, Activating transcription factor 6 beta, ATF 6, Atf6, ATF6 alpha, ATF6A, Atf6alpha, ATF6-alpha, Atf6b, ATF6beta, ATF6-beta, cAMP response element binding protein-related protein, cAMP response element-binding protein-related protein, cAMP responsive element binding protein-like 1, cAMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 beta, cAMP-responsive element-binding protein-like 1, Crebl1, Creb-related protein, CREB-RP, Cyclic AMP-dependent transcription factor ATF-6 alpha, cyclic AMP-dependent transcription factor ATF-6 beta, DKFZp686P2194, ESTM49, FLJ21663, G13, Processed cyclic AMP-dependent transcription factor ATF-6 alpha, Processed cyclic AMP-dependent transcription factor ATF-6 beta, Protein G13
Gene Symbols
ATF6, ATF6B
Isotype
IgG
Purification Method
Protein A
Gene
ATF6
Related Products
Description
- ATF6 is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes
- It binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3')
- Binding to ERSE requires binding of NF-Y to ERSE
- ATF6 could also be involved in activation of transcription by the serum response factor
- ATF6 exists as a homodimer and heterodimer with ATF6 beta
- The dimer interacts with the nuclear transcription factor Y (NF-Y) trimer through direct binding to NF-Y subunit C (NF-YC)
- It Interacts also with the transcription factors GTF2I, YY1 and SRF
- Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus
- The basic domain of ATF6 functions as a nuclear localization signal and the basic leucine-zipper domain is sufficient for association with the NF-Y trimer and binding to ERSE
- During the unfolded protein response an approximately 50 kDa fragment containing the cytoplasmic transcription factor domain is released by proteolysis
- The cleavage seems to be performed sequentially by site-1 and site-2 proteases
- ATF6 is N-glycosylated, phosphorylated in vitro by MAPK14/P38MAPK and belongs to the bZIP family.
Compare Similar Items
Show Difference
Antigen: ATF6
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: F6VAN0, O35451, P18850, Q99941
Gene ID (Entrez): 12915, 1388, 226641, 22926
Immunogen: Recombinant Human ATF6 protein, Ala423-Asn646 (Accession #P18850)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration: 0.5 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: 9130025P16Rik, 9630036G24, AA617266, AA789574, ACHM7, activating transcription factor 6, activating transcription factor 6 alpha, Activating transcription factor 6 beta, ATF 6, Atf6, ATF6 alpha, ATF6A, Atf6alpha, ATF6-alpha, Atf6b, ATF6beta, ATF6-beta, cAMP response element binding protein-related protein, cAMP response element-binding protein-related protein, cAMP responsive element binding protein-like 1, cAMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 beta, cAMP-responsive element-binding protein-like 1, Crebl1, Creb-related protein, CREB-RP, Cyclic AMP-dependent transcription factor ATF-6 alpha, cyclic AMP-dependent transcription factor ATF-6 beta, DKFZp686P2194, ESTM49, FLJ21663, G13, Processed cyclic AMP-dependent transcription factor ATF-6 alpha, Processed cyclic AMP-dependent transcription factor ATF-6 beta, Protein G13
Gene Symbols: ATF6, ATF6B
Isotype: IgG
Purification Method: Protein A
Gene: ATF6
Antigen:
ATF6
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
F6VAN0, O35451, P18850, Q99941
Gene ID (Entrez):
12915, 1388, 226641, 22926
Immunogen:
Recombinant Human ATF6 protein, Ala423-Asn646 (Accession #P18850)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration:
0.5 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
9130025P16Rik, 9630036G24, AA617266, AA789574, ACHM7, activating transcription factor 6, activating transcription factor 6 alpha, Activating transcription factor 6 beta, ATF 6, Atf6, ATF6 alpha, ATF6A, Atf6alpha, ATF6-alpha, Atf6b, ATF6beta, ATF6-beta, cAMP response element binding protein-related protein, cAMP response element-binding protein-related protein, cAMP responsive element binding protein-like 1, cAMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 beta, cAMP-responsive element-binding protein-like 1, Crebl1, Creb-related protein, CREB-RP, Cyclic AMP-dependent transcription factor ATF-6 alpha, cyclic AMP-dependent transcription factor ATF-6 beta, DKFZp686P2194, ESTM49, FLJ21663, G13, Processed cyclic AMP-dependent transcription factor ATF-6 alpha, Processed cyclic AMP-dependent transcription factor ATF-6 beta, Protein G13
Gene Symbols:
ATF6, ATF6B
Isotype:
IgG
Purification Method:
Protein A
Gene:
ATF6
Antigen: SERPINA10
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Porcine
Gene Accession No.: Q9UK55
Gene ID (Entrez): 51156
Immunogen: Recombinant Human SERPINA10 protein, Pro24-Leu444 (Accession #Q9UK55)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: plasma protein associated with liver regeneration, protein Z-dependent protease inhibitor, PZ-dependent protease inhibitor, PZI, Rasp1, RASP-1, Regeneration-associated serpin 1, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10, serpin A10, serpin family A member 10, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10, serpin peptidase inhibitor, clade A, member 10, Serpina10, UNQ707/PRO1358, Zpi
Gene Symbols: SERPINA10
Isotype: IgG2b κ
Purification Method: Protein A/G
Gene: SERPINA10
Antigen:
SERPINA10
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Porcine
Gene Accession No.:
Q9UK55
Gene ID (Entrez):
51156
Immunogen:
Recombinant Human SERPINA10 protein, Pro24-Leu444 (Accession #Q9UK55)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
plasma protein associated with liver regeneration, protein Z-dependent protease inhibitor, PZ-dependent protease inhibitor, PZI, Rasp1, RASP-1, Regeneration-associated serpin 1, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10, serpin A10, serpin family A member 10, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10, serpin peptidase inhibitor, clade A, member 10, Serpina10, UNQ707/PRO1358, Zpi
Gene Symbols:
SERPINA10
Isotype:
IgG2b κ
Purification Method:
Protein A/G
Gene:
SERPINA10
Antigen: SERPINA10
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Porcine, Rat
Gene Accession No.: Q62975, Q9UK55
Gene ID (Entrez): 171154, 51156
Immunogen: Recombinant Human SERPINA10 protein, Pro24-Leu444 (Accession #Q9UK55)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: plasma protein associated with liver regeneration, protein Z-dependent protease inhibitor, PZ-dependent protease inhibitor, PZI, Rasp1, RASP-1, Regeneration-associated serpin 1, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10, serpin A10, serpin family A member 10, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10, serpin peptidase inhibitor, clade A, member 10, Serpina10, UNQ707/PRO1358, Zpi
Gene Symbols: SERPINA10
Isotype: IgG2a κ
Purification Method: Protein A/G
Gene: SERPINA10
Antigen:
SERPINA10
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Porcine, Rat
Gene Accession No.:
Q62975, Q9UK55
Gene ID (Entrez):
171154, 51156
Immunogen:
Recombinant Human SERPINA10 protein, Pro24-Leu444 (Accession #Q9UK55)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
plasma protein associated with liver regeneration, protein Z-dependent protease inhibitor, PZ-dependent protease inhibitor, PZI, Rasp1, RASP-1, Regeneration-associated serpin 1, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10, serpin A10, serpin family A member 10, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10, serpin peptidase inhibitor, clade A, member 10, Serpina10, UNQ707/PRO1358, Zpi
Gene Symbols:
SERPINA10
Isotype:
IgG2a κ
Purification Method:
Protein A/G
Gene:
SERPINA10
Antigen: Hemoglobin
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Canine, Human
Gene Accession No.: P68871, P69905
Gene ID (Entrez): 3039, 3043
Immunogen: Native Dog HB protein (Accession #P60529;P60524)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration: 0.5 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: alpha one globin, alpha-1 globin, alpha-1-globin, alpha-2 globin chain, Alpha-globin, ALPHA-GLOBIN GENE, delta globin, Haemoglobin, Hb, HBA1, HbA1c, HBA2, HBA-T3, HBH, hemoglobin alpha 1 globin chain, Hemoglobin alpha chain, Hemoglobin subunit alpha, hemoglobin subunit alpha 1, hemoglobin, alpha 1
Gene Symbols: HBA1, HBB
Isotype: IgG
Purification Method: Protein A
Gene: HBB
Antigen:
Hemoglobin
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Canine, Human
Gene Accession No.:
P68871, P69905
Gene ID (Entrez):
3039, 3043
Immunogen:
Native Dog HB protein (Accession #P60529;P60524)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration:
0.5 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
alpha one globin, alpha-1 globin, alpha-1-globin, alpha-2 globin chain, Alpha-globin, ALPHA-GLOBIN GENE, delta globin, Haemoglobin, Hb, HBA1, HbA1c, HBA2, HBA-T3, HBH, hemoglobin alpha 1 globin chain, Hemoglobin alpha chain, Hemoglobin subunit alpha, hemoglobin subunit alpha 1, hemoglobin, alpha 1
Gene Symbols:
HBA1, HBB
Isotype:
IgG
Purification Method:
Protein A
Gene:
HBB