200020087
Laminin gamma-2 Monoclonal Antibody (D1), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Laminin gamma-2
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
AA589349, alternatively spliced laminin gamma2 chain, B2T, BM600, BM600-100kDa, cell-scattering factor 140 kDa subunit, CSF, CSF 140 kDa subunit, EBR2, EBR2A, Epiligrin subunit gamma, kalinin subunit gamma, Kalinin/nicein/epiligrin 100 kDa subunit, ladsin 140 kDa subunit, LAM LAMNB2, LAMB2T, LAMC2, lamimin, gamma 2, laminin B2t chain, laminin gamma2 chain, laminin subunit gamma 2, laminin subunit gamma-2, laminin, gamma 2, laminin-5 subunit gamma, LAMNB2, Large adhesive scatter factor 140 kDa subunit, nicein subunit gamma, nicein, 100kD, nicein, 100kDa
Gene Symbols
Lamc2
Isotype
IgG1 κ
Purification Method
Protein A/G
Gene
Lamc2
Clone
D1
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
Q13753
Gene ID (Entrez)
3918
Immunogen
Recombinant Human LAMC2 protein, Cys28-Cys196 (Accession #Q13753)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Related Products
Description
- Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes
- They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis
- Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains
- Each laminin chain is a multidomain protein encoded by a distinct gene
- Several isoforms of each chain have been described
- Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e
- alpha1beta1gamma1 heterotrimer is laminin 1
- The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo
- This gene encodes the gamma chain isoform laminin, gamma 2
- The gamma 2 chain, formerly thought to be a truncated version of beta chain (B2t), is highly homologous to the gamma 1 chain; however, it lacks domain VI, and domains V, IV and III are shorter
- It is expressed in several fetal tissues but differently from gamma 1, and is specifically localized to epithelial cells in skin, lung and kidney
- The gamma 2 chain together with alpha 3 and beta 3 chains constitute laminin 5 (earlier known as kalinin), which is an integral part of the anchoring filaments that connect epithelial cells to the underlying basement membrane
- The epithelium-specific expression of the gamma 2 chain implied its role as an epithelium attachment molecule, and mutations in this gene have been associated with junctional epidermolysis bullosa, a skin disease characterized by blisters due to disruption of the epidermal-dermal junction
- Two transcript variants resulting from alternative splicing of the 3' terminal exon, and encoding different isoforms of gamma 2 chain, have been described
- The two variants are differentially expressed in embryonic tissues, however, the biological significance of the two forms is not known
- Transcript variants utilizing alternative polyA_signal have also been noted in literature.
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Antigen: Laminin gamma-2
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: AA589349, alternatively spliced laminin gamma2 chain, B2T, BM600, BM600-100kDa, cell-scattering factor 140 kDa subunit, CSF, CSF 140 kDa subunit, EBR2, EBR2A, Epiligrin subunit gamma, kalinin subunit gamma, Kalinin/nicein/epiligrin 100 kDa subunit, ladsin 140 kDa subunit, LAM LAMNB2, LAMB2T, LAMC2, lamimin, gamma 2, laminin B2t chain, laminin gamma2 chain, laminin subunit gamma 2, laminin subunit gamma-2, laminin, gamma 2, laminin-5 subunit gamma, LAMNB2, Large adhesive scatter factor 140 kDa subunit, nicein subunit gamma, nicein, 100kD, nicein, 100kDa
Gene Symbols: Lamc2
Isotype: IgG1 κ
Purification Method: Protein A/G
Gene: Lamc2
Clone: D1
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q13753
Gene ID (Entrez): 3918
Immunogen: Recombinant Human LAMC2 protein, Cys28-Cys196 (Accession #Q13753)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen:
Laminin gamma-2
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
AA589349, alternatively spliced laminin gamma2 chain, B2T, BM600, BM600-100kDa, cell-scattering factor 140 kDa subunit, CSF, CSF 140 kDa subunit, EBR2, EBR2A, Epiligrin subunit gamma, kalinin subunit gamma, Kalinin/nicein/epiligrin 100 kDa subunit, ladsin 140 kDa subunit, LAM LAMNB2, LAMB2T, LAMC2, lamimin, gamma 2, laminin B2t chain, laminin gamma2 chain, laminin subunit gamma 2, laminin subunit gamma-2, laminin, gamma 2, laminin-5 subunit gamma, LAMNB2, Large adhesive scatter factor 140 kDa subunit, nicein subunit gamma, nicein, 100kD, nicein, 100kDa
Gene Symbols:
Lamc2
Isotype:
IgG1 κ
Purification Method:
Protein A/G
Gene:
Lamc2
Clone:
D1
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q13753
Gene ID (Entrez):
3918
Immunogen:
Recombinant Human LAMC2 protein, Cys28-Cys196 (Accession #Q13753)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen: Hemoglobin
Concentration: 0.5 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: alpha one globin, alpha-1 globin, alpha-1-globin, alpha-2 globin chain, Alpha-globin, ALPHA-GLOBIN GENE, delta globin, Haemoglobin, Hb, HBA1, HbA1c, HBA2, HBA-T3, HBH, hemoglobin alpha 1 globin chain, Hemoglobin alpha chain, Hemoglobin subunit alpha, hemoglobin subunit alpha 1, hemoglobin, alpha 1
Gene Symbols: HBA1, HBB
Isotype: IgG
Purification Method: Protein A
Gene: HBB
Clone: __
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Canine, Human, Non-human Primate, Porcine
Gene Accession No.: P02067, P68871, P69905
Gene ID (Entrez): 3039, 3043, 407066
Immunogen: Native Simian HB protein (Accession #P63108;P68223)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen:
Hemoglobin
Concentration:
0.5 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
alpha one globin, alpha-1 globin, alpha-1-globin, alpha-2 globin chain, Alpha-globin, ALPHA-GLOBIN GENE, delta globin, Haemoglobin, Hb, HBA1, HbA1c, HBA2, HBA-T3, HBH, hemoglobin alpha 1 globin chain, Hemoglobin alpha chain, Hemoglobin subunit alpha, hemoglobin subunit alpha 1, hemoglobin, alpha 1
Gene Symbols:
HBA1, HBB
Isotype:
IgG
Purification Method:
Protein A
Gene:
HBB
Clone:
__
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Canine, Human, Non-human Primate, Porcine
Gene Accession No.:
P02067, P68871, P69905
Gene ID (Entrez):
3039, 3043, 407066
Immunogen:
Native Simian HB protein (Accession #P63108;P68223)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen: HLA-B
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: A29 protein, antigen presenting molecule, AS, Aw-33, Aw-74, B-4901, B-5001, Bw-47, Bw-50, class I MHC, HLA-B antigen, DAQB-90C11.16, epididymis secretory protein Li 83, FLJ26655, HEL-S-83, histocompatibility antigen, HLA A, HLA -B, HLA B-40011, HLA B44, HLA class I antigen, HLA class I antigen HLA-B, HLA class I histocompatibility antigen, A alpha chain, HLA class I histocompatibility antigen, A-1 alpha chain, HLA class I histocompatibility antigen, A-30 alpha chain, HLA class I histocompatibility antigen, A-33 alpha chain, HLA class I histocompatibility antigen, A-74 alpha chain, HLA class I histocompatibility antigen, B alpha chain, HLA class I histocompatibility antigen, B-47 alpha chain, HLA class I histocompatibility antigen, B-50 alpha chain, HLA class I histocompatibility antigen, B-82 alpha chain, HLA locus, HLA molecule, HLAA, HLA-A, HLA-A locus alpha 2 domain, HLA-A null, HLA-A11, HLA-A33, HLA-Aw33.1, HLAB, HLA-B, HLA-B 1502, HLA-B alpha chain, HLA-B alpha chain (B*2706), HLA-B alpha chain (B*5002), HLA-B alpha-chain, HLA-B*45ZJ, HLA-B15, HLA-B35, HLA-B35 antigen, HLA-B-3506, HLA-B39, HLA-B-3905, HLA-B49, HLA-B50, HLA-B55, HLA-B-5502, HLA-B-5602, HLA-B59, HLA-B61, HLA-Bw50 antigen, HLA-Cw, HLA-DQB1, HLA-DRB1, Human leukocyte antigen A, hypothetical protein, lecocyte antigen B, leukocyt, Leukocyte Antigen, leukocyte antigen class I-A, leukocyte antigen class I-B, Leukoocyte Antigen, lymphocyte antigen, major histocompatability complex B antigen, major histocompatibility complex, class I, A, major histocompatibility complex, class I, B, MCH class I antigen, MHC 1, MHC antigen, MHC class 1 antigen, MHC class I alpha chain, MHC class I anitgen, MHC class I anti, MHC Class I antigen, MHC class I antigen A*30, MHC class I antigen A*33, MHC class I antigen A*74, MHC class I antigen B*47, MHC class I antigen B*50, MHC class I antigen B*82, MHC class I antigen GN00104, MHC class I antigen heavy chain, MHC class I antigen HLA-A heavy chain, MHC class I antigen HLA-A33, MHC class I antigen HLA-B alpha chain, MHC class I antigen HLA-B heavy chain, MHC class I antigen null protein, MHC class I antigen SHCHA, MHC class I antigene, MHC class I human leukocyte antigen, MHC class I molecule, MHC class I protein, MHC class II antigen, MHC class l antigen, MHC classI antigen, MHC HLA-B cell surface glycoprotein, MHC HLA-B transmembrane glycoprotein, MHC HLA-B27d, MHC HLA-B27-HS, MHC HLA-B39N, MHC1, SPDA1, truncated class I antigen, truncated MHC class I antigen
Gene Symbols: HLA-B
Isotype: IgG2b κ
Purification Method: Protein A/G
Gene: HLA-B
Clone: C1
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P01889
Gene ID (Entrez): 3106
Immunogen: Recombinant Human MHCB protein, Ser26-Val309 (Accession #P01889)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen:
HLA-B
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
A29 protein, antigen presenting molecule, AS, Aw-33, Aw-74, B-4901, B-5001, Bw-47, Bw-50, class I MHC, HLA-B antigen, DAQB-90C11.16, epididymis secretory protein Li 83, FLJ26655, HEL-S-83, histocompatibility antigen, HLA A, HLA -B, HLA B-40011, HLA B44, HLA class I antigen, HLA class I antigen HLA-B, HLA class I histocompatibility antigen, A alpha chain, HLA class I histocompatibility antigen, A-1 alpha chain, HLA class I histocompatibility antigen, A-30 alpha chain, HLA class I histocompatibility antigen, A-33 alpha chain, HLA class I histocompatibility antigen, A-74 alpha chain, HLA class I histocompatibility antigen, B alpha chain, HLA class I histocompatibility antigen, B-47 alpha chain, HLA class I histocompatibility antigen, B-50 alpha chain, HLA class I histocompatibility antigen, B-82 alpha chain, HLA locus, HLA molecule, HLAA, HLA-A, HLA-A locus alpha 2 domain, HLA-A null, HLA-A11, HLA-A33, HLA-Aw33.1, HLAB, HLA-B, HLA-B 1502, HLA-B alpha chain, HLA-B alpha chain (B*2706), HLA-B alpha chain (B*5002), HLA-B alpha-chain, HLA-B*45ZJ, HLA-B15, HLA-B35, HLA-B35 antigen, HLA-B-3506, HLA-B39, HLA-B-3905, HLA-B49, HLA-B50, HLA-B55, HLA-B-5502, HLA-B-5602, HLA-B59, HLA-B61, HLA-Bw50 antigen, HLA-Cw, HLA-DQB1, HLA-DRB1, Human leukocyte antigen A, hypothetical protein, lecocyte antigen B, leukocyt, Leukocyte Antigen, leukocyte antigen class I-A, leukocyte antigen class I-B, Leukoocyte Antigen, lymphocyte antigen, major histocompatability complex B antigen, major histocompatibility complex, class I, A, major histocompatibility complex, class I, B, MCH class I antigen, MHC 1, MHC antigen, MHC class 1 antigen, MHC class I alpha chain, MHC class I anitgen, MHC class I anti, MHC Class I antigen, MHC class I antigen A*30, MHC class I antigen A*33, MHC class I antigen A*74, MHC class I antigen B*47, MHC class I antigen B*50, MHC class I antigen B*82, MHC class I antigen GN00104, MHC class I antigen heavy chain, MHC class I antigen HLA-A heavy chain, MHC class I antigen HLA-A33, MHC class I antigen HLA-B alpha chain, MHC class I antigen HLA-B heavy chain, MHC class I antigen null protein, MHC class I antigen SHCHA, MHC class I antigene, MHC class I human leukocyte antigen, MHC class I molecule, MHC class I protein, MHC class II antigen, MHC class l antigen, MHC classI antigen, MHC HLA-B cell surface glycoprotein, MHC HLA-B transmembrane glycoprotein, MHC HLA-B27d, MHC HLA-B27-HS, MHC HLA-B39N, MHC1, SPDA1, truncated class I antigen, truncated MHC class I antigen
Gene Symbols:
HLA-B
Isotype:
IgG2b κ
Purification Method:
Protein A/G
Gene:
HLA-B
Clone:
C1
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P01889
Gene ID (Entrez):
3106
Immunogen:
Recombinant Human MHCB protein, Ser26-Val309 (Accession #P01889)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen: ACVR2A
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: activin A receptor type 2A, activin A receptor type IIA, activin A receptor, type IIA, activin receptor IIA, activin receptor type IIA, Activin receptor type-2A, Actrii, ActrIIa, ACTR-IIA, ACVR2, Acvr2a, rActR-II, TactrII, type II activin receptor
Gene Symbols: ACVR2A
Isotype: IgG2b κ
Purification Method: Protein A/G
Gene: ACVR2A
Clone: C1
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Porcine
Gene Accession No.: P27037
Gene ID (Entrez): 397282, 92
Immunogen: Recombinant Human ACVR2A protein, Ala20-Pro135 (Accession #P27037)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen:
ACVR2A
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
activin A receptor type 2A, activin A receptor type IIA, activin A receptor, type IIA, activin receptor IIA, activin receptor type IIA, Activin receptor type-2A, Actrii, ActrIIa, ACTR-IIA, ACVR2, Acvr2a, rActR-II, TactrII, type II activin receptor
Gene Symbols:
ACVR2A
Isotype:
IgG2b κ
Purification Method:
Protein A/G
Gene:
ACVR2A
Clone:
C1
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Porcine
Gene Accession No.:
P27037
Gene ID (Entrez):
397282, 92
Immunogen:
Recombinant Human ACVR2A protein, Ala20-Pro135 (Accession #P27037)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.