200020089

HLA-B Monoclonal Antibody (C1), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

HLA-B

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

A29 protein, antigen presenting molecule, AS, Aw-33, Aw-74, B-4901, B-5001, Bw-47, Bw-50, class I MHC, HLA-B antigen, DAQB-90C11.16, epididymis secretory protein Li 83, FLJ26655, HEL-S-83, histocompatibility antigen, HLA A, HLA -B, HLA B-40011, HLA B44, HLA class I antigen, HLA class I antigen HLA-B, HLA class I histocompatibility antigen, A alpha chain, HLA class I histocompatibility antigen, A-1 alpha chain, HLA class I histocompatibility antigen, A-30 alpha chain, HLA class I histocompatibility antigen, A-33 alpha chain, HLA class I histocompatibility antigen, A-74 alpha chain, HLA class I histocompatibility antigen, B alpha chain, HLA class I histocompatibility antigen, B-47 alpha chain, HLA class I histocompatibility antigen, B-50 alpha chain, HLA class I histocompatibility antigen, B-82 alpha chain, HLA locus, HLA molecule, HLAA, HLA-A, HLA-A locus alpha 2 domain, HLA-A null, HLA-A11, HLA-A33, HLA-Aw33.1, HLAB, HLA-B, HLA-B 1502, HLA-B alpha chain, HLA-B alpha chain (B*2706), HLA-B alpha chain (B*5002), HLA-B alpha-chain, HLA-B*45ZJ, HLA-B15, HLA-B35, HLA-B35 antigen, HLA-B-3506, HLA-B39, HLA-B-3905, HLA-B49, HLA-B50, HLA-B55, HLA-B-5502, HLA-B-5602, HLA-B59, HLA-B61, HLA-Bw50 antigen, HLA-Cw, HLA-DQB1, HLA-DRB1, Human leukocyte antigen A, hypothetical protein, lecocyte antigen B, leukocyt, Leukocyte Antigen, leukocyte antigen class I-A, leukocyte antigen class I-B, Leukoocyte Antigen, lymphocyte antigen, major histocompatability complex B antigen, major histocompatibility complex, class I, A, major histocompatibility complex, class I, B, MCH class I antigen, MHC 1, MHC antigen, MHC class 1 antigen, MHC class I alpha chain, MHC class I anitgen, MHC class I anti, MHC Class I antigen, MHC class I antigen A*30, MHC class I antigen A*33, MHC class I antigen A*74, MHC class I antigen B*47, MHC class I antigen B*50, MHC class I antigen B*82, MHC class I antigen GN00104, MHC class I antigen heavy chain, MHC class I antigen HLA-A heavy chain, MHC class I antigen HLA-A33, MHC class I antigen HLA-B alpha chain, MHC class I antigen HLA-B heavy chain, MHC class I antigen null protein, MHC class I antigen SHCHA, MHC class I antigene, MHC class I human leukocyte antigen, MHC class I molecule, MHC class I protein, MHC class II antigen, MHC class l antigen, MHC classI antigen, MHC HLA-B cell surface glycoprotein, MHC HLA-B transmembrane glycoprotein, MHC HLA-B27d, MHC HLA-B27-HS, MHC HLA-B39N, MHC1, SPDA1, truncated class I antigen, truncated MHC class I antigen

Gene Symbols

HLA-B

Isotype

IgG2b κ

Purification Method

Protein A/G

Gene

HLA-B

Clone

C1

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P01889

Gene ID (Entrez)

3106

Immunogen

Recombinant Human MHCB protein, Ser26-Val309 (Accession #P01889)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Related Products

Img

Fischer Scientific

200020334

Rat Monoclonal Antibody...

Img

Fischer Scientific

200020093

Mouse Monoclonal Antibody...

Img

Fischer Scientific

200020093

Mouse Monoclonal Antibody...

Img

Fischer Scientific

200020078

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

200020409

Mouse Monoclonal Antibody...

Img

Fischer Scientific

200020410

Mouse Monoclonal Antibody...

Img

Fischer Scientific

200020202

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

200020441

Mouse Monoclonal Antibody...

Description

  • HLA-B belongs to the HLA class I heavy chain paralogues
  • This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin)
  • The heavy chain is anchored in the membrane
  • Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen
  • They are expressed in nearly all cells
  • The heavy chain is approximately 45 kDa and its gene contains 8 exons
  • Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail
  • Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule
  • Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
  • Hundreds of HLA-B alleles have been described
  • HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Compare Similar Items

Show Difference

Img

Fischer Scientific

200020089

Mouse Monoclonal Antibody...


Antigen:
HLA-B

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
A29 protein, antigen presenting molecule, AS, Aw-33, Aw-74, B-4901, B-5001, Bw-47, Bw-50, class I MHC, HLA-B antigen, DAQB-90C11.16, epididymis secretory protein Li 83, FLJ26655, HEL-S-83, histocompatibility antigen, HLA A, HLA -B, HLA B-40011, HLA B44, HLA class I antigen, HLA class I antigen HLA-B, HLA class I histocompatibility antigen, A alpha chain, HLA class I histocompatibility antigen, A-1 alpha chain, HLA class I histocompatibility antigen, A-30 alpha chain, HLA class I histocompatibility antigen, A-33 alpha chain, HLA class I histocompatibility antigen, A-74 alpha chain, HLA class I histocompatibility antigen, B alpha chain, HLA class I histocompatibility antigen, B-47 alpha chain, HLA class I histocompatibility antigen, B-50 alpha chain, HLA class I histocompatibility antigen, B-82 alpha chain, HLA locus, HLA molecule, HLAA, HLA-A, HLA-A locus alpha 2 domain, HLA-A null, HLA-A11, HLA-A33, HLA-Aw33.1, HLAB, HLA-B, HLA-B 1502, HLA-B alpha chain, HLA-B alpha chain (B*2706), HLA-B alpha chain (B*5002), HLA-B alpha-chain, HLA-B*45ZJ, HLA-B15, HLA-B35, HLA-B35 antigen, HLA-B-3506, HLA-B39, HLA-B-3905, HLA-B49, HLA-B50, HLA-B55, HLA-B-5502, HLA-B-5602, HLA-B59, HLA-B61, HLA-Bw50 antigen, HLA-Cw, HLA-DQB1, HLA-DRB1, Human leukocyte antigen A, hypothetical protein, lecocyte antigen B, leukocyt, Leukocyte Antigen, leukocyte antigen class I-A, leukocyte antigen class I-B, Leukoocyte Antigen, lymphocyte antigen, major histocompatability complex B antigen, major histocompatibility complex, class I, A, major histocompatibility complex, class I, B, MCH class I antigen, MHC 1, MHC antigen, MHC class 1 antigen, MHC class I alpha chain, MHC class I anitgen, MHC class I anti, MHC Class I antigen, MHC class I antigen A*30, MHC class I antigen A*33, MHC class I antigen A*74, MHC class I antigen B*47, MHC class I antigen B*50, MHC class I antigen B*82, MHC class I antigen GN00104, MHC class I antigen heavy chain, MHC class I antigen HLA-A heavy chain, MHC class I antigen HLA-A33, MHC class I antigen HLA-B alpha chain, MHC class I antigen HLA-B heavy chain, MHC class I antigen null protein, MHC class I antigen SHCHA, MHC class I antigene, MHC class I human leukocyte antigen, MHC class I molecule, MHC class I protein, MHC class II antigen, MHC class l antigen, MHC classI antigen, MHC HLA-B cell surface glycoprotein, MHC HLA-B transmembrane glycoprotein, MHC HLA-B27d, MHC HLA-B27-HS, MHC HLA-B39N, MHC1, SPDA1, truncated class I antigen, truncated MHC class I antigen

Gene Symbols:
HLA-B

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
HLA-B

Clone:
C1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P01889

Gene ID (Entrez):
3106

Immunogen:
Recombinant Human MHCB protein, Ser26-Val309 (Accession #P01889)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020091

Mouse Monoclonal Antibody...


Antigen:
ACVR2A

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
activin A receptor type 2A, activin A receptor type IIA, activin A receptor, type IIA, activin receptor IIA, activin receptor type IIA, Activin receptor type-2A, Actrii, ActrIIa, ACTR-IIA, ACVR2, Acvr2a, rActR-II, TactrII, type II activin receptor

Gene Symbols:
ACVR2A

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
ACVR2A

Clone:
C1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine

Gene Accession No.:
P27037

Gene ID (Entrez):
397282, 92

Immunogen:
Recombinant Human ACVR2A protein, Ala20-Pro135 (Accession #P27037)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020092

Rabbit Polyclonal Antibody...


Antigen:
FABP1

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
14 kDa selenium-binding protein, FABP1, FABPL, Fabplg, fatty acid binding protein 1, fatty acid binding protein 1, liver, fatty acid binding protein liver, fatty acid-binding protein 1, Fatty acid-binding protein, liver, L-FABP, Liver-type fatty acid-binding protein, p14, SCP, SCP., Squalene- and sterol-carrier protein, Z-protein

Gene Symbols:
FABP1

Isotype:
IgG

Purification Method:
Protein A

Gene:
FABP1

Clone:
__

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse, Porcine, Rat

Gene Accession No.:
P02692, P07148, P12710, P49924

Gene ID (Entrez):
14080, 2168, 24360, 445535

Immunogen:
Recombinant Human FABP1 protein, Ser2-Ile127 (Accession #P07148)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020093

Mouse Monoclonal Antibody...


Antigen:
HLA-DRB1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
Clone P2-beta-3, DR-16, DRB1, DRw10, DW2.2/DR2.2, HLA class II histocompatibility antigen, DR-1 beta chain, HLA class II histocompatibility antigen, DRB1-15 beta chain, HLA class II histocompatibility antigen, DRB1-16 beta chain, HLA class II histocompatibility antigen, DRB1-3 chain, HLA-DR1B, HLA-DRB, HLA-DRB1, HLA-DRB2, human leucocyte antigen DRB1, lymphocyte antigen DRB1, major histocompatibility complex, class II, DR beta 1, MHC class II antigen, MHC class II antigen DRB1*15, MHC class II antigen DRB1*16, MHC class II antigen DRB1*3, MHC class II HLA-DR beta 1 chain, MHC class II HLA-DR-beta cell surface glycoprotein, MHC class II HLA-DRw10-beta, SS1

Gene Symbols:
HLA-DRB1

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
HLA-DRB1

Clone:
C3

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine, Rat

Gene Accession No.:
P01911

Gene ID (Entrez):
3123

Immunogen:
Recombinant Human HLA-DRB1 protein, Gly30-Ser266 (Accession #P01911)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.