200020409

alpha-1 Antitrypsin Monoclonal Antibody (H8), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

alpha-1 Antitrypsin

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

a-1 AT, A1A, a1-antitrypsin, A1AT, AAT, Aat2, Aat-2, alpha 1 antitrypsin, alpha-1 antitrypsin, alpha-1 protease inhibitor, Alpha-1 protease inhibitor 1, alpha-1-antiproteinase, Alpha-1-antitrypsin, alpha-1-antitrypsin (protease inhibitor), alpha-1-antitrypsin 1-1, alpha-1-antitrypsin 2, alpha-1-antitrypsin null, alpha1AT, alpha-1-protease inhibitor, alpha-1-proteinase inhibitor, Digestive Zymogen, Dom1, MGC23330, MGC9222, PI, PI1, PRO0684, PRO2209, PRO2275, protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin, protease inhibitor 1 (anti-elastase, antitrypsin, alpha-1), Protease Serine 1, serine (or cysteine) peptidase inhibitor, clade A, member 1A, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, serine (or cysteine) proteinase inhibitor, clade A (alpha-1antiproteinase, antitrypsin), member 1, serine (or cysteine) proteinase inhibitor, clade A, member 1, serine (or cysteine) proteinase inhibitor, clade A, member 1a, Serine Protease 1, serine protease inhibitor 1-1, Serine protease inhibitor A1a, serine protease inhibitor alpha 1, serine proteinase inhibitor, clade A, member 1, serpin A1, Serpin A1a, serpin family A member 1, serpin peptidase inhibitor clade A member 1, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, SERPINA1, Serpina1a, Short peptide from AAT, SPAAT, Spi1, Spi1-1, Spi1-3, TRP1, TRY1

Gene Symbols

SERPINA1, Serpina1a

Isotype

IgG1 κ

Purification Method

Protein A/G

Gene

SERPINA1

Clone

H8

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Mouse, Porcine, Rat

Gene Accession No.

P01009, P07758, P17475, P50447

Gene ID (Entrez)

20700, 24648, 397688, 5265

Immunogen

Recombinant Human a1AT protein, Glu25-Lys418 (Accession #P01009)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • Alpha-1-AT is synthesized in the liver and it acts as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung
  • In the absence of alpha-1-AT, these enzymes are not inhibited and they may digest pulmonary parenchyma
  • Alpha-1-AT deficiency is associated with chronic obstructive lung disease (emphysema) and less frequently with hepatic cirrhosis in infants and respiratory distress of the newborn
  • Increase in alpha-1-AT occurs as an acute phase response to tissue necrosis and inflammation
  • Serum level of alpha-1-AT is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis.

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Show Difference

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Fischer Scientific

200020409

Mouse Monoclonal Antibody...


Antigen:
alpha-1 Antitrypsin

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
a-1 AT, A1A, a1-antitrypsin, A1AT, AAT, Aat2, Aat-2, alpha 1 antitrypsin, alpha-1 antitrypsin, alpha-1 protease inhibitor, Alpha-1 protease inhibitor 1, alpha-1-antiproteinase, Alpha-1-antitrypsin, alpha-1-antitrypsin (protease inhibitor), alpha-1-antitrypsin 1-1, alpha-1-antitrypsin 2, alpha-1-antitrypsin null, alpha1AT, alpha-1-protease inhibitor, alpha-1-proteinase inhibitor, Digestive Zymogen, Dom1, MGC23330, MGC9222, PI, PI1, PRO0684, PRO2209, PRO2275, protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin, protease inhibitor 1 (anti-elastase, antitrypsin, alpha-1), Protease Serine 1, serine (or cysteine) peptidase inhibitor, clade A, member 1A, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, serine (or cysteine) proteinase inhibitor, clade A (alpha-1antiproteinase, antitrypsin), member 1, serine (or cysteine) proteinase inhibitor, clade A, member 1, serine (or cysteine) proteinase inhibitor, clade A, member 1a, Serine Protease 1, serine protease inhibitor 1-1, Serine protease inhibitor A1a, serine protease inhibitor alpha 1, serine proteinase inhibitor, clade A, member 1, serpin A1, Serpin A1a, serpin family A member 1, serpin peptidase inhibitor clade A member 1, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, SERPINA1, Serpina1a, Short peptide from AAT, SPAAT, Spi1, Spi1-1, Spi1-3, TRP1, TRY1

Gene Symbols:
SERPINA1, Serpina1a

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
SERPINA1

Clone:
H8

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse, Porcine, Rat

Gene Accession No.:
P01009, P07758, P17475, P50447

Gene ID (Entrez):
20700, 24648, 397688, 5265

Immunogen:
Recombinant Human a1AT protein, Glu25-Lys418 (Accession #P01009)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020410

Mouse Monoclonal Antibody...


Antigen:
alpha-1 Antitrypsin

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
a-1 AT, A1A, a1-antitrypsin, A1AT, AAT, Aat2, Aat-2, alpha 1 antitrypsin, alpha-1 antitrypsin, alpha-1 protease inhibitor, Alpha-1 protease inhibitor 1, alpha-1-antiproteinase, Alpha-1-antitrypsin, alpha-1-antitrypsin (protease inhibitor), alpha-1-antitrypsin 1-1, alpha-1-antitrypsin 2, alpha-1-antitrypsin null, alpha1AT, alpha-1-protease inhibitor, alpha-1-proteinase inhibitor, Digestive Zymogen, Dom1, MGC23330, MGC9222, PI, PI1, PRO0684, PRO2209, PRO2275, protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin, protease inhibitor 1 (anti-elastase, antitrypsin, alpha-1), Protease Serine 1, serine (or cysteine) peptidase inhibitor, clade A, member 1A, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, serine (or cysteine) proteinase inhibitor, clade A (alpha-1antiproteinase, antitrypsin), member 1, serine (or cysteine) proteinase inhibitor, clade A, member 1, serine (or cysteine) proteinase inhibitor, clade A, member 1a, Serine Protease 1, serine protease inhibitor 1-1, Serine protease inhibitor A1a, serine protease inhibitor alpha 1, serine proteinase inhibitor, clade A, member 1, serpin A1, Serpin A1a, serpin family A member 1, serpin peptidase inhibitor clade A member 1, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, SERPINA1, Serpina1a, Short peptide from AAT, SPAAT, Spi1, Spi1-1, Spi1-3, TRP1, TRY1

Gene Symbols:
SERPINA1

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
SERPINA1

Clone:
C5

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Rat

Gene Accession No.:
P17475

Gene ID (Entrez):
24648

Immunogen:
Recombinant Rat a1AT protein, Ala27-Lys181 (Accession #P17475)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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200020411

Mouse Monoclonal Antibody...


Antigen:
CD7

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
Cd7, CD7 antigen, CD7 antigen (p41), Cd7 molecule, GP40, LEU-9, p41 protein, T-cell antigen CD7, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp40, TP41

Gene Symbols:
CD7

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
CD7

Clone:
D5

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P09564

Gene ID (Entrez):
924

Immunogen:
Recombinant Eukaryotic Human CD7 protein, Ala26-Pro180 (Accession #P09564)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020413

Rat Monoclonal Antibody...


Antigen:
CD45

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
B220, cd45, CD45 antigen, CD45 antigen isoform 1 precursor, CD45 antigen isoform 2 precursor, CD45 antigen isoform 3 precursor, CD45 antigen isoform 4 precursor, CD45 antigen isoform 5 precursor, CD45 antigen isoform 6 precursor, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, leukocyte common antigen, CD45, loc, LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C, LY5, Ly-5, lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase lambda, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, protein tyrosine phosphatase, alternatively spliced, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen, T220 and B220

Gene Symbols:
PTPRC

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Gene:
PTPRC

Clone:
30-F11

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 661

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P06800

Gene ID (Entrez):
19264

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!