200020413

CD45 Monoclonal Antibody (30-F11), Brilliant Ultra Violet™ 661, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CD45

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias

B220, cd45, CD45 antigen, CD45 antigen isoform 1 precursor, CD45 antigen isoform 2 precursor, CD45 antigen isoform 3 precursor, CD45 antigen isoform 4 precursor, CD45 antigen isoform 5 precursor, CD45 antigen isoform 6 precursor, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, leukocyte common antigen, CD45, loc, LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C, LY5, Ly-5, lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase lambda, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, protein tyrosine phosphatase, alternatively spliced, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen, T220 and B220

Gene Symbols

PTPRC

Primary or Secondary

Primary

Content And Storage

4°, C, store in dark, DO NOT FREEZE!

Clone

30-F11

Applications

Flow Cytometry

Conjugate

Brilliant Ultraviolet 661

Host Species

Rat

Target Species

Mouse

Gene Accession No.

P06800

Gene ID (Entrez)

19264

Isotype

IgG2b κ

Purification Method

Affinity chromatography

Gene

PTPRC

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Description

  • CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes
  • CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues
  • CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
  • CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains
  • CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
  • CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
  • CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling
  • CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.

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Fischer Scientific

200020413

Rat Monoclonal Antibody...


Antigen:
CD45

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
B220, cd45, CD45 antigen, CD45 antigen isoform 1 precursor, CD45 antigen isoform 2 precursor, CD45 antigen isoform 3 precursor, CD45 antigen isoform 4 precursor, CD45 antigen isoform 5 precursor, CD45 antigen isoform 6 precursor, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, leukocyte common antigen, CD45, loc, LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C, LY5, Ly-5, lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase lambda, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, protein tyrosine phosphatase, alternatively spliced, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen, T220 and B220

Gene Symbols:
PTPRC

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Clone:
30-F11

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 661

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P06800

Gene ID (Entrez):
19264

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Gene:
PTPRC

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200020414

Syrian Hamster Monoclonal Antibody...


Antigen:
KLRG1

Concentration:
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Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
2F1, 2F1-Ag, CLEC15A, C-type lectin domain family 15 member A, C-type lectin domain family 15, member A, ITIM-containing receptor MAFA-L, killer cell lectin like receptor G1, killer cell lectin-like receptor subfamily G member 1, killer cell lectin-like receptor subfamily G, member 1, Klrg1, Mafa, MAFA-2F1, MAFAL, MAFA-L, MAFA-LIKE, MAFA-like receptor, Mast cell function-associated antigen, mast cell function-associated antigen (ITIM-containing), mast cell function-associated antigen 2F1, natural killer cell receptor

Gene Symbols:
Klrg1

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Clone:
2F1

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 421

Host Species:
Syrian Hamster

Target Species:
Mouse

Gene Accession No.:
O88713

Gene ID (Entrez):
50928

Isotype:
IgG

Purification Method:
Affinity chromatography

Gene:
Klrg1

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Antigen:
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Concentration:
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Classification:
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Form:
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Regulatory Status:
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Formulation:
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Gene Alias:
C87042, CANDF6, cytokine ML-1, IL17F, IL-17F, IL-24, ILN, Interleukin, interleukin 17F, Interleukin17F, interleukin-17F, interleukin-24, ML1, ML-1, mutant IL-17F

Gene Symbols:
IL17F

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Clone:
SHLR17

Applications:
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Conjugate:
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Target Species:
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Gene Accession No.:
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112744

Isotype:
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Purification Method:
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Gene:
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Concentration:
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Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
CD 14, CD14, CD14 antigen, CD14 molecule, cd14 monocyte, lipopolysaccharide receptor, lipoprotein receptor, LPSR antibody, monocyte differentiation antigen CD14, Monocyte differentiation antigen CD14, membrane-bound form, Monocyte differentiation antigen CD14, urinary form, monocyte differentiation antigen CD14, LOW QUALITY PROTEIN: monocyte differentiation antigen CD14, myeloid cell-specific leucine-rich glycoprotein, myeloid membrane glycoprotein precursor, sCD14, soluble CD14

Gene Symbols:
Cd14

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Clone:
61D3

Applications:
Flow Cytometry

Conjugate:
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Host Species:
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Target Species:
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Gene ID (Entrez):
929

Isotype:
IgG1 κ

Purification Method:
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Gene:
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