200020420
CD45R (B220) Monoclonal Antibody (RA3-6B2), Brilliant Violet™ 480, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
CD45R (B220)
Concentration
0.2 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias
B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen
Gene Symbols
PTPRC
Primary or Secondary
Primary
Content And Storage
4°, C, store in dark, DO NOT FREEZE!
Clone
RA3-6B2
Applications
Flow Cytometry
Conjugate
Brilliant Violet 480
Host Species
Rat
Target Species
Human, Mouse
Gene Accession No.
P06800, P08575
Gene ID (Entrez)
19264, 5788
Isotype
IgG2a κ
Purification Method
Affinity chromatography
Gene
PTPRC
Related Products
Description
- CD45R (PTPRC) is a member of the protein tyrosine phosphatase (PTP) family
- PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation
- CD45 contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains
- CD45 is specifically expressed in hematopoietic cells and has been shown to be an essential regulator of T- and B-cell antigen receptor signaling
- CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
- CD45 protein exists in multiple isoforms as a result of alternative splicing, and these isoforms differ in their extracellular domains, but share identical transmembrane and cytoplasmic domains
- Further, these CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
- In addition to its role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis
- CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
- Diseases associated with CD45 dysfunction include Severe Combined Immunodeficiency (T-cell negative, B-Cell Negative) and Hepatitis C.
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Antigen: CD45R (B220)
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias: B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen
Gene Symbols: PTPRC
Primary or Secondary: Primary
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Clone: RA3-6B2
Applications: Flow Cytometry
Conjugate: Brilliant Violet 480
Host Species: Rat
Target Species: Human, Mouse
Gene Accession No.: P06800, P08575
Gene ID (Entrez): 19264, 5788
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: PTPRC
Antigen:
CD45R (B220)
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen
Gene Symbols:
PTPRC
Primary or Secondary:
Primary
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Clone:
RA3-6B2
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 480
Host Species:
Rat
Target Species:
Human, Mouse
Gene Accession No.:
P06800, P08575
Gene ID (Entrez):
19264, 5788
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
PTPRC
Antigen: SIGLEC7
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: Adhesion inhibitory receptor molecule 1, adhesion inhibitory receptor molecule 1, siglec-7, AIRM1, AIRM-1, CD328, CDw328, D-siglec, p75, p75/ AIRM-1, p75/AIRM1, QA79, QA79 membrane protein, sialic acid binding Ig like lectin 7, sialic acid binding Ig-like lectin 7, sialic acid binding immunoglobulin-like lectin 7, sialic acid-binding Ig-like lectin 7, Siglec, SIGLEC19P, SIGLEC7, SIGLEC-7, SIGLECP2
Gene Symbols: SIGLEC7
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Clone: D5
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Rat
Gene Accession No.: Q9Y286
Gene ID (Entrez): 27036
Isotype: IgG1 κ
Purification Method: Protein A/G
Gene: SIGLEC7
Antigen:
SIGLEC7
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
Adhesion inhibitory receptor molecule 1, adhesion inhibitory receptor molecule 1, siglec-7, AIRM1, AIRM-1, CD328, CDw328, D-siglec, p75, p75/ AIRM-1, p75/AIRM1, QA79, QA79 membrane protein, sialic acid binding Ig like lectin 7, sialic acid binding Ig-like lectin 7, sialic acid binding immunoglobulin-like lectin 7, sialic acid-binding Ig-like lectin 7, Siglec, SIGLEC19P, SIGLEC7, SIGLEC-7, SIGLECP2
Gene Symbols:
SIGLEC7
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Clone:
D5
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Rat
Gene Accession No.:
Q9Y286
Gene ID (Entrez):
27036
Isotype:
IgG1 κ
Purification Method:
Protein A/G
Gene:
SIGLEC7
Antigen: SIGLEC7
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: Adhesion inhibitory receptor molecule 1, adhesion inhibitory receptor molecule 1, siglec-7, AIRM1, AIRM-1, CD328, CDw328, D-siglec, p75, p75/ AIRM-1, p75/AIRM1, QA79, QA79 membrane protein, sialic acid binding Ig like lectin 7, sialic acid binding Ig-like lectin 7, sialic acid binding immunoglobulin-like lectin 7, sialic acid-binding Ig-like lectin 7, Siglec, SIGLEC19P, SIGLEC7, SIGLEC-7, SIGLECP2
Gene Symbols: SIGLEC7
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Clone: D5
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Rat
Gene Accession No.: Q9Y286
Gene ID (Entrez): 27036
Isotype: IgG1 κ
Purification Method: Protein A/G
Gene: SIGLEC7
Antigen:
SIGLEC7
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
Adhesion inhibitory receptor molecule 1, adhesion inhibitory receptor molecule 1, siglec-7, AIRM1, AIRM-1, CD328, CDw328, D-siglec, p75, p75/ AIRM-1, p75/AIRM1, QA79, QA79 membrane protein, sialic acid binding Ig like lectin 7, sialic acid binding Ig-like lectin 7, sialic acid binding immunoglobulin-like lectin 7, sialic acid-binding Ig-like lectin 7, Siglec, SIGLEC19P, SIGLEC7, SIGLEC-7, SIGLECP2
Gene Symbols:
SIGLEC7
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Clone:
D5
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Rat
Gene Accession No.:
Q9Y286
Gene ID (Entrez):
27036
Isotype:
IgG1 κ
Purification Method:
Protein A/G
Gene:
SIGLEC7
Antigen: S100A8
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: 60B8AG, AI323541, B8Ag, CAGA, CAGB, calgranulin A, calgranulin B, calgranulin-A, Calgranulin-B, calprotectin L1H subunit, Calprotectin L1L subunit, CFAg, CGLA, CGLB, chemotactic cytokine CP-10, chemotactic S100 protein, CP-10, Cystic fibrosis antigen, L1Ag, leukocyte L1 complex heavy chain, Leukocyte L1 complex light chain, LIAG, MA387, MAC387, MIF, Migration inhibitory factor-related protein 14, migration inhibitory factor-related protein 8, MRP14, MRP-14, MRP8, MRP-8, NIF, P14, p8, Pro-inflammatory S100 cytokine, protein S100-A8, Protein S100-A9, S100 A8, S100 calcium binding protein A8, S100 calcium binding protein A8 (calgranulin A), S100 calcium binding protein A9, S100 calcium-binding protein A8, S100 calcium-binding protein A8 (calgranulin A), S100 calcium-binding protein A9, S100 calcium-binding protein A9 (calgranulin B), S100A8, S100A9, Urinary stone protein band A
Gene Symbols: S100A8
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Clone: C6
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Mouse
Gene Accession No.: P05109, P27005
Gene ID (Entrez): 20201, 6279
Isotype: IgG2b κ
Purification Method: Protein A/G
Gene: S100A8
Antigen:
S100A8
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
60B8AG, AI323541, B8Ag, CAGA, CAGB, calgranulin A, calgranulin B, calgranulin-A, Calgranulin-B, calprotectin L1H subunit, Calprotectin L1L subunit, CFAg, CGLA, CGLB, chemotactic cytokine CP-10, chemotactic S100 protein, CP-10, Cystic fibrosis antigen, L1Ag, leukocyte L1 complex heavy chain, Leukocyte L1 complex light chain, LIAG, MA387, MAC387, MIF, Migration inhibitory factor-related protein 14, migration inhibitory factor-related protein 8, MRP14, MRP-14, MRP8, MRP-8, NIF, P14, p8, Pro-inflammatory S100 cytokine, protein S100-A8, Protein S100-A9, S100 A8, S100 calcium binding protein A8, S100 calcium binding protein A8 (calgranulin A), S100 calcium binding protein A9, S100 calcium-binding protein A8, S100 calcium-binding protein A8 (calgranulin A), S100 calcium-binding protein A9, S100 calcium-binding protein A9 (calgranulin B), S100A8, S100A9, Urinary stone protein band A
Gene Symbols:
S100A8
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Clone:
C6
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Mouse
Gene Accession No.:
P05109, P27005
Gene ID (Entrez):
20201, 6279
Isotype:
IgG2b κ
Purification Method:
Protein A/G
Gene:
S100A8