200020018

CD45.1 Monoclonal Antibody (A20), Brilliant Violet™ 650, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CD45.1

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias

B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, Leukocyte common antigen, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, PTPRC, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen

Gene Symbols

Ptprc

Primary or Secondary

Primary

Gene

Ptprc

Clone

A20

Applications

Flow Cytometry

Conjugate

Brilliant Violet 650

Host Species

Mouse

Target Species

Mouse

Gene Accession No.

P06800

Gene ID (Entrez)

19264

Isotype

IgG2a κ

Purification Method

Affinity chromatography

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Description

  • CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes
  • CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
  • CD45 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains
  • These CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
  • Besides the role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis
  • CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells.

Compare Similar Items

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Img

Fischer Scientific

200020018

Mouse Monoclonal Antibody...


Antigen:
CD45.1

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, Leukocyte common antigen, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, PTPRC, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen

Gene Symbols:
Ptprc

Primary or Secondary:
Primary

Gene:
Ptprc

Clone:
A20

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 650

Host Species:
Mouse

Target Species:
Mouse

Gene Accession No.:
P06800

Gene ID (Entrez):
19264

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

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200020021

Mouse Monoclonal Antibody...


Antigen:
CD206 (MMR)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
__

Gene Alias:
AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4

Gene Symbols:
Mrc1

Primary or Secondary:
Primary

Gene:
Mrc1

Clone:
19.2

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 711

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P22897

Gene ID (Entrez):
4360

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

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Mouse Monoclonal Antibody...


Antigen:
CD279 (PD-1)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
__

Gene Alias:
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2

Gene Symbols:
Pdcd1

Primary or Secondary:
Primary

Gene:
Pdcd1

Clone:
eBioJ105 (J105)

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 737

Host Species:
Mouse

Target Species:
Human, Rhesus Monkey

Gene Accession No.:
Q15116

Gene ID (Entrez):
100135775, 5133

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

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200020025

Mouse Monoclonal Antibody...


Antigen:
CD279 (PD-1)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
__

Gene Alias:
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2

Gene Symbols:
Pdcd1

Primary or Secondary:
Primary

Gene:
Pdcd1

Clone:
eBioJ105 (J105)

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 737

Host Species:
Mouse

Target Species:
Human, Rhesus Monkey

Gene Accession No.:
Q15116

Gene ID (Entrez):
100135775, 5133

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography