200020396
CD45R (B220) Monoclonal Antibody (RA3-6B2), Brilliant Ultra Violet™ 563, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
CD45R (B220)
Concentration
0.2 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias
B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen
Gene Symbols
PTPRC
Primary or Secondary
Primary
Content And Storage
4°, C, store in dark, DO NOT FREEZE!
Clone
RA3-6B2
Applications
Flow Cytometry
Conjugate
Brilliant Ultraviolet 563
Host Species
Rat
Target Species
Human, Mouse
Gene Accession No.
P06800, P08575
Gene ID (Entrez)
19264, 5788
Isotype
IgG2a κ
Purification Method
Affinity chromatography
Gene
PTPRC
Related Products
Description
- CD45R (PTPRC) is a member of the protein tyrosine phosphatase (PTP) family
- PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation
- CD45 contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains
- CD45 is specifically expressed in hematopoietic cells and has been shown to be an essential regulator of T- and B-cell antigen receptor signaling
- CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
- CD45 protein exists in multiple isoforms as a result of alternative splicing, and these isoforms differ in their extracellular domains, but share identical transmembrane and cytoplasmic domains
- Further, these CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
- In addition to its role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis
- CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
- Diseases associated with CD45 dysfunction include Severe Combined Immunodeficiency (T-cell negative, B-Cell Negative) and Hepatitis C.
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Antigen: CD45R (B220)
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias: B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen
Gene Symbols: PTPRC
Primary or Secondary: Primary
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Clone: RA3-6B2
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 563
Host Species: Rat
Target Species: Human, Mouse
Gene Accession No.: P06800, P08575
Gene ID (Entrez): 19264, 5788
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: PTPRC
Antigen:
CD45R (B220)
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen
Gene Symbols:
PTPRC
Primary or Secondary:
Primary
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Clone:
RA3-6B2
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 563
Host Species:
Rat
Target Species:
Human, Mouse
Gene Accession No.:
P06800, P08575
Gene ID (Entrez):
19264, 5788
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
PTPRC
Antigen: CD197 (CCR7)
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias: BLR2, Bukitt's lymphoma receptor 2, CC chemokine receptor 7, C-C chemokine receptor type 7, C-C CKR-7, C-C motif chemokine receptor 7, CC-CKR-7, CCR7, CCR-7, CD197, CDw197, chemokine (C-C motif) receptor 7, chemokine (C-C) receptor 7, Cmkbr7, EBI1, Ebi1h, EBV-induced G protein-coupled receptor 1, EBV-induced G-protein coupled receptor 1, Epstein-Barr virus induced gene 1, Epstein-Barr virus-induced G-protein coupled receptor 1, EVI1, lymphocyte-specific G protein-coupled peptide receptor, MIP-3 beta receptor
Gene Symbols: Ccr7
Primary or Secondary: Primary
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Clone: 3D12
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 563
Host Species: Rat
Target Species: Human
Gene Accession No.: P32248
Gene ID (Entrez): 1236
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: Ccr7
Antigen:
CD197 (CCR7)
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
BLR2, Bukitt's lymphoma receptor 2, CC chemokine receptor 7, C-C chemokine receptor type 7, C-C CKR-7, C-C motif chemokine receptor 7, CC-CKR-7, CCR7, CCR-7, CD197, CDw197, chemokine (C-C motif) receptor 7, chemokine (C-C) receptor 7, Cmkbr7, EBI1, Ebi1h, EBV-induced G protein-coupled receptor 1, EBV-induced G-protein coupled receptor 1, Epstein-Barr virus induced gene 1, Epstein-Barr virus-induced G-protein coupled receptor 1, EVI1, lymphocyte-specific G protein-coupled peptide receptor, MIP-3 beta receptor
Gene Symbols:
Ccr7
Primary or Secondary:
Primary
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Clone:
3D12
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 563
Host Species:
Rat
Target Species:
Human
Gene Accession No.:
P32248
Gene ID (Entrez):
1236
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
Ccr7
Antigen: KLRG1
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias: 2F1, 2F1-Ag, CLEC15A, C-type lectin domain family 15 member A, C-type lectin domain family 15, member A, ITIM-containing receptor MAFA-L, killer cell lectin like receptor G1, killer cell lectin-like receptor subfamily G member 1, killer cell lectin-like receptor subfamily G, member 1, Klrg1, Mafa, MAFA-2F1, MAFAL, MAFA-L, MAFA-LIKE, MAFA-like receptor, Mast cell function-associated antigen, mast cell function-associated antigen (ITIM-containing), mast cell function-associated antigen 2F1, natural killer cell receptor
Gene Symbols: Klrg1
Primary or Secondary: Primary
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Clone: 2F1
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 563
Host Species: Syrian Hamster
Target Species: Mouse
Gene Accession No.: O88713
Gene ID (Entrez): 50928
Isotype: IgG
Purification Method: Affinity chromatography
Gene: Klrg1
Antigen:
KLRG1
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
2F1, 2F1-Ag, CLEC15A, C-type lectin domain family 15 member A, C-type lectin domain family 15, member A, ITIM-containing receptor MAFA-L, killer cell lectin like receptor G1, killer cell lectin-like receptor subfamily G member 1, killer cell lectin-like receptor subfamily G, member 1, Klrg1, Mafa, MAFA-2F1, MAFAL, MAFA-L, MAFA-LIKE, MAFA-like receptor, Mast cell function-associated antigen, mast cell function-associated antigen (ITIM-containing), mast cell function-associated antigen 2F1, natural killer cell receptor
Gene Symbols:
Klrg1
Primary or Secondary:
Primary
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Clone:
2F1
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 563
Host Species:
Syrian Hamster
Target Species:
Mouse
Gene Accession No.:
O88713
Gene ID (Entrez):
50928
Isotype:
IgG
Purification Method:
Affinity chromatography
Gene:
Klrg1
Antigen: IL-17A
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias: Ctla8, CTLA-8, cytokine, cytotoxic T-lymphocyte-associated antigen 8, cytotoxic T-lymphocyte-associated protein 8, il 17, Il17, IL-17, IL17A, IL-17a, ILN, Interleukin, interleukin 17, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17 precursor, interleukin 17A, interleukin-17, Interleukin17A, interleukin-17A, R-IL-17-A
Gene Symbols: IL17A
Primary or Secondary: Primary
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Clone: eBio64DEC17
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 563
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q16552
Gene ID (Entrez): 3605
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Gene: IL17A
Antigen:
IL-17A
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
Ctla8, CTLA-8, cytokine, cytotoxic T-lymphocyte-associated antigen 8, cytotoxic T-lymphocyte-associated protein 8, il 17, Il17, IL-17, IL17A, IL-17a, ILN, Interleukin, interleukin 17, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17 precursor, interleukin 17A, interleukin-17, Interleukin17A, interleukin-17A, R-IL-17-A
Gene Symbols:
IL17A
Primary or Secondary:
Primary
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Clone:
eBio64DEC17
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 563
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q16552
Gene ID (Entrez):
3605
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Gene:
IL17A