200020400

IL-17A Monoclonal Antibody (eBio64DEC17), Brilliant Ultra Violet™ 563, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

IL-17A

Concentration

5 μL/Test

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias

Ctla8, CTLA-8, cytokine, cytotoxic T-lymphocyte-associated antigen 8, cytotoxic T-lymphocyte-associated protein 8, il 17, Il17, IL-17, IL17A, IL-17a, ILN, Interleukin, interleukin 17, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17 precursor, interleukin 17A, interleukin-17, Interleukin17A, interleukin-17A, R-IL-17-A

Gene Symbols

IL17A

Primary or Secondary

Primary

Content And Storage

4°, C, store in dark, DO NOT FREEZE!

Clone

eBio64DEC17

Applications

Flow Cytometry

Conjugate

Brilliant Ultraviolet 563

Host Species

Mouse

Target Species

Human

Gene Accession No.

Q16552

Gene ID (Entrez)

3605

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Gene

IL17A

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Description

  • Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection
  • IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217)
  • High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts
  • In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to secrete IL-6, IL-8, G-CSF, and PGE2
  • In the presence of human IL-17A, fibroblasts can sustain the proliferation of CD34+ hematopoietic progenitors and induce maturation into neutrophils
  • Mouse, rat, and human IL-17A can induce IL-6 secretion in mouse stromal cells, indicating that all homologs can recognize the mouse receptor
  • IL-17A regulates the activities of NF-kappa B and mitogen-activated protein kinases, stimulates the expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), and enhances the production of nitric oxide (NO).

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Show Difference

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Fischer Scientific

200020400

Mouse Monoclonal Antibody...


Antigen:
IL-17A

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
Ctla8, CTLA-8, cytokine, cytotoxic T-lymphocyte-associated antigen 8, cytotoxic T-lymphocyte-associated protein 8, il 17, Il17, IL-17, IL17A, IL-17a, ILN, Interleukin, interleukin 17, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17 precursor, interleukin 17A, interleukin-17, Interleukin17A, interleukin-17A, R-IL-17-A

Gene Symbols:
IL17A

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Clone:
eBio64DEC17

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 563

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q16552

Gene ID (Entrez):
3605

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Gene:
IL17A

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200020401

Syrian Hamster Monoclonal Antibody...


Antigen:
KLRG1

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
2F1, 2F1-Ag, CLEC15A, C-type lectin domain family 15 member A, C-type lectin domain family 15, member A, ITIM-containing receptor MAFA-L, killer cell lectin like receptor G1, killer cell lectin-like receptor subfamily G member 1, killer cell lectin-like receptor subfamily G, member 1, Klrg1, Mafa, MAFA-2F1, MAFAL, MAFA-L, MAFA-LIKE, MAFA-like receptor, Mast cell function-associated antigen, mast cell function-associated antigen (ITIM-containing), mast cell function-associated antigen 2F1, natural killer cell receptor

Gene Symbols:
Klrg1

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Clone:
2F1

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 615

Host Species:
Syrian Hamster

Target Species:
Mouse

Gene Accession No.:
O88713

Gene ID (Entrez):
50928

Isotype:
IgG

Purification Method:
Affinity chromatography

Gene:
Klrg1

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200020402

Mouse Monoclonal Antibody...


Antigen:
Dystrophin

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
apodystrophin-3, apodystrophin-I, BMD, CMD3B, dmd, dmd.1, dmd.1.L, DNADMD1, Dp427, Dp71, Duchenne muscular dystrophy (DMD), DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, DXSmh7, DXSmh9, dys, Dystrophin, dystrophin Dp40, dystrophin Dp71 isoform, dystrophin Dp71a, dystrophin Dp71ab, dystrophin Dp71b, dystrophin, gene 1 L homeolog, dystrophin, muscular dystrophy, GS1-19O24.1, mdx, MRX85, Muscular dystrophy Duchenne and Becker types, OTTHUMP00000215592, pke, utrn, utrophin, XELAEV_18012903mg, X-linked muscular dystrophy

Gene Symbols:
DMD

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Clone:
C8

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine, Rat

Gene Accession No.:
P11530, P11532, Q5GN48

Gene ID (Entrez):
1756, 24907, 497636

Isotype:
IgG2a κ

Purification Method:
Protein A/G

Gene:
DMD

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200020403

Mouse Monoclonal Antibody...


Antigen:
IDO

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
EC 1.13.11.52, IDO, IDO1, IDO-1, INDO, indolamine 2,3 dioxygenase, indole 2,3-dioxygenase, indoleamine, indoleamine 2,3-dioxygenase 1, indoleamine 23-dioxygenase, Indoleamine-2, indoleamine-pyrrole 2,3 dioxygenase, indoleamine-pyrrole 2,3-dioxygenase

Gene Symbols:
Ido1

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Clone:
C14

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine

Gene Accession No.:
P14902

Gene ID (Entrez):
100519877, 3620

Isotype:
IgG2a κ

Purification Method:
Protein A/G

Gene:
Ido1