200020393

IL-17F Monoclonal Antibody (SHLR17), Brilliant Ultra Violet™ 395, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

IL-17F

Concentration

5 μL/Test

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias

C87042, CANDF6, cytokine ML-1, IL17F, IL-17F, IL-24, ILN, Interleukin, interleukin 17F, Interleukin17F, interleukin-17F, interleukin-24, ML1, ML-1, mutant IL-17F

Gene Symbols

IL17F

Primary or Secondary

Primary

Content And Storage

4°, C, store in dark, DO NOT FREEZE!

Clone

SHLR17

Applications

Flow Cytometry

Conjugate

Brilliant Ultraviolet 395

Host Species

Rat

Target Species

Human

Gene Accession No.

Q96PD4

Gene ID (Entrez)

112744

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Gene

IL17F

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Description

  • IL-17F (Interleukin 17F, CTLA-8)) is a cytokine belonging to the IL-17 family that is produced by inflammatory cells such as activated T cells, mast cells, and basophils
  • IL-17F is involved in allergic airway inflammation, and can induce several cytokines, chemokines, and adhesion molecules in bronchial epithelial cells, vein endothelial cells, fibroblasts, and eosinophils
  • IL-17F may be secreted as a homodimer, or a heterodimer with IL17A
  • It acts by binding to the type I receptor, IL-17R, aiding recruitment of monocytes and neutrophils at the site of inflammation by increasing chemokine production
  • IL-17F also stimulates induction of other pro-inflammatory cytokines TNF alpha, IL-1 beta, IL-6, and IL-8, and reports strongly suggest the involvement of IL-17 in several chronic inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis
  • TGF-beta (differentiation) and IL-23 (expansion) are required for induction and maintenance of Th17 (IL-17 producing) cells, which in turn induce the other pro-inflammatory cytokines
  • IL-17F is produced, and exists, as a homo-dimer, with homology to a herpes virus early protein, is one of the six members (IL-17A-F) of this cytokine family, and is well characterized and highly expressed by activated effector memory T cells
  • IL-17F has been found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1.

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200020393

Rat Monoclonal Antibody...


Antigen:
IL-17F

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
C87042, CANDF6, cytokine ML-1, IL17F, IL-17F, IL-24, ILN, Interleukin, interleukin 17F, Interleukin17F, interleukin-17F, interleukin-24, ML1, ML-1, mutant IL-17F

Gene Symbols:
IL17F

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Clone:
SHLR17

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 395

Host Species:
Rat

Target Species:
Human

Gene Accession No.:
Q96PD4

Gene ID (Entrez):
112744

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Gene:
IL17F

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Antigen:
IgM

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
AGM1, IGHM, immunoglobulin heavy constant mu, MU, VH

Gene Symbols:
IGHM

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Clone:
SA-DA4

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 395

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P01871

Gene ID (Entrez):
3507

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Gene:
IGHM

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Antigen:
KLRG1

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
2F1, 2F1-Ag, CLEC15A, C-type lectin domain family 15 member A, C-type lectin domain family 15, member A, ITIM-containing receptor MAFA-L, killer cell lectin like receptor G1, killer cell lectin-like receptor subfamily G member 1, killer cell lectin-like receptor subfamily G, member 1, Klrg1, Mafa, MAFA-2F1, MAFAL, MAFA-L, MAFA-LIKE, MAFA-like receptor, Mast cell function-associated antigen, mast cell function-associated antigen (ITIM-containing), mast cell function-associated antigen 2F1, natural killer cell receptor

Gene Symbols:
Klrg1

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Clone:
2F1

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 496

Host Species:
Syrian Hamster

Target Species:
Mouse

Gene Accession No.:
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Gene ID (Entrez):
50928

Isotype:
IgG

Purification Method:
Affinity chromatography

Gene:
Klrg1

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Antigen:
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Concentration:
0.2 mg/mL

Classification:
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Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen

Gene Symbols:
PTPRC

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Clone:
RA3-6B2

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 563

Host Species:
Rat

Target Species:
Human, Mouse

Gene Accession No.:
P06800, P08575

Gene ID (Entrez):
19264, 5788

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Gene:
PTPRC