200020403

IDO Monoclonal Antibody (C14), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

IDO

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

EC 1.13.11.52, IDO, IDO1, IDO-1, INDO, indolamine 2,3 dioxygenase, indole 2,3-dioxygenase, indoleamine, indoleamine 2,3-dioxygenase 1, indoleamine 23-dioxygenase, Indoleamine-2, indoleamine-pyrrole 2,3 dioxygenase, indoleamine-pyrrole 2,3-dioxygenase

Gene Symbols

Ido1

Isotype

IgG2a κ

Purification Method

Protein A/G

Gene

Ido1

Clone

C14

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Porcine

Gene Accession No.

P14902

Gene ID (Entrez)

100519877, 3620

Immunogen

Recombinant Human IDO protein, Ala2-Gly403 (Accession #P14902)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • IDO1 is an intracellular heme-containing enzyme that catalyzes the oxidative cleavage of the indole ring of several important regulatory molecules like tryptophan, serotonin, and melatonin
  • By doing this, IDO1 initiates the production of biologically active metabolites, commonly referred to as kynurenines
  • IDO1 is widely expressed in a variety of human tissues as well as in macrophages and dendritic cells (DCs)
  • In inflammation, interferons (IFNs) act on specific receptors to trigger IDO1 induction
  • The production of IFN-gamma and induction of IDO1 represent important antimicrobial mechanisms
  • Degradation and depletion of tryptophan by IDO1 inhibits the growth of viruses, bacteria and parasites
  • Furthermore, IDO1 plays a complex and crucial role in immunoregulation during infection, pregnancy, autoimmunity, transplantation, and neoplasia.

Compare Similar Items

Show Difference

Img

Fischer Scientific

200020403

Mouse Monoclonal Antibody...


Antigen:
IDO

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
EC 1.13.11.52, IDO, IDO1, IDO-1, INDO, indolamine 2,3 dioxygenase, indole 2,3-dioxygenase, indoleamine, indoleamine 2,3-dioxygenase 1, indoleamine 23-dioxygenase, Indoleamine-2, indoleamine-pyrrole 2,3 dioxygenase, indoleamine-pyrrole 2,3-dioxygenase

Gene Symbols:
Ido1

Isotype:
IgG2a κ

Purification Method:
Protein A/G

Gene:
Ido1

Clone:
C14

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine

Gene Accession No.:
P14902

Gene ID (Entrez):
100519877, 3620

Immunogen:
Recombinant Human IDO protein, Ala2-Gly403 (Accession #P14902)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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200020404

Mouse Monoclonal Antibody...


Antigen:
Cofilin

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
18 kDa phosphoprotein, AA959946, CFL, Cfl1, CFL-1, Cof, COF1, cofilin, cofilin 1, cofilin 1 (non-muscle), cofilin 1, non-muscle, cofilin, non-muscle isoform, Cofilin1, Cofilin-1, cofilin-1-like protein, epididymis secretory protein Li 15, HEL-S-15, n-cofilin, p18

Gene Symbols:
CFL1

Isotype:
IgG2a κ

Purification Method:
Protein A/G

Gene:
CFL1

Clone:
C12

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Bovine, Human, Porcine

Gene Accession No.:
P10668, P23528, Q5E9F7

Gene ID (Entrez):
1072, 445532, 534553

Immunogen:
Recombinant Human CFL1 protein, Ser3-Leu161 (Accession #P23528)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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200020405

Mouse Monoclonal Antibody...


Antigen:
KIR2DS4

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
CD158 antigen-like family member I, CD158I, killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4, killer cell immunoglobulin-like receptor 2DS4, killer cell immunoglobulin-like receptor two domains short cytoplasmic tail 1, killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4, killer Ig receptor, killer inhibitory receptor 4-1-2, killer-cell immunoglobulin-like receptor, KIR antigen 2DS4, KIR1D, KIR2DS1, KIR2DS4, KIR-2DS4, KIR412, KKA3, MHC class I NK cell receptor, natural killer cell inhibitory receptor, natural killer cell receptor, natural killer-associated transcript 8, NKAT8, NKAT-8, p50 killer cell activating receptor KAR-K1d, P58 natural killer cell receptor clones CL-39/CL-17, p58 NK receptor CL-39/CL-17

Gene Symbols:
KIR2DS4

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
KIR2DS4

Clone:
C15

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P43632

Gene ID (Entrez):
3809

Immunogen:
Recombinant Human KIR2DS4 protein, Gln22-Ser302 (Accession #P43632)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020405

Mouse Monoclonal Antibody...


Antigen:
KIR2DS4

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
CD158 antigen-like family member I, CD158I, killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4, killer cell immunoglobulin-like receptor 2DS4, killer cell immunoglobulin-like receptor two domains short cytoplasmic tail 1, killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4, killer Ig receptor, killer inhibitory receptor 4-1-2, killer-cell immunoglobulin-like receptor, KIR antigen 2DS4, KIR1D, KIR2DS1, KIR2DS4, KIR-2DS4, KIR412, KKA3, MHC class I NK cell receptor, natural killer cell inhibitory receptor, natural killer cell receptor, natural killer-associated transcript 8, NKAT8, NKAT-8, p50 killer cell activating receptor KAR-K1d, P58 natural killer cell receptor clones CL-39/CL-17, p58 NK receptor CL-39/CL-17

Gene Symbols:
KIR2DS4

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
KIR2DS4

Clone:
C15

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P43632

Gene ID (Entrez):
3809

Immunogen:
Recombinant Human KIR2DS4 protein, Gln22-Ser302 (Accession #P43632)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.