200020405

KIR2DS4 Monoclonal Antibody (C15), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

KIR2DS4

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

CD158 antigen-like family member I, CD158I, killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4, killer cell immunoglobulin-like receptor 2DS4, killer cell immunoglobulin-like receptor two domains short cytoplasmic tail 1, killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4, killer Ig receptor, killer inhibitory receptor 4-1-2, killer-cell immunoglobulin-like receptor, KIR antigen 2DS4, KIR1D, KIR2DS1, KIR2DS4, KIR-2DS4, KIR412, KKA3, MHC class I NK cell receptor, natural killer cell inhibitory receptor, natural killer cell receptor, natural killer-associated transcript 8, NKAT8, NKAT-8, p50 killer cell activating receptor KAR-K1d, P58 natural killer cell receptor clones CL-39/CL-17, p58 NK receptor CL-39/CL-17

Gene Symbols

KIR2DS4

Isotype

IgG2b κ

Purification Method

Protein A/G

Gene

KIR2DS4

Clone

C15

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P43632

Gene ID (Entrez)

3809

Immunogen

Recombinant Human KIR2DS4 protein, Gln22-Ser302 (Accession #P43632)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • Description Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells
  • The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC)
  • The gene content of the KIR gene cluster varies among haplotypes, although several &quoteframework&quote genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2)
  • The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain
  • KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals
  • The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.

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Fischer Scientific

200020405

Mouse Monoclonal Antibody...


Antigen:
KIR2DS4

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
CD158 antigen-like family member I, CD158I, killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4, killer cell immunoglobulin-like receptor 2DS4, killer cell immunoglobulin-like receptor two domains short cytoplasmic tail 1, killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4, killer Ig receptor, killer inhibitory receptor 4-1-2, killer-cell immunoglobulin-like receptor, KIR antigen 2DS4, KIR1D, KIR2DS1, KIR2DS4, KIR-2DS4, KIR412, KKA3, MHC class I NK cell receptor, natural killer cell inhibitory receptor, natural killer cell receptor, natural killer-associated transcript 8, NKAT8, NKAT-8, p50 killer cell activating receptor KAR-K1d, P58 natural killer cell receptor clones CL-39/CL-17, p58 NK receptor CL-39/CL-17

Gene Symbols:
KIR2DS4

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
KIR2DS4

Clone:
C15

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P43632

Gene ID (Entrez):
3809

Immunogen:
Recombinant Human KIR2DS4 protein, Gln22-Ser302 (Accession #P43632)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Antigen:
C1S

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
AA959438, AI255193, AI327365, basic proline-rich peptide IB-1, C1 esterase, C1s, C1s1, C1sa, complement C1s, complement C1s subcomponent, Complement C1s subcomponent heavy chain, Complement C1s subcomponent light chain, Complement C1s-A subcomponent, Complement C1s-A subcomponent heavy chain, Complement C1s-A subcomponent light chain, Complement component 1 subcomponent s, complement component 1 subcomponent s-A, complement component 1, s subcomponent, complement component 1, s subcomponent 1, complement component C1SA, r-gsp, serine protease

Gene Symbols:
C1S

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
C1S

Clone:
C2

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P09871

Gene ID (Entrez):
716

Immunogen:
Recombinant Human C1s protein, Ile438-Pro685 (Accession #P09871)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Mouse Monoclonal Antibody...


Antigen:
FABP4

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
3T3-L1 lipid-binding protein, 422/aP2, adipocyte fatty acid binding protein, Adipocyte lipid binding protein, adipocyte lipid-binding protein, adipocyte protein aP2, adipocyte-type fatty acid-binding protein, AFABP, A-FABP, ALBP, ALBP/Ap2, Ap2, epididymis secretory protein Li 104, FABP4, fatty acid binding protein 4, Fatty acid binding protein 4 adipocyte, fatty acid binding protein 4, adipocyte, fatty acid-binding protein 4, Fatty acid-binding protein, adipocyte, HEL S 104, HEL-S-104, Lbpl, myelin P2 protein homolog, P15, P2 adipocyte protein, Protein 422

Gene Symbols:
FABP4

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
FABP4

Clone:
C12

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine, Rat

Gene Accession No.:
O97788, P15090, P70623

Gene ID (Entrez):
2167, 399533, 79451

Immunogen:
Recombinant Human FABP4 protein, Cys2-Ala132 (Accession #P15090)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Antigen:
alpha-1 Antitrypsin

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
a-1 AT, A1A, a1-antitrypsin, A1AT, AAT, Aat2, Aat-2, alpha 1 antitrypsin, alpha-1 antitrypsin, alpha-1 protease inhibitor, Alpha-1 protease inhibitor 1, alpha-1-antiproteinase, Alpha-1-antitrypsin, alpha-1-antitrypsin (protease inhibitor), alpha-1-antitrypsin 1-1, alpha-1-antitrypsin 2, alpha-1-antitrypsin null, alpha1AT, alpha-1-protease inhibitor, alpha-1-proteinase inhibitor, Digestive Zymogen, Dom1, MGC23330, MGC9222, PI, PI1, PRO0684, PRO2209, PRO2275, protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin, protease inhibitor 1 (anti-elastase, antitrypsin, alpha-1), Protease Serine 1, serine (or cysteine) peptidase inhibitor, clade A, member 1A, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, serine (or cysteine) proteinase inhibitor, clade A (alpha-1antiproteinase, antitrypsin), member 1, serine (or cysteine) proteinase inhibitor, clade A, member 1, serine (or cysteine) proteinase inhibitor, clade A, member 1a, Serine Protease 1, serine protease inhibitor 1-1, Serine protease inhibitor A1a, serine protease inhibitor alpha 1, serine proteinase inhibitor, clade A, member 1, serpin A1, Serpin A1a, serpin family A member 1, serpin peptidase inhibitor clade A member 1, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, SERPINA1, Serpina1a, Short peptide from AAT, SPAAT, Spi1, Spi1-1, Spi1-3, TRP1, TRY1

Gene Symbols:
SERPINA1, Serpina1a

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
SERPINA1

Clone:
H8

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse, Porcine, Rat

Gene Accession No.:
P01009, P07758, P17475, P50447

Gene ID (Entrez):
20700, 24648, 397688, 5265

Immunogen:
Recombinant Human a1AT protein, Glu25-Lys418 (Accession #P01009)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.