200020103

CRHBP Monoclonal Antibody (D2), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CRHBP

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

corticotropin releasing factor binding protein, corticotropin releasing hormone binding protein, corticotropin releasing hormone-binding protein, corticotropin-releasing factor-binding protein, Corticotropin-releasing hormone-binding protein, CRF-binding protein, CRFBP, CRF-BP, Crhbp, CRH-BP

Gene Symbols

CRHBP

Isotype

IgG1 κ

Purification Method

Protein A/G

Gene

CRHBP

Clone

D2

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Rat

Gene Accession No.

P24388

Gene ID (Entrez)

29625

Immunogen

Recombinant Rat CRHBP protein, Tyr25-Leu322 (Accession #P24388)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • Response to stress in mammals requires an intact hypothalamic-pituitary-adrenal axis
  • The proximal part of the response is mediated by secretion of corticotropin-releasing hormone (CRH) by the paraventricular nucleus of the hypothalamus
  • CRH is a 41 amino acid peptide derived by enzymatic cleavage from a 191 amino acid preprohormone
  • CRH is produced not only in the hypothalamus but also in peripheral tissues, such as T lymphocytes; it is highly expressed in human placenta
  • Glucocorticoids stimulate placental CRH synthesis and secretion in primary cultures of human placenta
  • This stimulation is in contrast to the glucocorticoid suppression of CRH expression in hypothalamus
  • The gene which encodes CRH maps to human chromosome 8q13
  • Human plasma contains a CRH-binding protein, CRH-BP (also designated CRF-BP) which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy
  • The gene which encodes CRF-BP maps to human chromosome 5q11.2-q13.3.

Compare Similar Items

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Img

Fischer Scientific

200020103

Mouse Monoclonal Antibody...


Antigen:
CRHBP

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
corticotropin releasing factor binding protein, corticotropin releasing hormone binding protein, corticotropin releasing hormone-binding protein, corticotropin-releasing factor-binding protein, Corticotropin-releasing hormone-binding protein, CRF-binding protein, CRFBP, CRF-BP, Crhbp, CRH-BP

Gene Symbols:
CRHBP

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
CRHBP

Clone:
D2

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Rat

Gene Accession No.:
P24388

Gene ID (Entrez):
29625

Immunogen:
Recombinant Rat CRHBP protein, Tyr25-Leu322 (Accession #P24388)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Fischer Scientific

200020105

Mouse Monoclonal Antibody...


Antigen:
FAP

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
170 kDa melanoma membrane-bound gelatinase, Antiplasmin-cleaving enzyme FAP, soluble form, APCE, Dipeptidyl peptidase FAP, DPPIV, Fap, FAPA, FAPalpha, fibroblast activation protein, fibroblast activation protein alpha, fibroblast activation protein, alpha, gelatine degradation protease FAP, Integral membrane serine protease, post-proline cleaving enzyme, Prolyl endopeptidase FAP, seprase, Serine integral membrane protease, SIMP, Surface-expressed protease

Gene Symbols:
FAP

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
FAP

Clone:
D3

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine

Gene Accession No.:
Q12884

Gene ID (Entrez):
100736572, 2191

Immunogen:
Recombinant Human FAPa protein, Ile523-Asp760 (Accession #Q12884)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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200020106

Rabbit Polyclonal Antibody...


Antigen:
BACE2

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
1110059C24Rik, 56 kDa aspartic-like protease, AEPLC, AI850424, ALP56, ARP1, asp 1, ASP1, ASP21, Aspartic-like protease 56 kDa, Aspartyl protease 1, Bace2, BAE2, be, beta secretase 2, Beta-secretase 2, beta-site amyloid beta A4 precursor protein-cleaving enzyme 2, beta-site amyloid precursor protein cleaving enzyme 2, Beta-site APP cleaving enzyme 2, beta-site APP-cleaving enzyme 2, CDA13, CEAP1, Down region aspartic protease, Down syndrome region aspartic protease, DRAP, memapsin 1, memapsin-1, Membrane-associated aspartic protease 1, theta-secretase, transmembrane aspartic proteinase Asp1, UNQ418/PRO852

Gene Symbols:
BACE2

Isotype:
IgG

Purification Method:
Protein A

Gene:
BACE2

Clone:
__

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
Q6IE75, Q9JL18, Q9Y5Z0

Gene ID (Entrez):
25825, 288227, 56175

Immunogen:
Recombinant Rat BACE2 protein, Gly242-Val502 (Accession #Q6IE75)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020106

Rabbit Polyclonal Antibody...


Antigen:
BACE2

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
1110059C24Rik, 56 kDa aspartic-like protease, AEPLC, AI850424, ALP56, ARP1, asp 1, ASP1, ASP21, Aspartic-like protease 56 kDa, Aspartyl protease 1, Bace2, BAE2, be, beta secretase 2, Beta-secretase 2, beta-site amyloid beta A4 precursor protein-cleaving enzyme 2, beta-site amyloid precursor protein cleaving enzyme 2, Beta-site APP cleaving enzyme 2, beta-site APP-cleaving enzyme 2, CDA13, CEAP1, Down region aspartic protease, Down syndrome region aspartic protease, DRAP, memapsin 1, memapsin-1, Membrane-associated aspartic protease 1, theta-secretase, transmembrane aspartic proteinase Asp1, UNQ418/PRO852

Gene Symbols:
BACE2

Isotype:
IgG

Purification Method:
Protein A

Gene:
BACE2

Clone:
__

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
Q6IE75, Q9JL18, Q9Y5Z0

Gene ID (Entrez):
25825, 288227, 56175

Immunogen:
Recombinant Rat BACE2 protein, Gly242-Val502 (Accession #Q6IE75)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.