200020157

Calnexin Monoclonal Antibody (C2), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Calnexin

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

1110069N15Rik, AI988026, calmegin, calnexin, canx, canx-a, canx-b, clgn, clnx, cnx, D11Ertd153e, FLJ26570, hypothetical protein, IP90, Major histocompatibility complex class I antigen-binding protein p88, p88, P90, PP90, pp90 precursor

Gene Symbols

CANX

Isotype

IgG2b κ

Purification Method

Protein A/G

Gene

CANX

Clone

C2

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Bovine, Canine, Human, Porcine, Rat

Gene Accession No.

P24643, P27824, P35565

Gene ID (Entrez)

100519184, 29144, 403908, 407129, 821

Immunogen

Recombinant Human CNX protein, Thr239-Ala461 (Accession #P27824)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • Calnexin, also referred to as IP90, p88 and p90, is an approximately 90 kDa integral membrane protein of the endoplasmic reticulum (ER)
  • Many resident ER proteins act as molecular chaperones and participate in the proper folding of polypeptides and their assembly into multisubunit proteins
  • Studies indicate that calnexin associates with the major histocompatibility complex (MHC) class I heavy chains, partial complexes of the T cell receptor and B cell membrane immunoglobulin, but not with completed receptor complexes
  • It has been shown that calnexin is a chaperone that retains incompletely or improperly folded proteins in the ER
  • The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble ER resident proteins such as GRP78 and GRP94 and protein disulfide isomerase
  • Integral membrane ER resident proteins, like calnexin, often lack this KDEL sequence but contain positively charged cytosolic residues that ensure ER retention
  • Calnexin contains a large ER luminal domain (461 amino acids), a transmembrane segment (22 amino acids), and a cytoplasmic tail (89 amino acids).

Compare Similar Items

Show Difference

Img

Fischer Scientific

200020157

Mouse Monoclonal Antibody...


Antigen:
Calnexin

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
1110069N15Rik, AI988026, calmegin, calnexin, canx, canx-a, canx-b, clgn, clnx, cnx, D11Ertd153e, FLJ26570, hypothetical protein, IP90, Major histocompatibility complex class I antigen-binding protein p88, p88, P90, PP90, pp90 precursor

Gene Symbols:
CANX

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
CANX

Clone:
C2

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Bovine, Canine, Human, Porcine, Rat

Gene Accession No.:
P24643, P27824, P35565

Gene ID (Entrez):
100519184, 29144, 403908, 407129, 821

Immunogen:
Recombinant Human CNX protein, Thr239-Ala461 (Accession #P27824)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020158

Mouse Monoclonal Antibody...


Antigen:
CK1 delta

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
1200006A05Rik, AA409348, ASPS, casein kinase 1, casein kinase 1 delta, casein kinase 1, delta, casein kinase I isoform delta, CK1d, CK1delta, CKId, CKIdelta, CKI-delta, CSNK1D, D930010H05Rik, FASPS2, HCKID, HGNC:2452, Tau-protein kinase CSNK1D

Gene Symbols:
CSNK1D

Isotype:
IgG2a κ

Purification Method:
Protein A/G

Gene:
CSNK1D

Clone:
C3

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine, Rat

Gene Accession No.:
P48730, Q06486

Gene ID (Entrez):
100625051, 1453, 64462

Immunogen:
Recombinant Human CSNK1d protein, Met1-Lys409 (Accession #P48730)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Fischer Scientific

200020159

Rabbit Polyclonal Antibody...


Antigen:
GPX3

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
AA960521, EGPx, extracellular glutathione peroxidase, extracellular GPx, glutathione peroxidase 3, glutathione peroxidase 3 (plasma), GPx, Gpx3, GPx-3, Gpxp, GPx-P, GSHPx-3, GSHPx-P, plasma form, plasma glutathione peroxidase, plasma GPx

Gene Symbols:
Gpx3

Isotype:
IgG

Purification Method:
Protein A

Gene:
Gpx3

Clone:
__

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse, Rat

Gene Accession No.:
P23764, P46412

Gene ID (Entrez):
14778, 64317

Immunogen:
Recombinant Mouse GPX3 protein, Arg3-Tyr72 (Accession #P46412)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020159

Rabbit Polyclonal Antibody...


Antigen:
GPX3

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
AA960521, EGPx, extracellular glutathione peroxidase, extracellular GPx, glutathione peroxidase 3, glutathione peroxidase 3 (plasma), GPx, Gpx3, GPx-3, Gpxp, GPx-P, GSHPx-3, GSHPx-P, plasma form, plasma glutathione peroxidase, plasma GPx

Gene Symbols:
Gpx3

Isotype:
IgG

Purification Method:
Protein A

Gene:
Gpx3

Clone:
__

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse, Rat

Gene Accession No.:
P23764, P46412

Gene ID (Entrez):
14778, 64317

Immunogen:
Recombinant Mouse GPX3 protein, Arg3-Tyr72 (Accession #P46412)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.